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Page 1
Persistent activation of the Fyn/ERK kinase signaling axis mediates imatinib resistance in chronic myelogenous leukemia cells through upregulation of intracellular SPARC.
Fenouille N, Puissant A, Dufies M, Robert G, Jacquel A, Ohanna M, Deckert M, Pasquet JM, Mahon FX, Cassuto JP, Raynaud S, Tartare-Deckert S, Auberger P. Fenouille N, et al. Among authors: ohanna m. Cancer Res. 2010 Dec 1;70(23):9659-70. doi: 10.1158/0008-5472.CAN-10-2034. Epub 2010 Nov 23. Cancer Res. 2010. PMID: 21098700
Aurora B is regulated by the mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) signaling pathway and is a valuable potential target in melanoma cells.
Bonet C, Giuliano S, Ohanna M, Bille K, Allegra M, Lacour JP, Bahadoran P, Rocchi S, Ballotti R, Bertolotto C. Bonet C, et al. Among authors: ohanna m. J Biol Chem. 2012 Aug 24;287(35):29887-98. doi: 10.1074/jbc.M112.371682. Epub 2012 Jul 5. J Biol Chem. 2012. PMID: 22767597 Free PMC article.
Tumour-derived SPARC drives vascular permeability and extravasation through endothelial VCAM1 signalling to promote metastasis.
Tichet M, Prod'Homme V, Fenouille N, Ambrosetti D, Mallavialle A, Cerezo M, Ohanna M, Audebert S, Rocchi S, Giacchero D, Boukari F, Allegra M, Chambard JC, Lacour JP, Michiels JF, Borg JP, Deckert M, Tartare-Deckert S. Tichet M, et al. Among authors: ohanna m. Nat Commun. 2015 Apr 30;6:6993. doi: 10.1038/ncomms7993. Nat Commun. 2015. PMID: 25925867 Free article.
Deciphering the Role of Oncogenic MITFE318K in Senescence Delay and Melanoma Progression.
Bonet C, Luciani F, Ottavi JF, Leclerc J, Jouenne FM, Boncompagni M, Bille K, Hofman V, Bossis G, Marco de Donatis G, Strub T, Cheli Y, Ohanna M, Luciano F, Marchetti S, Rocchi S, Birling MC, Avril MF, Poulalhon N, Luc T, Hofman P, Lacour JP, Davidson I, Bressac-de Paillerets B, Ballotti R, Marine JC, Bertolotto C. Bonet C, et al. Among authors: ohanna m. J Natl Cancer Inst. 2017 Aug 1;109(8). doi: 10.1093/jnci/djw340. J Natl Cancer Inst. 2017. PMID: 28376192 Free article.
Rapid decay of engulfed extracellular miRNA by XRN1 exonuclease promotes transient epithelial-mesenchymal transition.
Zangari J, Ilie M, Rouaud F, Signetti L, Ohanna M, Didier R, Roméo B, Goldoni D, Nottet N, Staedel C, Gal J, Mari B, Mograbi B, Hofman P, Brest P. Zangari J, et al. Among authors: ohanna m. Nucleic Acids Res. 2018 Apr 20;46(7):3813-3814. doi: 10.1093/nar/gky213. Nucleic Acids Res. 2018. PMID: 29562367 Free PMC article. No abstract available.
E2F1 inhibition mediates cell death of metastatic melanoma.
Rouaud F, Hamouda-Tekaya N, Cerezo M, Abbe P, Zangari J, Hofman V, Ohanna M, Mograbi B, El-Hachem N, Benfodda Z, Lebeau A, Tulic MK, Hofman P, Bertolotto C, Passeron T, Annicotte JS, Ballotti R, Rocchi S. Rouaud F, et al. Among authors: ohanna m. Cell Death Dis. 2018 May 1;9(5):527. doi: 10.1038/s41419-018-0566-1. Cell Death Dis. 2018. PMID: 29743521 Free PMC article.
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