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Page 1
Induction of hemangiosarcoma in mice after chronic treatment with S1P-modulator siponimod and its lack of relevance to rat and human.
Pognan F, Mahl JA, Papoutsi M, Ledieu D, Raccuglia M, Theil D, Voytek SB, Devine PJ, Kubek-Luck K, Claudio N, Cordier A, Heier A, Kolly C, Hartmann A, Chibout SD, Bouchard P, Trendelenburg C. Pognan F, et al. Among authors: cordier a. Arch Toxicol. 2018 May;92(5):1877-1891. doi: 10.1007/s00204-018-2189-9. Epub 2018 Mar 19. Arch Toxicol. 2018. PMID: 29556671 Free PMC article.
Investigative safety science as a competitive advantage for Pharma.
Moggs J, Moulin P, Pognan F, Brees D, Leonard M, Busch S, Cordier A, Heard DJ, Kammüller M, Merz M, Bouchard P, Chibout SD. Moggs J, et al. Among authors: cordier a. Expert Opin Drug Metab Toxicol. 2012 Sep;8(9):1071-82. doi: 10.1517/17425255.2012.693914. Epub 2012 Jul 7. Expert Opin Drug Metab Toxicol. 2012. PMID: 22769724 Review.
Vitamin D3 24-hydroxylase mRNA expression in the skin of calcipotriol-treated psoriatic patients correlates with clinical efficacy.
Chibout SD, de Brugerolle de Fraissinette A, Hartmann N, Picarles V, Grenet O, Cordier A, Molloy S, Medina J. Chibout SD, et al. Among authors: cordier a. Arch Dermatol Res. 2003 Nov;295(6):269-71. doi: 10.1007/s00403-003-0428-1. Epub 2003 Sep 23. Arch Dermatol Res. 2003. PMID: 14504887 Clinical Trial. No abstract available.
Predictivity of an in vitro model for acute and chronic skin irritation (SkinEthic) applied to the testing of topical vehicles.
de Brugerolle de Fraissinette, Picarles V, Chibout S, Kolopp M, Medina J, Burtin P, Ebelin ME, Osborne S, Mayer FK, Spake A, Rosdy M, De Wever B, Ettlin RA, Cordier A. de Brugerolle de Fraissinette, et al. Among authors: cordier a. Cell Biol Toxicol. 1999 Apr;15(2):121-35. doi: 10.1023/a:1007577515215. Cell Biol Toxicol. 1999. PMID: 10408359
Cyclosporine A-induced oxidative stress in rat hepatocytes.
Wolf A, Trendelenburg CF, Diez-Fernandez C, Prieto P, Houy S, Trommer WE, Cordier A. Wolf A, et al. Among authors: cordier a. J Pharmacol Exp Ther. 1997 Mar;280(3):1328-34. J Pharmacol Exp Ther. 1997. PMID: 9067320
A panel of urinary biomarkers to monitor reversibility of renal injury and a serum marker with improved potential to assess renal function.
Ozer JS, Dieterle F, Troth S, Perentes E, Cordier A, Verdes P, Staedtler F, Mahl A, Grenet O, Roth DR, Wahl D, Legay F, Holder D, Erdos Z, Vlasakova K, Jin H, Yu Y, Muniappa N, Forest T, Clouse HK, Reynolds S, Bailey WJ, Thudium DT, Topper MJ, Skopek TR, Sina JF, Glaab WE, Vonderscher J, Maurer G, Chibout SD, Sistare FD, Gerhold DL. Ozer JS, et al. Among authors: cordier a. Nat Biotechnol. 2010 May;28(5):486-94. doi: 10.1038/nbt.1627. Nat Biotechnol. 2010. PMID: 20458319
235 results