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A new class of synthetic retinoid antibiotics effective against bacterial persisters.
Kim W, Zhu W, Hendricks GL, Van Tyne D, Steele AD, Keohane CE, Fricke N, Conery AL, Shen S, Pan W, Lee K, Rajamuthiah R, Fuchs BB, Vlahovska PM, Wuest WM, Gilmore MS, Gao H, Ausubel FM, Mylonakis E. Kim W, et al. Among authors: steele ad. Nature. 2018 Apr 5;556(7699):103-107. doi: 10.1038/nature26157. Epub 2018 Mar 28. Nature. 2018. PMID: 29590091 Free PMC article.
Discovery and Optimization of nTZDpa as an Antibiotic Effective Against Bacterial Persisters.
Kim W, Steele AD, Zhu W, Csatary EE, Fricke N, Dekarske MM, Jayamani E, Pan W, Kwon B, Sinitsa IF, Rosen JL, Conery AL, Fuchs BB, Vlahovska PM, Ausubel FM, Gao H, Wuest WM, Mylonakis E. Kim W, et al. Among authors: steele ad. ACS Infect Dis. 2018 Nov 9;4(11):1540-1545. doi: 10.1021/acsinfecdis.8b00161. Epub 2018 Aug 28. ACS Infect Dis. 2018. PMID: 30132650 Free PMC article.
A selective membrane-targeting repurposed antibiotic with activity against persistent methicillin-resistant Staphylococcus aureus.
Kim W, Zou G, Hari TPA, Wilt IK, Zhu W, Galle N, Faizi HA, Hendricks GL, Tori K, Pan W, Huang X, Steele AD, Csatary EE, Dekarske MM, Rosen JL, Ribeiro NQ, Lee K, Port J, Fuchs BB, Vlahovska PM, Wuest WM, Gao H, Ausubel FM, Mylonakis E. Kim W, et al. Among authors: steele ad. Proc Natl Acad Sci U S A. 2019 Aug 13;116(33):16529-16534. doi: 10.1073/pnas.1904700116. Epub 2019 Jul 29. Proc Natl Acad Sci U S A. 2019. PMID: 31358625 Free PMC article.
Automated home-cage behavioural phenotyping of mice.
Jhuang H, Garrote E, Mutch J, Yu X, Khilnani V, Poggio T, Steele AD, Serre T. Jhuang H, et al. Among authors: steele ad. Nat Commun. 2010 Sep 7;1:68. doi: 10.1038/ncomms1064. Nat Commun. 2010. PMID: 20842193 Free article.
UK research reform: protest now.
Curry S, Rohn J, Steele A. Curry S, et al. Nature. 2016 Nov 17;539(7629):357. doi: 10.1038/539357a. Nature. 2016. PMID: 27853194 No abstract available.
366 results