Wang H - Search Results

1

Novel Tadalafil Derivatives Ameliorates Scopolamine-Induced Cognitive Impairment in Mice via Inhibition of Acetylcholinesterase (AChE) and Phosphodiesterase 5 (PDE5).

Ni W, Wang H, Li X, Zheng X, Wang M, Zhang J, Gong Q, Ling D, Mao F, Zhang H, Li J. Ni W, et al. Among authors: wang h, wang m. ACS Chem Neurosci. 2018 Jul 18;9(7):1625-1636. doi: 10.1021/acschemneuro.8b00014. Epub 2018 Apr 17. ACS Chem Neurosci. 2018. PMID: 29616790

2

Development of Multifunctional Pyrimidinylthiourea Derivatives as Potential Anti-Alzheimer Agents.

Li X, Wang H, Lu Z, Zheng X, Ni W, Zhu J, Fu Y, Lian F, Zhang N, Li J, Zhang H, Mao F. Li X, et al. Among authors: wang h. J Med Chem. 2016 Sep 22;59(18):8326-44. doi: 10.1021/acs.jmedchem.6b00636. Epub 2016 Sep 6. J Med Chem. 2016. PMID: 27552582

3

Novel Vilazodone-Tacrine Hybrids as Potential Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease Accompanied with Depression: Design, Synthesis, and Biological Evaluation.

Li X, Wang H, Xu Y, Liu W, Gong Q, Wang W, Qiu X, Zhu J, Mao F, Zhang H, Li J. Li X, et al. Among authors: wang h, wang w. ACS Chem Neurosci. 2017 Dec 20;8(12):2708-2721. doi: 10.1021/acschemneuro.7b00259. Epub 2017 Sep 19. ACS Chem Neurosci. 2017. PMID: 28872831

4

Design, Synthesis, and Biological Evaluation of Orally Available First-Generation Dual-Target Selective Inhibitors of Acetylcholinesterase (AChE) and Phosphodiesterase 5 (PDE5) for the Treatment of Alzheimer's Disease.

Mao F, Wang H, Ni W, Zheng X, Wang M, Bao K, Ling D, Li X, Xu Y, Zhang H, Li J. Mao F, et al. Among authors: wang h, wang m. ACS Chem Neurosci. 2018 Feb 21;9(2):328-345. doi: 10.1021/acschemneuro.7b00345. Epub 2017 Nov 9. ACS Chem Neurosci. 2018. PMID: 29068218

5

Discovery of novel propargylamine-modified 4-aminoalkyl imidazole substituted pyrimidinylthiourea derivatives as multifunctional agents for the treatment of Alzheimer's disease.

Xu YX, Wang H, Li XK, Dong SN, Liu WW, Gong Q, Wang TD, Tang Y, Zhu J, Li J, Zhang HY, Mao F. Xu YX, et al. Among authors: wang h, wang td. Eur J Med Chem. 2018 Jan 1;143:33-47. doi: 10.1016/j.ejmech.2017.08.025. Epub 2017 Aug 10. Eur J Med Chem. 2018. PMID: 29172081

6

Design, synthesis and evaluation of vilazodone-tacrine hybrids as multitarget-directed ligands against depression with cognitive impairment.

Liu W, Wang H, Li X, Xu Y, Zhang J, Wang W, Gong Q, Qiu X, Zhu J, Mao F, Zhang H, Li J. Liu W, et al. Among authors: wang h, wang w. Bioorg Med Chem. 2018 Jul 23;26(12):3117-3125. doi: 10.1016/j.bmc.2018.04.037. Epub 2018 Apr 18. Bioorg Med Chem. 2018. PMID: 29729987

7

Rational Design of Novel Selective Dual-Target Inhibitors of Acetylcholinesterase and Monoamine Oxidase B as Potential Anti-Alzheimer's Disease Agents.

Xu Y, Zhang J, Wang H, Mao F, Bao K, Liu W, Zhu J, Li X, Zhang H, Li J. Xu Y, et al. Among authors: wang h. ACS Chem Neurosci. 2019 Jan 16;10(1):482-496. doi: 10.1021/acschemneuro.8b00357. Epub 2018 Aug 29. ACS Chem Neurosci. 2019. PMID: 30110536

8

Reconsideration of Anticholinesterase Therapeutic Strategies against Alzheimer's Disease.

Wang H, Zhang H. Wang H, et al. ACS Chem Neurosci. 2019 Feb 20;10(2):852-862. doi: 10.1021/acschemneuro.8b00391. Epub 2018 Dec 6. ACS Chem Neurosci. 2019. PMID: 30521323 Review.

9

The novel therapeutic strategy of vilazodone-donepezil chimeras as potent triple-target ligands for the potential treatment of Alzheimer's disease with comorbid depression.

Li X, Li J, Huang Y, Gong Q, Fu Y, Xu Y, Huang J, You H, Zhang D, Zhang D, Mao F, Zhu J, Wang H, Zhang H, Li J. Li X, et al. Among authors: wang h. Eur J Med Chem. 2022 Feb 5;229:114045. doi: 10.1016/j.ejmech.2021.114045. Epub 2021 Dec 7. Eur J Med Chem. 2022. PMID: 34922191

10

Natural β-Dihydroagarofuran-Type Sesquiterpenoids as Cognition-Enhancing and Neuroprotective Agents from Medicinal Plants of the Genus Celastrus.

Ning R, Lei Y, Liu S, Wang H, Zhang R, Wang W, Zhu Y, Zhang H, Zhao W. Ning R, et al. Among authors: wang h, wang w. J Nat Prod. 2015 Sep 25;78(9):2175-86. doi: 10.1021/acs.jnatprod.5b00234. Epub 2015 Aug 21. J Nat Prod. 2015. PMID: 26295746

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