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KT-253, A Novel MDM2 Degrader and p53 Stabilizer, Has Superior Potency and Efficacy Than MDM2 Small Molecule Inhibitors.
Chutake YK, Mayo MF, Dumont N, Filiatrault J, Breitkopf SB, Cho P, Chen D, Dixit VS, Proctor WR, Kuhn EW, Bollinger Martinez S, McDonald AA, Qi J, Hu KN, Karnik R, Growney JD, Sharma K, Schalm SS, Gollerkeri AM, Mainolfi N, Williams JA, Weiss MM. Chutake YK, et al. Among authors: dumont n. Mol Cancer Ther. 2024 Dec 9. doi: 10.1158/1535-7163.MCT-24-0306. Online ahead of print. Mol Cancer Ther. 2024. PMID: 39648478
Adults born preterm have lower peripheral skeletal muscle area and strength.
Deprez A, El-Jalbout R, Cloutier A, Gagnon DH, Gagnon Hamelin A, Mathieu ME, Kugathasan TA, Dumont NA, Nuyt AM, Luu TM. Deprez A, et al. Among authors: dumont na. Sci Rep. 2024 Sep 13;14(1):21457. doi: 10.1038/s41598-024-72533-6. Sci Rep. 2024. PMID: 39271745 Free PMC article.
An intelligent garment for long COVID-19 real-time monitoring.
Nkengue MJ, Zeng X, Koehl L, Tao X, Dassonville F, Dumont N, Ye-Lehmann S, Akwa Y, Ye H. Nkengue MJ, et al. Among authors: dumont n. Comput Biol Med. 2024 Oct;181:109067. doi: 10.1016/j.compbiomed.2024.109067. Epub 2024 Aug 24. Comput Biol Med. 2024. PMID: 39182371 Free article.
Bi-allelic variants in MYH3 cause recessively-inherited arthrogryposis.
Morali B, Miranda V, Raelson J, Grimard G, Glavas P, Audibert F, Dumont NA, Barone J, Bamshad M, Lemyre E, Campeau PM. Morali B, et al. Among authors: dumont na. Clin Genet. 2024 Oct;106(4):483-487. doi: 10.1111/cge.14570. Epub 2024 Jun 10. Clin Genet. 2024. PMID: 38856159
Identification of Small Molecule Inhibitors of PPM1D Using a Novel Drug Discovery Platform.
Jiang W, Shaw S, Rush J, Dumont N, Kim J, Singh R, Skepner A, Khodier C, Raffier C, Yan N, Schluter C, Yu X, Szuchnicki M, Sathappa M, Kahn J, Sperling AS, McKinney DC, Gould AE, Garvie CW, Miller PG. Jiang W, et al. Among authors: dumont n. bioRxiv [Preprint]. 2024 May 21:2024.05.20.595001. doi: 10.1101/2024.05.20.595001. bioRxiv. 2024. PMID: 38826457 Free PMC article. Preprint.
Disturbance of the human gut microbiota in patients with Myotonic Dystrophy type 1.
Mahdavi M, Prévost K, Balthazar P, Hus IF, Duchesne É, Dumont N, Gagné-Ouellet V, Gagnon C, Laforest-Lapointe I, Massé E. Mahdavi M, et al. Among authors: dumont n. Comput Struct Biotechnol J. 2024 May 9;23:2097-2108. doi: 10.1016/j.csbj.2024.05.009. eCollection 2024 Dec. Comput Struct Biotechnol J. 2024. PMID: 38803516 Free PMC article.
Apelin stimulation of the vascular skeletal muscle stem cell niche enhances endogenous repair in dystrophic mice.
Le Moal E, Liu Y, Collerette-Tremblay J, Dumontier S, Fabre P, Molina T, Dort J, Orfi Z, Denault N, Boutin J, Michaud J, Giguère H, Desroches A, Trân K, Ellezam B, Vézina F, Bedard S, Raynaud C, Balg F, Sarret P, Boudreault PL, Scott MS, Denault JB, Marsault E, Feige JN, Auger-Messier M, Dumont NA, Bentzinger CF. Le Moal E, et al. Among authors: dumont na. Sci Transl Med. 2024 Mar 20;16(739):eabn8529. doi: 10.1126/scitranslmed.abn8529. Epub 2024 Mar 20. Sci Transl Med. 2024. PMID: 38507466
181 results