Lin G - Search Results

1

Ari-1 Regulates Myonuclear Organization Together with Parkin and Is Associated with Aortic Aneurysms.

Tan KL, Haelterman NA, Kwartler CS, Regalado ES, Lee PT, Nagarkar-Jaiswal S, Guo DC, Duraine L, Wangler MF; University of Washington Center for Mendelian Genomics; Bamshad MJ, Nickerson DA, Lin G, Milewicz DM, Bellen HJ. Tan KL, et al. Among authors: lin g. Dev Cell. 2018 Apr 23;45(2):226-244.e8. doi: 10.1016/j.devcel.2018.03.020. Dev Cell. 2018. PMID: 29689197 Free PMC article.

2

Ubr3, a Novel Modulator of Hh Signaling Affects the Degradation of Costal-2 and Kif7 through Poly-ubiquitination.

Li T, Fan J, Blanco-Sánchez B, Giagtzoglou N, Lin G, Yamamoto S, Jaiswal M, Chen K, Zhang J, Wei W, Lewis MT, Groves AK, Westerfield M, Jia J, Bellen HJ. Li T, et al. Among authors: lin g. PLoS Genet. 2016 May 19;12(5):e1006054. doi: 10.1371/journal.pgen.1006054. eCollection 2016 May. PLoS Genet. 2016. PMID: 27195754 Free PMC article.

3

Loss of Frataxin induces iron toxicity, sphingolipid synthesis, and Pdk1/Mef2 activation, leading to neurodegeneration.

Chen K, Lin G, Haelterman NA, Ho TS, Li T, Li Z, Duraine L, Graham BH, Jaiswal M, Yamamoto S, Rasband MN, Bellen HJ. Chen K, et al. Among authors: lin g. Elife. 2016 Jun 25;5:e16043. doi: 10.7554/eLife.16043. Elife. 2016. PMID: 27343351 Free PMC article.

4

Loss of Frataxin activates the iron/sphingolipid/PDK1/Mef2 pathway in mammals.

Chen K, Ho TS, Lin G, Tan KL, Rasband MN, Bellen HJ. Chen K, et al. Among authors: lin g. Elife. 2016 Nov 30;5:e20732. doi: 10.7554/eLife.20732. Elife. 2016. PMID: 27901468 Free PMC article.

5

Amyotrophic Lateral Sclerosis Pathogenesis Converges on Defects in Protein Homeostasis Associated with TDP-43 Mislocalization and Proteasome-Mediated Degradation Overload.

Lin G, Mao D, Bellen HJ. Lin G, et al. Curr Top Dev Biol. 2017;121:111-171. doi: 10.1016/bs.ctdb.2016.07.004. Epub 2016 Aug 13. Curr Top Dev Biol. 2017. PMID: 28057298 Review.

6

A kinase-dependent feedforward loop affects CREBB stability and long term memory formation.

Lee PT, Lin G, Lin WW, Diao F, White BH, Bellen HJ. Lee PT, et al. Among authors: lin ww, lin g. Elife. 2018 Feb 23;7:e33007. doi: 10.7554/eLife.33007. Elife. 2018. PMID: 29473541 Free PMC article.

7

Phospholipase PLA2G6, a Parkinsonism-Associated Gene, Affects Vps26 and Vps35, Retromer Function, and Ceramide Levels, Similar to α-Synuclein Gain.

Lin G, Lee PT, Chen K, Mao D, Tan KL, Zuo Z, Lin WW, Wang L, Bellen HJ. Lin G, et al. Among authors: lin ww. Cell Metab. 2018 Oct 2;28(4):605-618.e6. doi: 10.1016/j.cmet.2018.05.019. Epub 2018 Jun 14. Cell Metab. 2018. PMID: 29909971 Free article.

8

Sphingolipids in the Pathogenesis of Parkinson's Disease and Parkinsonism.

Lin G, Wang L, Marcogliese PC, Bellen HJ. Lin G, et al. Trends Endocrinol Metab. 2019 Feb;30(2):106-117. doi: 10.1016/j.tem.2018.11.003. Epub 2018 Dec 6. Trends Endocrinol Metab. 2019. PMID: 30528460 Review.

9

VAMP associated proteins are required for autophagic and lysosomal degradation by promoting a PtdIns4P-mediated endosomal pathway.

Mao D, Lin G, Tepe B, Zuo Z, Tan KL, Senturk M, Zhang S, Arenkiel BR, Sardiello M, Bellen HJ. Mao D, et al. Among authors: lin g. Autophagy. 2019 Jul;15(7):1214-1233. doi: 10.1080/15548627.2019.1580103. Epub 2019 Feb 20. Autophagy. 2019. PMID: 30741620 Free PMC article.

10

Ubiquilins regulate autophagic flux through mTOR signalling and lysosomal acidification.

Şentürk M, Lin G, Zuo Z, Mao D, Watson E, Mikos AG, Bellen HJ. Şentürk M, et al. Among authors: lin g. Nat Cell Biol. 2019 Mar;21(3):384-396. doi: 10.1038/s41556-019-0281-x. Epub 2019 Feb 25. Nat Cell Biol. 2019. PMID: 30804504 Free PMC article.

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