Konno H - Search Results

1

Pro-inflammation Associated with a Gain-of-Function Mutation (R284S) in the Innate Immune Sensor STING.

Konno H, Chinn IK, Hong D, Orange JS, Lupski JR, Mendoza A, Pedroza LA, Barber GN. Konno H, et al. Cell Rep. 2018 Apr 24;23(4):1112-1123. doi: 10.1016/j.celrep.2018.03.115. Cell Rep. 2018. PMID: 29694889 Free PMC article.

2

Cyclic dinucleotides trigger ULK1 (ATG1) phosphorylation of STING to prevent sustained innate immune signaling.

Konno H, Konno K, Barber GN. Konno H, et al. Among authors: konno k. Cell. 2013 Oct 24;155(3):688-98. doi: 10.1016/j.cell.2013.09.049. Epub 2013 Oct 10. Cell. 2013. PMID: 24119841 Free PMC article.

3

The STING controlled cytosolic-DNA activated innate immune pathway and microbial disease.

Konno H, Barber GN. Konno H, et al. Microbes Infect. 2014 Dec;16(12):998-1001. doi: 10.1016/j.micinf.2014.10.002. Epub 2014 Oct 18. Microbes Infect. 2014. PMID: 25449752 Free PMC article. Review.

4

Deregulation of STING Signaling in Colorectal Carcinoma Constrains DNA Damage Responses and Correlates With Tumorigenesis.

Xia T, Konno H, Ahn J, Barber GN. Xia T, et al. Among authors: konno h. Cell Rep. 2016 Jan 12;14(2):282-97. doi: 10.1016/j.celrep.2015.12.029. Epub 2015 Dec 31. Cell Rep. 2016. PMID: 26748708 Free PMC article.

5

Diverse roles of STING-dependent signaling on the development of cancer.

Ahn J, Konno H, Barber GN. Ahn J, et al. Among authors: konno h. Oncogene. 2015 Oct 8;34(41):5302-8. doi: 10.1038/onc.2014.457. Epub 2015 Feb 2. Oncogene. 2015. PMID: 25639870 Free PMC article.

6

STING recognition of cytoplasmic DNA instigates cellular defense.

Abe T, Harashima A, Xia T, Konno H, Konno K, Morales A, Ahn J, Gutman D, Barber GN. Abe T, et al. Among authors: konno k, konno h. Mol Cell. 2013 Apr 11;50(1):5-15. doi: 10.1016/j.molcel.2013.01.039. Epub 2013 Mar 7. Mol Cell. 2013. PMID: 23478444 Free PMC article.

7

Inflammation-driven carcinogenesis is mediated through STING.

Ahn J, Xia T, Konno H, Konno K, Ruiz P, Barber GN. Ahn J, et al. Among authors: konno k, konno h. Nat Commun. 2014 Oct 10;5:5166. doi: 10.1038/ncomms6166. Nat Commun. 2014. PMID: 25300616 Free PMC article.

8

Recurrent Loss of STING Signaling in Melanoma Correlates with Susceptibility to Viral Oncolysis.

Xia T, Konno H, Barber GN. Xia T, et al. Among authors: konno h. Cancer Res. 2016 Nov 15;76(22):6747-6759. doi: 10.1158/0008-5472.CAN-16-1404. Epub 2016 Sep 28. Cancer Res. 2016. PMID: 27680683

9

Ubiquitination of STING at lysine 224 controls IRF3 activation.

Ni G, Konno H, Barber GN. Ni G, et al. Among authors: konno h. Sci Immunol. 2017 May 5;2(11):eaah7119. doi: 10.1126/sciimmunol.aah7119. Sci Immunol. 2017. PMID: 28763789 Free PMC article.

10

Suppression of STING signaling through epigenetic silencing and missense mutation impedes DNA damage mediated cytokine production.

Konno H, Yamauchi S, Berglund A, Putney RM, Mulé JJ, Barber GN. Konno H, et al. Oncogene. 2018 Apr;37(15):2037-2051. doi: 10.1038/s41388-017-0120-0. Epub 2018 Jan 25. Oncogene. 2018. PMID: 29367762 Free PMC article.

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