Alcazar-Fuoli L - Search Results

1

Insight into the Significance of Aspergillus fumigatus cyp51A Polymorphisms.

Garcia-Rubio R, Alcazar-Fuoli L, Monteiro MC, Monzon S, Cuesta I, Pelaez T, Mellado E. Garcia-Rubio R, et al. Antimicrob Agents Chemother. 2018 May 25;62(6):e00241-18. doi: 10.1128/AAC.00241-18. Print 2018 Jun. Antimicrob Agents Chemother. 2018. PMID: 29632011 Free PMC article.

2

Substitutions at methionine 220 in the 14alpha-sterol demethylase (Cyp51A) of Aspergillus fumigatus are responsible for resistance in vitro to azole antifungal drugs.

Mellado E, Garcia-Effron G, Alcazar-Fuoli L, Cuenca-Estrella M, Rodriguez-Tudela JL. Mellado E, et al. Antimicrob Agents Chemother. 2004 Jul;48(7):2747-50. doi: 10.1128/AAC.48.7.2747-2750.2004. Antimicrob Agents Chemother. 2004. PMID: 15215142 Free PMC article.

3

Combined activity in vitro of caspofungin, amphotericin B, and azole agents against itraconazole-resistant clinical isolates of Aspergillus fumigatus.

Cuenca-Estrella M, Gomez-Lopez A, Garcia-Effron G, Alcazar-Fuoli L, Mellado E, Buitrago MJ, Rodriguez-Tudela JL. Cuenca-Estrella M, et al. Antimicrob Agents Chemother. 2005 Mar;49(3):1232-5. doi: 10.1128/AAC.49.3.1232-1235.2005. Antimicrob Agents Chemother. 2005. PMID: 15728937 Free PMC article.

4

Differences in interactions between azole drugs related to modifications in the 14-alpha sterol demethylase gene (cyp51A) of Aspergillus fumigatus.

Garcia-Effron G, Mellado E, Gomez-Lopez A, Alcazar-Fuoli L, Cuenca-Estrella M, Rodriguez-Tudela JL. Garcia-Effron G, et al. Antimicrob Agents Chemother. 2005 May;49(5):2119-21. doi: 10.1128/AAC.49.5.2119-2121.2005. Antimicrob Agents Chemother. 2005. PMID: 15855543 Free PMC article.

5

Targeted gene disruption of the 14-alpha sterol demethylase (cyp51A) in Aspergillus fumigatus and its role in azole drug susceptibility.

Mellado E, Garcia-Effron G, Buitrago MJ, Alcazar-Fuoli L, Cuenca-Estrella M, Rodriguez-Tudela JL. Mellado E, et al. Antimicrob Agents Chemother. 2005 Jun;49(6):2536-8. doi: 10.1128/AAC.49.6.2536-2538.2005. Antimicrob Agents Chemother. 2005. PMID: 15917566 Free PMC article.

6

Aspergillus fumigatus C-5 sterol desaturases Erg3A and Erg3B: role in sterol biosynthesis and antifungal drug susceptibility.

Alcazar-Fuoli L, Mellado E, Garcia-Effron G, Buitrago MJ, Lopez JF, Grimalt JO, Cuenca-Estrella JM, Rodriguez-Tudela JL. Alcazar-Fuoli L, et al. Antimicrob Agents Chemother. 2006 Feb;50(2):453-60. doi: 10.1128/AAC.50.2.453-460.2006. Antimicrob Agents Chemother. 2006. PMID: 16436696 Free PMC article.

7

A new Aspergillus fumigatus resistance mechanism conferring in vitro cross-resistance to azole antifungals involves a combination of cyp51A alterations.

Mellado E, Garcia-Effron G, Alcázar-Fuoli L, Melchers WJ, Verweij PE, Cuenca-Estrella M, Rodríguez-Tudela JL. Mellado E, et al. Antimicrob Agents Chemother. 2007 Jun;51(6):1897-904. doi: 10.1128/AAC.01092-06. Epub 2007 Mar 19. Antimicrob Agents Chemother. 2007. PMID: 17371828 Free PMC article.

8

Time of incubation for antifungal susceptibility testing of Aspergillus fumigatus: can MIC values be obtained at 24 hours?

Rodriguez-Tudela JL, Alcazar-Fuoli L, Alastruey-Izquierdo A, Monzon A, Mellado E, Cuenca-Estrella M. Rodriguez-Tudela JL, et al. Antimicrob Agents Chemother. 2007 Dec;51(12):4502-4. doi: 10.1128/AAC.00933-07. Epub 2007 Oct 15. Antimicrob Agents Chemother. 2007. PMID: 17938188 Free PMC article.

9

Ergosterol biosynthesis pathway in Aspergillus fumigatus.

Alcazar-Fuoli L, Mellado E, Garcia-Effron G, Lopez JF, Grimalt JO, Cuenca-Estrella JM, Rodriguez-Tudela JL. Alcazar-Fuoli L, et al. Steroids. 2008 Mar;73(3):339-47. doi: 10.1016/j.steroids.2007.11.005. Epub 2007 Dec 3. Steroids. 2008. PMID: 18191972

10

In vitro activities of 35 double combinations of antifungal agents against Scedosporium apiospermum and Scedosporium prolificans.

Cuenca-Estrella M, Alastruey-Izquierdo A, Alcazar-Fuoli L, Bernal-Martinez L, Gomez-Lopez A, Buitrago MJ, Mellado E, Rodriguez-Tudela JL. Cuenca-Estrella M, et al. Antimicrob Agents Chemother. 2008 Mar;52(3):1136-9. doi: 10.1128/AAC.01160-07. Epub 2008 Jan 14. Antimicrob Agents Chemother. 2008. PMID: 18195067 Free PMC article.

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