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Page 1
Tropism for tuft cells determines immune promotion of norovirus pathogenesis.
Wilen CB, Lee S, Hsieh LL, Orchard RC, Desai C, Hykes BL Jr, McAllaster MR, Balce DR, Feehley T, Brestoff JR, Hickey CA, Yokoyama CC, Wang YT, MacDuff DA, Kreamalmayer D, Howitt MR, Neil JA, Cadwell K, Allen PM, Handley SA, van Lookeren Campagne M, Baldridge MT, Virgin HW. Wilen CB, et al. Among authors: neil ja. Science. 2018 Apr 13;360(6385):204-208. doi: 10.1126/science.aar3799. Science. 2018. PMID: 29650672 Free PMC article.
Autophagy protein ATG16L1 prevents necroptosis in the intestinal epithelium.
Matsuzawa-Ishimoto Y, Shono Y, Gomez LE, Hubbard-Lucey VM, Cammer M, Neil J, Dewan MZ, Lieberman SR, Lazrak A, Marinis JM, Beal A, Harris PA, Bertin J, Liu C, Ding Y, van den Brink MRM, Cadwell K. Matsuzawa-Ishimoto Y, et al. J Exp Med. 2017 Dec 4;214(12):3687-3705. doi: 10.1084/jem.20170558. Epub 2017 Oct 31. J Exp Med. 2017. PMID: 29089374 Free PMC article.
The Intestinal Virome and Immunity.
Neil JA, Cadwell K. Neil JA, et al. J Immunol. 2018 Sep 15;201(6):1615-1624. doi: 10.4049/jimmunol.1800631. J Immunol. 2018. PMID: 30181300 Free PMC article. Review.
IFN-I and IL-22 mediate protective effects of intestinal viral infection.
Neil JA, Matsuzawa-Ishimoto Y, Kernbauer-Hölzl E, Schuster SL, Sota S, Venzon M, Dallari S, Galvao Neto A, Hine A, Hudesman D, Loke P, Nice TJ, Cadwell K. Neil JA, et al. Nat Microbiol. 2019 Oct;4(10):1737-1749. doi: 10.1038/s41564-019-0470-1. Epub 2019 Jun 10. Nat Microbiol. 2019. PMID: 31182797 Free PMC article.
The γδ IEL effector API5 masks genetic susceptibility to Paneth cell death.
Matsuzawa-Ishimoto Y, Yao X, Koide A, Ueberheide BM, Axelrad JE, Reis BS, Parsa R, Neil JA, Devlin JC, Rudensky E, Dewan MZ, Cammer M, Blumberg RS, Ding Y, Ruggles KV, Mucida D, Koide S, Cadwell K. Matsuzawa-Ishimoto Y, et al. Among authors: neil ja. Nature. 2022 Oct;610(7932):547-554. doi: 10.1038/s41586-022-05259-y. Epub 2022 Oct 5. Nature. 2022. PMID: 36198790 Free PMC article.
An intestinal organoid-based platform that recreates susceptibility to T-cell-mediated tissue injury.
Matsuzawa-Ishimoto Y, Hine A, Shono Y, Rudensky E, Lazrak A, Yeung F, Neil JA, Yao X, Chen YH, Heaney T, Schuster SL, Zwack EE, Axelrad JE, Hudesman D, Tsai JJ, Nichols K, Dewan MZ, Cammer M, Beal A, Hoffman S, Geddes B, Bertin J, Liu C, Torres VJ, Loke P, van den Brink MRM, Cadwell K. Matsuzawa-Ishimoto Y, et al. Among authors: neil ja. Blood. 2020 Jun 25;135(26):2388-2401. doi: 10.1182/blood.2019004116. Blood. 2020. PMID: 32232483 Free PMC article.
SARS-CoV-2 infection results in immune responses in the respiratory tract and peripheral blood that suggest mechanisms of disease severity.
Zhang W, Chua BY, Selva KJ, Kedzierski L, Ashhurst TM, Haycroft ER, Shoffner-Beck SK, Hensen L, Boyd DF, James F, Mouhtouris E, Kwong JC, Chua KYL, Drewett G, Copaescu A, Dobson JE, Rowntree LC, Habel JR, Allen LF, Koay HF, Neil JA, Gartner MJ, Lee CY, Andersson P, Khan SF, Blakeway L, Wisniewski J, McMahon JH, Vine EE, Cunningham AL, Audsley J, Thevarajan I, Seemann T, Sherry NL, Amanat F, Krammer F, Londrigan SL, Wakim LM, King NJC, Godfrey DI, Mackay LK, Thomas PG, Nicholson S, Arnold KB, Chung AW, Holmes NE, Smibert OC, Trubiano JA, Gordon CL, Nguyen THO, Kedzierska K. Zhang W, et al. Among authors: neil ja. Nat Commun. 2022 May 19;13(1):2774. doi: 10.1038/s41467-022-30088-y. Nat Commun. 2022. PMID: 35589689 Free PMC article.
64 results