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TMEM59 potentiates Wnt signaling by promoting signalosome formation.
Gerlach JP, Jordens I, Tauriello DVF, van 't Land-Kuper I, Bugter JM, Noordstra I, van der Kooij J, Low TY, Pimentel-Muiños FX, Xanthakis D, Fenderico N, Rabouille C, Heck AJR, Egan DA, Maurice MM. Gerlach JP, et al. Among authors: egan da. Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E3996-E4005. doi: 10.1073/pnas.1721321115. Epub 2018 Apr 9. Proc Natl Acad Sci U S A. 2018. PMID: 29632210 Free PMC article.
Aurora A, MCAK, and Kif18b promote Eg5-independent spindle formation.
van Heesbeen RGHP, Raaijmakers JA, Tanenbaum ME, Halim VA, Lelieveld D, Lieftink C, Heck AJR, Egan DA, Medema RH. van Heesbeen RGHP, et al. Among authors: egan da. Chromosoma. 2017 Aug;126(4):473-486. doi: 10.1007/s00412-016-0607-4. Epub 2016 Jun 29. Chromosoma. 2017. PMID: 27354041 Free PMC article.
Boronic acid-based inhibitor of autotaxin reveals rapid turnover of LPA in the circulation.
Albers HM, Dong A, van Meeteren LA, Egan DA, Sunkara M, van Tilburg EW, Schuurman K, van Tellingen O, Morris AJ, Smyth SS, Moolenaar WH, Ovaa H. Albers HM, et al. Among authors: egan da. Proc Natl Acad Sci U S A. 2010 Apr 20;107(16):7257-62. doi: 10.1073/pnas.1001529107. Epub 2010 Apr 1. Proc Natl Acad Sci U S A. 2010. PMID: 20360563 Free PMC article.
HC StratoMineR: A Web-Based Tool for the Rapid Analysis of High-Content Datasets.
Omta WA, van Heesbeen RG, Pagliero RJ, van der Velden LM, Lelieveld D, Nellen M, Kramer M, Yeong M, Saeidi AM, Medema RH, Spruit M, Brinkkemper S, Klumperman J, Egan DA. Omta WA, et al. Among authors: egan da. Assay Drug Dev Technol. 2016 Oct;14(8):439-452. doi: 10.1089/adt.2016.726. Epub 2016 Sep 16. Assay Drug Dev Technol. 2016. PMID: 27636821
Combining Supervised and Unsupervised Machine Learning Methods for Phenotypic Functional Genomics Screening.
Omta WA, van Heesbeen RG, Shen I, de Nobel J, Robers D, van der Velden LM, Medema RH, Siebes APJM, Feelders AJ, Brinkkemper S, Klumperman JS, Spruit MR, Brinkhuis MJS, Egan DA. Omta WA, et al. Among authors: egan da. SLAS Discov. 2020 Jul;25(6):655-664. doi: 10.1177/2472555220919345. Epub 2020 May 13. SLAS Discov. 2020. PMID: 32400262 Free article.
Screening of a Library of FDA-Approved Drugs Identifies Several Enterovirus Replication Inhibitors That Target Viral Protein 2C.
Ulferts R, de Boer SM, van der Linden L, Bauer L, Lyoo HR, Maté MJ, Lichière J, Canard B, Lelieveld D, Omta W, Egan D, Coutard B, van Kuppeveld FJ. Ulferts R, et al. Antimicrob Agents Chemother. 2016 Apr 22;60(5):2627-38. doi: 10.1128/AAC.02182-15. Print 2016 May. Antimicrob Agents Chemother. 2016. PMID: 26856848 Free PMC article.
110 results