Kon OL - Search Results

1

Durable engraftment of genetically modified FVIII-secreting autologous bone marrow stromal cells in the intramedullary microenvironment.

Lee SS, Sivalingam J, Nirmal AJ, Ng WH, Kee I, Song IC, Kiong CY, Gales KA, Chua F, Pena EM, Ogden BE, Kon OL. Lee SS, et al. Among authors: kon ol. J Cell Mol Med. 2018 Jul;22(7):3698-3702. doi: 10.1111/jcmm.13648. Epub 2018 Apr 23. J Cell Mol Med. 2018. PMID: 29682884 Free PMC article.

2

Biosafety assessment of site-directed transgene integration in human umbilical cord-lining cells.

Sivalingam J, Krishnan S, Ng WH, Lee SS, Phan TT, Kon OL. Sivalingam J, et al. Among authors: kon ol. Mol Ther. 2010 Jul;18(7):1346-56. doi: 10.1038/mt.2010.61. Epub 2010 Apr 27. Mol Ther. 2010. PMID: 20424600 Free PMC article.

3

Characterization of Insulin-Secreting Porcine Bone Marrow Stromal Cells Ex Vivo and Autologous Cell Therapy In Vivo.

Do HV, Loke WT, Kee I, Liang V, David SJ, Gan SU, Lee SS, Ng WH, Koong HN, Ong HS, Lee KO, Calne RY, Kon OL. Do HV, et al. Among authors: kon ol. Cell Transplant. 2015;24(7):1205-20. doi: 10.3727/096368914X679363. Epub 2014 Mar 24. Cell Transplant. 2015. PMID: 24667101 Free article.

4

Multidimensional Genome-wide Analyses Show Accurate FVIII Integration by ZFN in Primary Human Cells.

Sivalingam J, Kenanov D, Han H, Nirmal AJ, Ng WH, Lee SS, Masilamani J, Phan TT, Maurer-Stroh S, Kon OL. Sivalingam J, et al. Among authors: kon ol. Mol Ther. 2016 Mar;24(3):607-19. doi: 10.1038/mt.2015.223. Epub 2015 Dec 22. Mol Ther. 2016. PMID: 26689265 Free PMC article.

5

Integrated Multimodal Evaluation of Genotoxicity in ZFN-Modified Primary Human Cells.

Sivalingam J, Kenanov D, Ng WH, Lee SS, Phan TT, Maurer-Stroh S, Kon OL. Sivalingam J, et al. Among authors: kon ol. Methods Mol Biol. 2018;1867:141-164. doi: 10.1007/978-1-4939-8799-3_11. Methods Mol Biol. 2018. PMID: 30155821

6

Nonvirally modified autologous primary hepatocytes correct diabetes and prevent target organ injury in a large preclinical model.

Chen NK, Wong JS, Kee IH, Lai SH, Thng CH, Ng WH, Ng RT, Tan SY, Lee SY, Tan ME, Sivalingam J, Chow PK, Kon OL. Chen NK, et al. Among authors: kon ol. PLoS One. 2008 Mar 5;3(3):e1734. doi: 10.1371/journal.pone.0001734. PLoS One. 2008. PMID: 18320053 Free PMC article.

7

Global molecular dysfunctions in gastric cancer revealed by an integrated analysis of the phosphoproteome and transcriptome.

Guo T, Lee SS, Ng WH, Zhu Y, Gan CS, Zhu J, Wang H, Huang S, Sze SK, Kon OL. Guo T, et al. Among authors: kon ol. Cell Mol Life Sci. 2011 Jun;68(11):1983-2002. doi: 10.1007/s00018-010-0545-x. Epub 2010 Oct 16. Cell Mol Life Sci. 2011. PMID: 20953656 Free PMC article.

8

Intragenic integration in DLC1 sustains factor VIII expression in primary human cells without insertional oncogenicity.

Sivalingam J, Phan TT, Kon OL. Sivalingam J, et al. Among authors: kon ol. Gene Ther. 2014 Apr;21(4):402-12. doi: 10.1038/gt.2014.11. Epub 2014 Feb 20. Gene Ther. 2014. PMID: 24553346 Free PMC article.

9

Plasmid-electroporated primary hepatocytes acquire quasi-physiological secretion of human insulin and restore euglycemia in diabetic mice.

Chen NK, Sivalingam J, Tan SY, Kon OL. Chen NK, et al. Among authors: kon ol. Gene Ther. 2005 Apr;12(8):655-67. doi: 10.1038/sj.gt.3302446. Gene Ther. 2005. PMID: 15703765

10

Mitochondrial-Targeting MET Kinase Inhibitor Kills Erlotinib-Resistant Lung Cancer Cells.

Yang T, Ng WH, Chen H, Chomchopbun K, Huynh TH, Go ML, Kon OL. Yang T, et al. Among authors: kon ol. ACS Med Chem Lett. 2016 Jun 23;7(8):807-12. doi: 10.1021/acsmedchemlett.6b00223. eCollection 2016 Aug 11. ACS Med Chem Lett. 2016. PMID: 27563407 Free PMC article.

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