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Paracrine roles of cellular senescence in promoting tumourigenesis.
Gonzalez-Meljem JM, Apps JR, Fraser HC, Martinez-Barbera JP. Gonzalez-Meljem JM, et al. Br J Cancer. 2018 May;118(10):1283-1288. doi: 10.1038/s41416-018-0066-1. Epub 2018 Apr 19. Br J Cancer. 2018. PMID: 29670296 Free PMC article. Review.
Stem cells and their role in pituitary tumorigenesis.
Carreno G, Gonzalez-Meljem JM, Haston S, Martinez-Barbera JP. Carreno G, et al. Mol Cell Endocrinol. 2017 Apr 15;445:27-34. doi: 10.1016/j.mce.2016.10.005. Epub 2016 Oct 6. Mol Cell Endocrinol. 2017. PMID: 27720895 Free article. Review.
SWI/SNF regulates a transcriptional program that induces senescence to prevent liver cancer.
Tordella L, Khan S, Hohmeyer A, Banito A, Klotz S, Raguz S, Martin N, Dhamarlingam G, Carroll T, González Meljem JM, Deswal S, Martínez-Barbera JP, García-Escudero R, Zuber J, Zender L, Gil J. Tordella L, et al. Genes Dev. 2016 Oct 1;30(19):2187-2198. doi: 10.1101/gad.286112.116. Epub 2016 Oct 13. Genes Dev. 2016. PMID: 27737960 Free PMC article.
Preclinical transgenic and patient-derived xenograft models recapitulate the radiological features of human adamantinomatous craniopharyngioma.
Boult JKR, Apps JR, Hölsken A, Hutchinson JC, Carreno G, Danielson LS, Smith LM, Bäuerle T, Buslei R, Buchfelder M, Virasami AK, Koers A, Arthurs OJ, Jacques TS, Chesler L, Martinez-Barbera JP, Robinson SP. Boult JKR, et al. Brain Pathol. 2018 Jul;28(4):475-483. doi: 10.1111/bpa.12525. Epub 2017 May 17. Brain Pathol. 2018. PMID: 28481062 Free PMC article.
MAPK pathway control of stem cell proliferation and differentiation in the embryonic pituitary provides insights into the pathogenesis of papillary craniopharyngioma.
Haston S, Pozzi S, Carreno G, Manshaei S, Panousopoulos L, Gonzalez-Meljem JM, Apps JR, Virasami A, Thavaraj S, Gutteridge A, Forshew T, Marais R, Brandner S, Jacques TS, Andoniadou CL, Martinez-Barbera JP. Haston S, et al. Development. 2017 Jun 15;144(12):2141-2152. doi: 10.1242/dev.150490. Epub 2017 May 15. Development. 2017. PMID: 28506993 Free PMC article.
Molecular Analyses Reveal Inflammatory Mediators in the Solid Component and Cyst Fluid of Human Adamantinomatous Craniopharyngioma.
Donson AM, Apps J, Griesinger AM, Amani V, Witt DA, Anderson RCE, Niazi TN, Grant G, Souweidane M, Johnston JM, Jackson EM, Kleinschmidt-DeMasters BK, Handler MH, Tan AC, Gore L, Virasami A, Gonzalez-Meljem JM, Jacques TS, Martinez-Barbera JP, Foreman NK, Hankinson TC; Advancing Treatment for Pediatric Craniopharyngioma Consortium. Donson AM, et al. J Neuropathol Exp Neurol. 2017 Sep 1;76(9):779-788. doi: 10.1093/jnen/nlx061. J Neuropathol Exp Neurol. 2017. PMID: 28859336 Free PMC article.
111 results