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PPARα/CB1 receptor dual ligands as a novel therapy for alcohol use disorder: Evaluation of a novel oleic acid conjugate in preclinical rat models.
Alen F, Decara J, Brunori G, You ZB, Bühler KM, López-Moreno JA, Cippitelli A, Pavon FJ, Suárez J, Gardner EL, de la Torre R, Ciccocioppo R, Serrano A, Rodríguez de Fonseca F. Alen F, et al. Among authors: brunori g. Biochem Pharmacol. 2018 Nov;157:235-243. doi: 10.1016/j.bcp.2018.09.008. Epub 2018 Sep 6. Biochem Pharmacol. 2018. PMID: 30195735
Agonist-selective NOP receptor phosphorylation correlates in vitro and in vivo and reveals differential post-activation signaling by chemically diverse agonists.
Mann A, Moulédous L, Froment C, O'Neill PR, Dasgupta P, Günther T, Brunori G, Kieffer BL, Toll L, Bruchas MR, Zaveri NT, Schulz S. Mann A, et al. Among authors: brunori g. Sci Signal. 2019 Mar 26;12(574):eaau8072. doi: 10.1126/scisignal.aau8072. Sci Signal. 2019. PMID: 30914485 Free PMC article.
NOP Receptor Antagonists Decrease Alcohol Drinking in the Dark in C57BL/6J Mice.
Brunori G, Weger M, Schoch J, Targowska-Duda K, Barnes M, Borruto AM, Rorick-Kehn LM, Zaveri NT, Pintar JE, Ciccocioppo R, Toll L, Cippitelli A. Brunori G, et al. Alcohol Clin Exp Res. 2019 Oct;43(10):2167-2178. doi: 10.1111/acer.14165. Epub 2019 Aug 21. Alcohol Clin Exp Res. 2019. PMID: 31386211 Free PMC article.
NOP receptor antagonism reduces alcohol drinking in male and female rats through mechanisms involving the central amygdala and ventral tegmental area.
Borruto AM, Fotio Y, Stopponi S, Brunori G, Petrella M, Caputi FF, Romualdi P, Candeletti S, Narendran R, Rorick-Kehn LM, Ubaldi M, Weiss F, Ciccocioppo R. Borruto AM, et al. Among authors: brunori g. Br J Pharmacol. 2020 Apr;177(7):1525-1537. doi: 10.1111/bph.14915. Epub 2020 Feb 3. Br J Pharmacol. 2020. PMID: 31713848 Free PMC article.
188 results