Wright GD - Search Results

1

Substrate Recognition by a Colistin Resistance Enzyme from Moraxella catarrhalis.

Stogios PJ, Cox G, Zubyk HL, Evdokimova E, Wawrzak Z, Wright GD, Savchenko A. Stogios PJ, et al. Among authors: wright gd. ACS Chem Biol. 2018 May 18;13(5):1322-1332. doi: 10.1021/acschembio.8b00116. Epub 2018 Apr 19. ACS Chem Biol. 2018. PMID: 29631403 Free PMC article.

2

Prodigious substrate specificity of AAC(6')-APH(2"), an aminoglycoside antibiotic resistance determinant in enterococci and staphylococci.

Daigle DM, Hughes DW, Wright GD. Daigle DM, et al. Among authors: wright gd. Chem Biol. 1999 Feb;6(2):99-110. doi: 10.1016/S1074-5521(99)80006-4. Chem Biol. 1999. PMID: 10021417

3

Structure and function of sedoheptulose-7-phosphate isomerase, a critical enzyme for lipopolysaccharide biosynthesis and a target for antibiotic adjuvants.

Taylor PL, Blakely KM, de Leon GP, Walker JR, McArthur F, Evdokimova E, Zhang K, Valvano MA, Wright GD, Junop MS. Taylor PL, et al. Among authors: wright gd. J Biol Chem. 2008 Feb 1;283(5):2835-45. doi: 10.1074/jbc.M706163200. Epub 2007 Dec 3. J Biol Chem. 2008. PMID: 18056714 Free article.

4

Antibiotic resistance by enzyme inactivation: from mechanisms to solutions.

De Pascale G, Wright GD. De Pascale G, et al. Among authors: wright gd. Chembiochem. 2010 Jul 5;11(10):1325-34. doi: 10.1002/cbic.201000067. Chembiochem. 2010. PMID: 20564281 Review. No abstract available.

5

The genomic enzymology of antibiotic resistance.

Morar M, Wright GD. Morar M, et al. Among authors: wright gd. Annu Rev Genet. 2010;44:25-51. doi: 10.1146/annurev-genet-102209-163517. Annu Rev Genet. 2010. PMID: 20822442 Review.

6

Q&A: Antibiotic resistance: where does it come from and what can we do about it?

Wright GD. Wright GD. BMC Biol. 2010 Sep 20;8:123. doi: 10.1186/1741-7007-8-123. BMC Biol. 2010. PMID: 20887638 Free PMC article. No abstract available.

7

Structure and function of APH(4)-Ia, a hygromycin B resistance enzyme.

Stogios PJ, Shakya T, Evdokimova E, Savchenko A, Wright GD. Stogios PJ, et al. Among authors: wright gd. J Biol Chem. 2011 Jan 21;286(3):1966-75. doi: 10.1074/jbc.M110.194266. Epub 2010 Nov 17. J Biol Chem. 2011. PMID: 21084294 Free PMC article.

8

A small molecule discrimination map of the antibiotic resistance kinome.

Shakya T, Stogios PJ, Waglechner N, Evdokimova E, Ejim L, Blanchard JE, McArthur AG, Savchenko A, Wright GD. Shakya T, et al. Among authors: wright gd. Chem Biol. 2011 Dec 23;18(12):1591-601. doi: 10.1016/j.chembiol.2011.10.018. Chem Biol. 2011. PMID: 22195561

9

A forward chemical screen identifies antibiotic adjuvants in Escherichia coli.

Taylor PL, Rossi L, De Pascale G, Wright GD. Taylor PL, et al. Among authors: wright gd. ACS Chem Biol. 2012 Sep 21;7(9):1547-55. doi: 10.1021/cb300269g. Epub 2012 Jun 22. ACS Chem Biol. 2012. PMID: 22698393

10

Inhibition of WTA synthesis blocks the cooperative action of PBPs and sensitizes MRSA to β-lactams.

Farha MA, Leung A, Sewell EW, D'Elia MA, Allison SE, Ejim L, Pereira PM, Pinho MG, Wright GD, Brown ED. Farha MA, et al. Among authors: wright gd. ACS Chem Biol. 2013 Jan 18;8(1):226-33. doi: 10.1021/cb300413m. Epub 2012 Oct 19. ACS Chem Biol. 2013. PMID: 23062620 Free PMC article.

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