Wang JX - Search Results

1

Design, synthesis and biological evaluation of novel xanthine oxidase inhibitors bearing a 2-arylbenzo[b]furan scaffold.

Tang HJ, Li W, Zhou M, Peng LY, Wang JX, Li JH, Chen J. Tang HJ, et al. Among authors: wang jx. Eur J Med Chem. 2018 May 10;151:849-860. doi: 10.1016/j.ejmech.2018.01.096. Epub 2018 Feb 2. Eur J Med Chem. 2018. PMID: 29684895

2

Synthesis and anti-hepatitis B virus evaluation of novel ethyl 6-hydroxyquinoline-3-carboxylates in vitro.

Liu Y, Zhao Y, Zhai X, Feng X, Wang J, Gong P. Liu Y, et al. Bioorg Med Chem. 2008 Jul 1;16(13):6522-7. doi: 10.1016/j.bmc.2008.05.029. Epub 2008 May 17. Bioorg Med Chem. 2008. PMID: 18524601

3

Studies on chemical structure modification and biology of a natural product, gambogic acid (I): Synthesis and biological evaluation of oxidized analogues of gambogic acid.

Wang J, Zhao L, Hu Y, Guo Q, Zhang L, Wang X, Li N, You Q. Wang J, et al. Eur J Med Chem. 2009 Jun;44(6):2611-20. doi: 10.1016/j.ejmech.2008.09.034. Epub 2008 Oct 7. Eur J Med Chem. 2009. PMID: 18996626

4

Studies on chemical modification and biology of a natural product, gambogic acid (II): Synthesis and bioevaluation of gambogellic acid and its derivatives from gambogic acid as antitumor agents.

Wang J, Ma J, You Q, Zhao L, Wang F, Li C, Guo Q. Wang J, et al. Eur J Med Chem. 2010 Sep;45(9):4343-53. doi: 10.1016/j.ejmech.2010.04.037. Epub 2010 May 13. Eur J Med Chem. 2010. PMID: 20605273

5

Synthesis and evaluation of xanthine oxidase inhibitory and antioxidant activities of 2-arylbenzo[b]furan derivatives based on salvianolic acid C.

Tang HJ, Zhang XW, Yang L, Li W, Li JH, Wang JX, Chen J. Tang HJ, et al. Among authors: wang jx. Eur J Med Chem. 2016 Nov 29;124:637-648. doi: 10.1016/j.ejmech.2016.08.019. Epub 2016 Aug 31. Eur J Med Chem. 2016. PMID: 27614410

6

Synthesis and biological evaluation of tanshinone IIA derivatives as novel endothelial protective agents.

Bi X, Zhang K, He L, Gao B, Gu Q, Li X, Chen J, Wang J. Bi X, et al. Future Med Chem. 2017 Jun;9(10):1073-1085. doi: 10.4155/fmc-2016-0241. Epub 2017 Jun 20. Future Med Chem. 2017. PMID: 28632415

7

Synthesis and evaluation of xanthone derivatives as acid sphingomyelinase inhibitors: potential treatment for UV-induced skin damage.

Yang K, Gao B, Ming X, Huang Z, Wang M, Dong J, Wang J. Yang K, et al. Future Med Chem. 2017 Oct;9(16):1887-1898. doi: 10.4155/fmc-2017-0102. Epub 2017 Oct 27. Future Med Chem. 2017. PMID: 29076348

8

Synthesis and biological evaluation of novel tanshinone IIA derivatives for treating pain.

Li QN, Huang ZP, Gu QL, Zhi ZE, Yang YH, He L, Chen KL, Wang JX. Li QN, et al. Among authors: wang jx. Chin J Nat Med. 2018 Feb;16(2):113-124. doi: 10.1016/S1875-5364(18)30037-2. Chin J Nat Med. 2018. PMID: 29455726

9

Discovery of N-hydroxy-3-alkoxybenzamides as direct acid sphingomyelinase inhibitors using a ligand-based pharmacophore model.

Yang K, Nong K, Gu Q, Dong J, Wang J. Yang K, et al. Eur J Med Chem. 2018 May 10;151:389-400. doi: 10.1016/j.ejmech.2018.03.065. Epub 2018 Mar 27. Eur J Med Chem. 2018. PMID: 29649738

10

Discovery of Potent, Selective, and Direct Acid Sphingomyelinase Inhibitors with Antidepressant Activity.

Yang K, Yu J, Nong K, Wang Y, Niu A, Chen W, Dong J, Wang J. Yang K, et al. J Med Chem. 2020 Feb 13;63(3):961-974. doi: 10.1021/acs.jmedchem.9b00739. Epub 2020 Jan 28. J Med Chem. 2020. PMID: 31944697

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