Opitz R - Search Results

1

A Rapid CRISPR/Cas-based Mutagenesis Assay in Zebrafish for Identification of Genes Involved in Thyroid Morphogenesis and Function.

Trubiroha A, Gillotay P, Giusti N, Gacquer D, Libert F, Lefort A, Haerlingen B, De Deken X, Opitz R, Costagliola S. Trubiroha A, et al. Among authors: opitz r. Sci Rep. 2018 Apr 4;8(1):5647. doi: 10.1038/s41598-018-24036-4. Sci Rep. 2018. PMID: 29618800 Free PMC article.

2

TSH receptor function is required for normal thyroid differentiation in zebrafish.

Opitz R, Maquet E, Zoenen M, Dadhich R, Costagliola S. Opitz R, et al. Mol Endocrinol. 2011 Sep;25(9):1579-99. doi: 10.1210/me.2011-0046. Epub 2011 Jul 7. Mol Endocrinol. 2011. PMID: 21737742 Free PMC article.

3

Transgenic zebrafish illuminate the dynamics of thyroid morphogenesis and its relationship to cardiovascular development.

Opitz R, Maquet E, Huisken J, Antonica F, Trubiroha A, Pottier G, Janssens V, Costagliola S. Opitz R, et al. Dev Biol. 2012 Dec 15;372(2):203-16. doi: 10.1016/j.ydbio.2012.09.011. Epub 2012 Sep 26. Dev Biol. 2012. PMID: 23022354 Free article.

4

Generation of functional thyroid from embryonic stem cells.

Antonica F, Kasprzyk DF, Opitz R, Iacovino M, Liao XH, Dumitrescu AM, Refetoff S, Peremans K, Manto M, Kyba M, Costagliola S. Antonica F, et al. Among authors: opitz r. Nature. 2012 Nov 1;491(7422):66-71. doi: 10.1038/nature11525. Epub 2012 Oct 10. Nature. 2012. PMID: 23051751 Free PMC article.

5

New model systems to illuminate thyroid organogenesis. Part I: an update on the zebrafish toolbox.

Opitz R, Antonica F, Costagliola S. Opitz R, et al. Eur Thyroid J. 2013 Dec;2(4):229-42. doi: 10.1159/000357079. Epub 2013 Dec 3. Eur Thyroid J. 2013. PMID: 24783054 Free PMC article. Review.

6

Functional zebrafish studies based on human genotyping point to netrin-1 as a link between aberrant cardiovascular development and thyroid dysgenesis.

Opitz R, Hitz MP, Vandernoot I, Trubiroha A, Abu-Khudir R, Samuels M, Désilets V, Costagliola S, Andelfinger G, Deladoëy J. Opitz R, et al. Endocrinology. 2015 Jan;156(1):377-88. doi: 10.1210/en.2014-1628. Endocrinology. 2015. PMID: 25353184 Free PMC article.

7

The synthetic gestagen levonorgestrel directly affects gene expression in thyroid and pituitary glands of Xenopus laevis tadpoles.

Lorenz C, Opitz R, Trubiroha A, Lutz I, Zikova A, Kloas W. Lorenz C, et al. Among authors: opitz r. Aquat Toxicol. 2016 Aug;177:63-73. doi: 10.1016/j.aquatox.2016.05.011. Epub 2016 May 20. Aquat Toxicol. 2016. PMID: 27262936

8

Small-Molecule Screening in Zebrafish Embryos Identifies Signaling Pathways Regulating Early Thyroid Development.

Haerlingen B, Opitz R, Vandernoot I, Trubiroha A, Gillotay P, Giusti N, Costagliola S. Haerlingen B, et al. Among authors: opitz r. Thyroid. 2019 Nov;29(11):1683-1703. doi: 10.1089/thy.2019.0122. Epub 2019 Oct 8. Thyroid. 2019. PMID: 31507237

9

Inhibition of the thyroid hormonogenic H₂O₂ production by Duox/DuoxA in zebrafish reveals VAS2870 as a new goitrogenic compound.

Giusti N, Gillotay P, Trubiroha A, Opitz R, Dumont JE, Costagliola S, De Deken X. Giusti N, et al. Among authors: opitz r. Mol Cell Endocrinol. 2020 Jan 15;500:110635. doi: 10.1016/j.mce.2019.110635. Epub 2019 Oct 31. Mol Cell Endocrinol. 2020. PMID: 31678421

10

Enhanced Canonical Wnt Signaling During Early Zebrafish Development Perturbs the Interaction of Cardiac Mesoderm and Pharyngeal Endoderm and Causes Thyroid Specification Defects.

Vandernoot I, Haerlingen B, Gillotay P, Trubiroha A, Janssens V, Opitz R, Costagliola S. Vandernoot I, et al. Among authors: opitz r. Thyroid. 2021 Mar;31(3):420-438. doi: 10.1089/thy.2019.0828. Epub 2020 Sep 16. Thyroid. 2021. PMID: 32777984

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