Rozen R - Search Results

1

Low Dietary Folate Interacts with MTHFD1 Synthetase Deficiency in Mice, a Model for the R653Q Variant, to Increase Incidence of Developmental Delays and Defects.

Christensen KE, Bahous RH, Hou W, Deng L, Malysheva OV, Arning E, Bottiglieri T, Caudill MA, Jerome-Majewska LA, Rozen R. Christensen KE, et al. Among authors: rozen r. J Nutr. 2018 Apr 1;148(4):501-509. doi: 10.1093/jn/nxy013. J Nutr. 2018. PMID: 29659962 Free article.

2

Seven novel mutations in the methylenetetrahydrofolate reductase gene and genotype/phenotype correlations in severe methylenetetrahydrofolate reductase deficiency.

Goyette P, Frosst P, Rosenblatt DS, Rozen R. Goyette P, et al. Among authors: rozen r. Am J Hum Genet. 1995 May;56(5):1052-9. Am J Hum Genet. 1995. PMID: 7726158 Free PMC article.

3

Genetic polymorphisms in methylenetetrahydrofolate reductase and methionine synthase, folate levels in red blood cells, and risk of neural tube defects.

Christensen B, Arbour L, Tran P, Leclerc D, Sabbaghian N, Platt R, Gilfix BM, Rosenblatt DS, Gravel RA, Forbes P, Rozen R. Christensen B, et al. Among authors: rozen r. Am J Med Genet. 1999 May 21;84(2):151-7. doi: 10.1002/(sici)1096-8628(19990521)84:2<151::aid-ajmg12>3.0.co;2-t. Am J Med Genet. 1999. PMID: 10323741

4

Influence of methylenetetrahydrofolate reductase genotype, age, vitamin B-12, and folate status on plasma homocysteine in children.

Delvin EE, Rozen R, Merouani A, Genest J Jr, Lambert M. Delvin EE, et al. Among authors: rozen r. Am J Clin Nutr. 2000 Dec;72(6):1469-73. doi: 10.1093/ajcn/72.6.1469. Am J Clin Nutr. 2000. PMID: 11101473 Clinical Trial.

5

Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition.

Chen Z, Karaplis AC, Ackerman SL, Pogribny IP, Melnyk S, Lussier-Cacan S, Chen MF, Pai A, John SW, Smith RS, Bottiglieri T, Bagley P, Selhub J, Rudnicki MA, James SJ, Rozen R. Chen Z, et al. Among authors: rozen r. Hum Mol Genet. 2001 Mar 1;10(5):433-43. doi: 10.1093/hmg/10.5.433. Hum Mol Genet. 2001. PMID: 11181567

6

Studies of methionine cycle intermediates (SAM, SAH), DNA methylation and the impact of folate deficiency on tumor numbers in Min mice.

Sibani S, Melnyk S, Pogribny IP, Wang W, Hiou-Tim F, Deng L, Trasler J, James SJ, Rozen R. Sibani S, et al. Among authors: rozen r. Carcinogenesis. 2002 Jan;23(1):61-5. doi: 10.1093/carcin/23.1.61. Carcinogenesis. 2002. PMID: 11756224

7

The curly-tail (ct) mouse, an animal model of neural tube defects, displays altered homocysteine metabolism without folate responsiveness or a defect in Mthfr.

Tran P, Hiou-Tim F, Frosst P, Lussier-Cacan S, Bagley P, Selhub J, Bottiglieri T, Rozen R. Tran P, et al. Among authors: rozen r. Mol Genet Metab. 2002 Aug;76(4):297-304. doi: 10.1016/s1096-7192(02)00108-7. Mol Genet Metab. 2002. PMID: 12208134

8

Impact of Dnmt1 deficiency, with and without low folate diets, on tumor numbers and DNA methylation in Min mice.

Trasler J, Deng L, Melnyk S, Pogribny I, Hiou-Tim F, Sibani S, Oakes C, Li E, James SJ, Rozen R. Trasler J, et al. Among authors: rozen r. Carcinogenesis. 2003 Jan;24(1):39-45. doi: 10.1093/carcin/24.1.39. Carcinogenesis. 2003. PMID: 12538347

9

Spina bifida, folate metabolism, and dietary folate intake in a Northern Canadian aboriginal population.

Arbour L, Christensen B, Delormier T, Platt R, Gilfix B, Forbes P, Kovitch I, Morel J, Rozen R. Arbour L, et al. Among authors: rozen r. Int J Circumpolar Health. 2002 Nov;61(4):341-51. doi: 10.3402/ijch.v61i4.17492. Int J Circumpolar Health. 2002. PMID: 12546192 Free article.

10

Effect of Mthfr genotype on diet-induced hyperhomocysteinemia and vascular function in mice.

Devlin AM, Arning E, Bottiglieri T, Faraci FM, Rozen R, Lentz SR. Devlin AM, et al. Among authors: rozen r. Blood. 2004 Apr 1;103(7):2624-9. doi: 10.1182/blood-2003-09-3078. Epub 2003 Nov 20. Blood. 2004. PMID: 14630804 Free article.

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