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194 results

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Page 1
CNS Langerhans cell histiocytosis: Common hematopoietic origin for LCH-associated neurodegeneration and mass lesions.
McClain KL, Picarsic J, Chakraborty R, Zinn D, Lin H, Abhyankar H, Scull B, Shih A, Lim KPH, Eckstein O, Lubega J, Peters TL, Olea W, Burke T, Ahmed N, Hicks MJ, Tran B, Jones J, Dauser R, Jeng M, Baiocchi R, Schiff D, Goldman S, Heym KM, Wilson H, Carcamo B, Kumar A, Rodriguez-Galindo C, Whipple NS, Campbell P, Murdoch G, Kofler J, Heales S, Malone M, Woltjer R, Quinn JF, Orchard P, Kruer MC, Jaffe R, Manz MG, Lira SA, Parsons DW, Merad M, Man TK, Allen CE. McClain KL, et al. Among authors: parsons dw. Cancer. 2018 Jun 15;124(12):2607-2620. doi: 10.1002/cncr.31348. Epub 2018 Apr 6. Cancer. 2018. PMID: 29624648 Free PMC article.
Mutually exclusive recurrent somatic mutations in MAP2K1 and BRAF support a central role for ERK activation in LCH pathogenesis.
Chakraborty R, Hampton OA, Shen X, Simko SJ, Shih A, Abhyankar H, Lim KP, Covington KR, Trevino L, Dewal N, Muzny DM, Doddapaneni H, Hu J, Wang L, Lupo PJ, Hicks MJ, Bonilla DL, Dwyer KC, Berres ML, Poulikakos PI, Merad M, McClain KL, Wheeler DA, Allen CE, Parsons DW. Chakraborty R, et al. Among authors: parsons dw. Blood. 2014 Nov 6;124(19):3007-15. doi: 10.1182/blood-2014-05-577825. Epub 2014 Sep 8. Blood. 2014. PMID: 25202140 Free PMC article.
BCOR-CCNB3 fusions are frequent in undifferentiated sarcomas of male children.
Peters TL, Kumar V, Polikepahad S, Lin FY, Sarabia SF, Liang Y, Wang WL, Lazar AJ, Doddapaneni H, Chao H, Muzny DM, Wheeler DA, Okcu MF, Plon SE, Hicks MJ, López-Terrada D, Parsons DW, Roy A. Peters TL, et al. Among authors: parsons dw. Mod Pathol. 2015 Apr;28(4):575-86. doi: 10.1038/modpathol.2014.139. Epub 2014 Oct 31. Mod Pathol. 2015. PMID: 25360585 Free PMC article.
Alternative genetic mechanisms of BRAF activation in Langerhans cell histiocytosis.
Chakraborty R, Burke TM, Hampton OA, Zinn DJ, Lim KP, Abhyankar H, Scull B, Kumar V, Kakkar N, Wheeler DA, Roy A, Poulikakos PI, Merad M, McClain KL, Parsons DW, Allen CE. Chakraborty R, et al. Among authors: parsons dw. Blood. 2016 Nov 24;128(21):2533-2537. doi: 10.1182/blood-2016-08-733790. Epub 2016 Oct 11. Blood. 2016. PMID: 27729324 Free PMC article.
Pediatric oncology enters an era of precision medicine.
Seibel NL, Janeway K, Allen CE, Chi SN, Cho YJ, Glade Bender JL, Kim A, Laetsch TW, Irwin MS, Takebe N, Tricoli JV, Parsons DW. Seibel NL, et al. Among authors: parsons dw. Curr Probl Cancer. 2017 May-Jun;41(3):194-200. doi: 10.1016/j.currproblcancer.2017.01.002. Epub 2017 Feb 1. Curr Probl Cancer. 2017. PMID: 28343740
Target and Agent Prioritization for the Children's Oncology Group-National Cancer Institute Pediatric MATCH Trial.
Allen CE, Laetsch TW, Mody R, Irwin MS, Lim MS, Adamson PC, Seibel NL, Parsons DW, Cho YJ, Janeway K; Pediatric MATCH Target and Agent Prioritization Committee. Allen CE, et al. Among authors: parsons dw. J Natl Cancer Inst. 2017 May 1;109(5):djw274. doi: 10.1093/jnci/djw274. J Natl Cancer Inst. 2017. PMID: 28376230 Free PMC article. Clinical Trial.
Activating MAPK1 (ERK2) mutation in an aggressive case of disseminated juvenile xanthogranuloma.
Chakraborty R, Hampton OA, Abhyankar H, Zinn DJ, Grimes A, Skull B, Eckstein O, Mahmood N, Wheeler DA, Lopez-Terrada D, Peters TL, Hicks JM, Elghetany T, Krance R, Poulikakos PI, Merad M, McClain KL, Allen CE, Parsons DW. Chakraborty R, et al. Among authors: parsons dw. Oncotarget. 2017 Jul 11;8(28):46065-46070. doi: 10.18632/oncotarget.17521. Oncotarget. 2017. PMID: 28512266 Free PMC article.
A genome-wide association study of LCH identifies a variant in SMAD6 associated with susceptibility.
Peckham-Gregory EC, Chakraborty R, Scheurer ME, Belmont JW, Abhyankar H, Sengal AG, Scull BP, Eckstein O, Zinn DJ, Mayer L, Shih A, Merad M, Parsons DW, McClain KL, Lupo PJ, Allen CE. Peckham-Gregory EC, et al. Among authors: parsons dw. Blood. 2017 Nov 16;130(20):2229-2232. doi: 10.1182/blood-2017-08-800565. Epub 2017 Sep 21. Blood. 2017. PMID: 28935696 Free PMC article. No abstract available.
194 results