Kristensen C - Search Results

1

Glycoengineering design options for IgG1 in CHO cells using precise gene editing.

Schulz MA, Tian W, Mao Y, Van Coillie J, Sun L, Larsen JS, Chen YH, Kristensen C, Vakhrushev SY, Clausen H, Yang Z. Schulz MA, et al. Among authors: kristensen c. Glycobiology. 2018 Jul 1;28(7):542-549. doi: 10.1093/glycob/cwy022. Glycobiology. 2018. PMID: 29596681

2

Engineered CHO cells for production of diverse, homogeneous glycoproteins.

Yang Z, Wang S, Halim A, Schulz MA, Frodin M, Rahman SH, Vester-Christensen MB, Behrens C, Kristensen C, Vakhrushev SY, Bennett EP, Wandall HH, Clausen H. Yang Z, et al. Among authors: kristensen c. Nat Biotechnol. 2015 Aug;33(8):842-4. doi: 10.1038/nbt.3280. Epub 2015 Jul 20. Nat Biotechnol. 2015. PMID: 26192319

3

The glycosylation design space for recombinant lysosomal replacement enzymes produced in CHO cells.

Tian W, Ye Z, Wang S, Schulz MA, Van Coillie J, Sun L, Chen YH, Narimatsu Y, Hansen L, Kristensen C, Mandel U, Bennett EP, Jabbarzadeh-Tabrizi S, Schiffmann R, Shen JS, Vakhrushev SY, Clausen H, Yang Z. Tian W, et al. Among authors: kristensen c. Nat Commun. 2019 Apr 30;10(1):1785. doi: 10.1038/s41467-019-09809-3. Nat Commun. 2019. PMID: 31040271 Free PMC article.

4

N-glycosylation increases the circulatory half-life of human growth hormone.

Flintegaard TV, Thygesen P, Rahbek-Nielsen H, Levery SB, Kristensen C, Clausen H, Bolt G. Flintegaard TV, et al. Among authors: kristensen c. Endocrinology. 2010 Nov;151(11):5326-36. doi: 10.1210/en.2010-0574. Epub 2010 Sep 8. Endocrinology. 2010. PMID: 20826563

5

Posttranslational N-glycosylation takes place during the normal processing of human coagulation factor VII.

Bolt G, Kristensen C, Steenstrup TD. Bolt G, et al. Among authors: kristensen c. Glycobiology. 2005 May;15(5):541-7. doi: 10.1093/glycob/cwi032. Epub 2004 Dec 22. Glycobiology. 2005. PMID: 15616124

6

Network reconstruction of the mouse secretory pathway applied on CHO cell transcriptome data.

Lund AM, Kaas CS, Brandl J, Pedersen LE, Kildegaard HF, Kristensen C, Andersen MR. Lund AM, et al. Among authors: kristensen c. BMC Syst Biol. 2017 Mar 15;11(1):37. doi: 10.1186/s12918-017-0414-4. BMC Syst Biol. 2017. PMID: 28298216 Free PMC article.

7

Deep sequencing reveals different compositions of mRNA transcribed from the F8 gene in a panel of FVIII-producing CHO cell lines.

Kaas CS, Bolt G, Hansen JJ, Andersen MR, Kristensen C. Kaas CS, et al. Among authors: kristensen c. Biotechnol J. 2015 Jul;10(7):1081-9. doi: 10.1002/biot.201400667. Epub 2015 May 26. Biotechnol J. 2015. PMID: 25963793

8

Sequencing the CHO DXB11 genome reveals regional variations in genomic stability and haploidy.

Kaas CS, Kristensen C, Betenbaugh MJ, Andersen MR. Kaas CS, et al. Among authors: kristensen c. BMC Genomics. 2015 Mar 8;16(1):160. doi: 10.1186/s12864-015-1391-x. BMC Genomics. 2015. PMID: 25887056 Free PMC article.

9

All post-translational modifications except propeptide cleavage are required for optimal secretion of coagulation factor VII.

Bolt G, Steenstrup TD, Kristensen C. Bolt G, et al. Among authors: kristensen c. Thromb Haemost. 2007 Nov;98(5):988-97. doi: 10.1160/th07-05-0332. Thromb Haemost. 2007. PMID: 18000603

10

More than one intracellular processing bottleneck delays the secretion of coagulation factor VII.

Bolt G, Kristensen C, Steenstrup TD. Bolt G, et al. Among authors: kristensen c. Thromb Haemost. 2008 Aug;100(2):204-10. Thromb Haemost. 2008. PMID: 18690338

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