Austin RC - Search Results

1

Loss-of-function PCSK9 mutants evade the unfolded protein response sensor GRP78 and fail to induce endoplasmic reticulum stress when retained.

Lebeau P, Platko K, Al-Hashimi AA, Byun JH, Lhoták Š, Holzapfel N, Gyulay G, Igdoura SA, Cool DR, Trigatti B, Seidah NG, Austin RC. Lebeau P, et al. Among authors: austin rc. J Biol Chem. 2018 May 11;293(19):7329-7343. doi: 10.1074/jbc.RA117.001049. Epub 2018 Mar 28. J Biol Chem. 2018. PMID: 29593095 Free PMC article.

2

Overexpression of the 78-kDa glucose-regulated protein/immunoglobulin-binding protein (GRP78/BiP) inhibits tissue factor procoagulant activity.

Watson LM, Chan AK, Berry LR, Li J, Sood SK, Dickhout JG, Xu L, Werstuck GH, Bajzar L, Klamut HJ, Austin RC. Watson LM, et al. Among authors: austin rc. J Biol Chem. 2003 May 9;278(19):17438-47. doi: 10.1074/jbc.M301006200. Epub 2003 Mar 5. J Biol Chem. 2003. PMID: 12621026 Free article.

3

Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: role of ATP binding site in suppression of caspase-7 activation.

Reddy RK, Mao C, Baumeister P, Austin RC, Kaufman RJ, Lee AS. Reddy RK, et al. Among authors: austin rc. J Biol Chem. 2003 Jun 6;278(23):20915-24. doi: 10.1074/jbc.M212328200. Epub 2003 Mar 28. J Biol Chem. 2003. PMID: 12665508 Free article.

4

TDAG51 is induced by homocysteine, promotes detachment-mediated programmed cell death, and contributes to the cevelopment of atherosclerosis in hyperhomocysteinemia.

Hossain GS, van Thienen JV, Werstuck GH, Zhou J, Sood SK, Dickhout JG, de Koning AB, Tang D, Wu D, Falk E, Poddar R, Jacobsen DW, Zhang K, Kaufman RJ, Austin RC. Hossain GS, et al. Among authors: austin rc. J Biol Chem. 2003 Aug 8;278(32):30317-27. doi: 10.1074/jbc.M212897200. Epub 2003 May 8. J Biol Chem. 2003. PMID: 12738777 Free article.

5

Association of multiple cellular stress pathways with accelerated atherosclerosis in hyperhomocysteinemic apolipoprotein E-deficient mice.

Zhou J, Werstuck GH, Lhoták S, de Koning AB, Sood SK, Hossain GS, Møller J, Ritskes-Hoitinga M, Falk E, Dayal S, Lentz SR, Austin RC. Zhou J, et al. Among authors: austin rc. Circulation. 2004 Jul 13;110(2):207-13. doi: 10.1161/01.CIR.0000134487.51510.97. Epub 2004 Jun 21. Circulation. 2004. PMID: 15210586

6

Activation of the unfolded protein response occurs at all stages of atherosclerotic lesion development in apolipoprotein E-deficient mice.

Zhou J, Lhoták S, Hilditch BA, Austin RC. Zhou J, et al. Among authors: austin rc. Circulation. 2005 Apr 12;111(14):1814-21. doi: 10.1161/01.CIR.0000160864.31351.C1. Epub 2005 Apr 4. Circulation. 2005. PMID: 15809369

7

Peroxynitrite causes endoplasmic reticulum stress and apoptosis in human vascular endothelium: implications in atherogenesis.

Dickhout JG, Hossain GS, Pozza LM, Zhou J, Lhoták S, Austin RC. Dickhout JG, et al. Among authors: austin rc. Arterioscler Thromb Vasc Biol. 2005 Dec;25(12):2623-9. doi: 10.1161/01.ATV.0000189159.96900.d9. Epub 2005 Oct 6. Arterioscler Thromb Vasc Biol. 2005. PMID: 16210571

8

Increased endoplasmic reticulum stress in atherosclerotic plaques associated with acute coronary syndrome: a balancing act between plaque stability and rupture.

Dickhout JG, Colgan SM, Lhoták S, Austin RC. Dickhout JG, et al. Among authors: austin rc. Circulation. 2007 Sep 11;116(11):1214-6. doi: 10.1161/CIRCULATIONAHA.107.728378. Circulation. 2007. PMID: 17846339 No abstract available.

9

Role of endoplasmic reticulum calcium disequilibria in the mechanism of homocysteine-induced ER stress.

Dickhout JG, Sood SK, Austin RC. Dickhout JG, et al. Among authors: austin rc. Antioxid Redox Signal. 2007 Nov;9(11):1863-73. doi: 10.1089/ars.2007.1780. Antioxid Redox Signal. 2007. PMID: 17937580

10

Hyperhomocysteinemia induced by methionine supplementation does not independently cause atherosclerosis in C57BL/6J mice.

Zhou J, Werstuck GH, Lhoták S, Shi YY, Tedesco V, Trigatti B, Dickhout J, Majors AK, DiBello PM, Jacobsen DW, Austin RC. Zhou J, et al. Among authors: austin rc. FASEB J. 2008 Jul;22(7):2569-78. doi: 10.1096/fj.07-105353. Epub 2008 Mar 25. FASEB J. 2008. PMID: 18364397 Free PMC article.

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