Bruno R - Search Results

1

A Model of Overall Survival Predicts Treatment Outcomes with Atezolizumab versus Chemotherapy in Non-Small Cell Lung Cancer Based on Early Tumor Kinetics.

Claret L, Jin JY, Ferté C, Winter H, Girish S, Stroh M, He P, Ballinger M, Sandler A, Joshi A, Rittmeyer A, Gandara D, Soria JC, Bruno R. Claret L, et al. Among authors: bruno r. Clin Cancer Res. 2018 Jul 15;24(14):3292-3298. doi: 10.1158/1078-0432.CCR-17-3662. Epub 2018 Apr 23. Clin Cancer Res. 2018. PMID: 29685883

2

Phase I and pharmacokinetic study of docetaxel and irinotecan in patients with advanced solid tumors.

Couteau C, Risse ML, Ducreux M, Lefresne-Soulas F, Riva A, Lebecq A, Ruffié P, Rougier P, Lokiec F, Bruno R, Armand JP. Couteau C, et al. Among authors: bruno r. J Clin Oncol. 2000 Oct 15;18(20):3545-52. doi: 10.1200/JCO.2000.18.20.3545. J Clin Oncol. 2000. PMID: 11032597 Clinical Trial.

3

Alpha-1-acid glycoprotein as an independent predictor for treatment effects and a prognostic factor of survival in patients with non-small cell lung cancer treated with docetaxel.

Bruno R, Olivares R, Berille J, Chaikin P, Vivier N, Hammershaimb L, Rhodes GR, Rigas JR. Bruno R, et al. Clin Cancer Res. 2003 Mar;9(3):1077-82. Clin Cancer Res. 2003. PMID: 12631610 Clinical Trial.

4

Population pharmacokinetics of efalizumab (humanized monoclonal anti-CD11a antibody) following long-term subcutaneous weekly dosing in psoriasis subjects.

Sun YN, Lu JF, Joshi A, Compton P, Kwon P, Bruno RA. Sun YN, et al. J Clin Pharmacol. 2005 Apr;45(4):468-76. doi: 10.1177/0091270004272731. J Clin Pharmacol. 2005. PMID: 15778428

5

Modeling and simulation of sexual activity daily diary data of patients with female sexual arousal disorder treated with sildenafil citrate (Viagra).

Claret L, Cox EH, McFadyen L, Pidgen A, Johnson PJ, Haughie S, Boolell M, Bruno R. Claret L, et al. Among authors: bruno r. Pharm Res. 2006 Aug;23(8):1756-64. doi: 10.1007/s11095-006-9007-4. Pharm Res. 2006. PMID: 16841199 Clinical Trial.

6

On the use of change in tumor size to predict survival in clinical oncology studies: toward a new paradigm to design and evaluate phase II studies.

Bruno R, Claret L. Bruno R, et al. Clin Pharmacol Ther. 2009 Aug;86(2):136-8. doi: 10.1038/clpt.2009.97. Clin Pharmacol Ther. 2009. PMID: 19621009

7

Model-based prediction of phase III overall survival in colorectal cancer on the basis of phase II tumor dynamics.

Claret L, Girard P, Hoff PM, Van Cutsem E, Zuideveld KP, Jorga K, Fagerberg J, Bruno R. Claret L, et al. Among authors: bruno r. J Clin Oncol. 2009 Sep 1;27(25):4103-8. doi: 10.1200/JCO.2008.21.0807. Epub 2009 Jul 27. J Clin Oncol. 2009. PMID: 19636014

8

A modeling and simulation framework to support early clinical drug development decisions in oncology.

Bruno R, Lu JF, Sun YN, Claret L. Bruno R, et al. J Clin Pharmacol. 2011 Jan;51(1):6-8. doi: 10.1177/0091270010376970. Epub 2010 Jul 13. J Clin Pharmacol. 2011. PMID: 20628172 No abstract available.

9

Population pharmacokinetic/pharmacodynamic modeling for the time course of tumor shrinkage by motesanib in thyroid cancer patients.

Lu JF, Claret L, Sutjandra L, Kuchimanchi M, Melara R, Bruno R, Sun YN. Lu JF, et al. Among authors: bruno r. Cancer Chemother Pharmacol. 2010 Nov;66(6):1151-8. doi: 10.1007/s00280-010-1456-0. Epub 2010 Sep 25. Cancer Chemother Pharmacol. 2010. PMID: 20872145

10

Development of a modeling framework to simulate efficacy endpoints for motesanib in patients with thyroid cancer.

Claret L, Lu JF, Sun YN, Bruno R. Claret L, et al. Among authors: bruno r. Cancer Chemother Pharmacol. 2010 Nov;66(6):1141-9. doi: 10.1007/s00280-010-1449-z. Epub 2010 Sep 25. Cancer Chemother Pharmacol. 2010. PMID: 20872147

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