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Inhibition of IL-6 signaling significantly reduces primary tumor growth and recurrencies in orthotopic xenograft models of pancreatic cancer.
Goumas FA, Holmer R, Egberts JH, Gontarewicz A, Heneweer C, Geisen U, Hauser C, Mende MM, Legler K, Röcken C, Becker T, Waetzig GH, Rose-John S, Kalthoff H. Goumas FA, et al. Among authors: becker t. Int J Cancer. 2015 Sep 1;137(5):1035-46. doi: 10.1002/ijc.29445. Epub 2015 Jan 29. Int J Cancer. 2015. PMID: 25604508
Cancer cell-autonomous TRAIL-R signaling promotes KRAS-driven cancer progression, invasion, and metastasis.
von Karstedt S, Conti A, Nobis M, Montinaro A, Hartwig T, Lemke J, Legler K, Annewanter F, Campbell AD, Taraborrelli L, Grosse-Wilde A, Coy JF, El-Bahrawy MA, Bergmann F, Koschny R, Werner J, Ganten TM, Schweiger T, Hoetzenecker K, Kenessey I, Hegedüs B, Bergmann M, Hauser C, Egberts JH, Becker T, Röcken C, Kalthoff H, Trauzold A, Anderson KI, Sansom OJ, Walczak H. von Karstedt S, et al. Among authors: becker t. Cancer Cell. 2015 Apr 13;27(4):561-73. doi: 10.1016/j.ccell.2015.02.014. Epub 2015 Apr 2. Cancer Cell. 2015. PMID: 25843002 Free PMC article.
Cytoplasmic TRAIL-R1 is a positive prognostic marker in PDAC.
Gundlach JP, Hauser C, Schlegel FM, Böger C, Röder C, Röcken C, Becker T, Egberts JH, Kalthoff H, Trauzold A. Gundlach JP, et al. Among authors: becker t. BMC Cancer. 2018 Jul 31;18(1):777. doi: 10.1186/s12885-018-4688-8. BMC Cancer. 2018. PMID: 30064384 Free PMC article.
TRAIL-R2 promotes skeletal metastasis in a breast cancer xenograft mouse model.
Fritsche H, Heilmann T, Tower RJ, Hauser C, von Au A, El-Sheikh D, Campbell GM, Alp G, Schewe D, Hübner S, Tiwari S, Kownatzki D, Boretius S, Adam D, Jonat W, Becker T, Glüer CC, Zöller M, Kalthoff H, Schem C, Trauzold A. Fritsche H, et al. Among authors: becker t. Oncotarget. 2015 Apr 20;6(11):9502-16. doi: 10.18632/oncotarget.3321. Oncotarget. 2015. PMID: 25909161 Free PMC article.
Prognostic significance of high mobility group A2 (HMGA2) in pancreatic ductal adenocarcinoma: malignant functions of cytoplasmic HMGA2 expression.
Gundlach JP, Hauser C, Schlegel FM, Willms A, Halske C, Röder C, Krüger S, Röcken C, Becker T, Kalthoff H, Trauzold A. Gundlach JP, et al. Among authors: becker t. J Cancer Res Clin Oncol. 2021 Nov;147(11):3313-3324. doi: 10.1007/s00432-021-03745-w. Epub 2021 Jul 24. J Cancer Res Clin Oncol. 2021. PMID: 34302528 Free PMC article.
TRAIL-Receptor 4 Modulates γδ T Cell-Cytotoxicity Toward Cancer Cells.
Tawfik D, Groth C, Gundlach JP, Peipp M, Kabelitz D, Becker T, Oberg HH, Trauzold A, Wesch D. Tawfik D, et al. Among authors: becker t. Front Immunol. 2019 Aug 28;10:2044. doi: 10.3389/fimmu.2019.02044. eCollection 2019. Front Immunol. 2019. PMID: 31555275 Free PMC article.
2,452 results