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Identification and Characterization of Novel Receptor-Interacting Serine/Threonine-Protein Kinase 2 Inhibitors Using Structural Similarity Analysis.
Salla M, Aguayo-Ortiz R, Danmaliki GI, Zare A, Said A, Moore J, Pandya V, Manaloor R, Fong S, Blankstein AR, Gibson SB, Garcia LR, Meier P, Bhullar KS, Hubbard BP, Fiteh Y, Vliagoftis H, Goping IS, Brocks D, Hwang P, Velázquez-Martínez CA, Baksh S. Salla M, et al. Among authors: meier p. J Pharmacol Exp Ther. 2018 May;365(2):354-367. doi: 10.1124/jpet.117.247163. Epub 2018 Mar 19. J Pharmacol Exp Ther. 2018. PMID: 29555876
Impact of protein and small molecule interactions on kinase conformations.
Kugler V, Schwaighofer S, Feichtner A, Enzler F, Fleischmann J, Strich S, Schwarz S, Wilson R, Tschaikner P, Troppmair J, Sexl V, Meier P, Kaserer T, Stefan E. Kugler V, et al. Among authors: meier p. Elife. 2024 Aug 1;13:RP94755. doi: 10.7554/eLife.94755. Elife. 2024. PMID: 39088265 Free PMC article.
IAPs: guardians of RIPK1.
Darding M, Meier P. Darding M, et al. Among authors: meier p. Cell Death Differ. 2012 Jan;19(1):58-66. doi: 10.1038/cdd.2011.163. Epub 2011 Nov 18. Cell Death Differ. 2012. PMID: 22095281 Free PMC article. Review.
Time-lapse imaging of necrosis.
Wållberg F, Tenev T, Meier P. Wållberg F, et al. Among authors: meier p. Methods Mol Biol. 2013;1004:17-29. doi: 10.1007/978-1-62703-383-1_2. Methods Mol Biol. 2013. PMID: 23733566
Ubiquitylation of MLKL at lysine 219 positively regulates necroptosis-induced tissue injury and pathogen clearance.
Garcia LR, Tenev T, Newman R, Haich RO, Liccardi G, John SW, Annibaldi A, Yu L, Pardo M, Young SN, Fitzgibbon C, Fernando W, Guppy N, Kim H, Liang LY, Lucet IS, Kueh A, Roxanis I, Gazinska P, Sims M, Smyth T, Ward G, Bertin J, Beal AM, Geddes B, Choudhary JS, Murphy JM, Aurelia Ball K, Upton JW, Meier P. Garcia LR, et al. Among authors: meier p. Nat Commun. 2021 Jun 7;12(1):3364. doi: 10.1038/s41467-021-23474-5. Nat Commun. 2021. PMID: 34099649 Free PMC article.
The unconventional myosin CRINKLED and its mammalian orthologue MYO7A regulate caspases in their signalling roles.
Orme MH, Liccardi G, Moderau N, Feltham R, Wicky-John S, Tenev T, Aram L, Wilson R, Bianchi K, Morris O, Monteiro Domingues C, Robertson D, Tare M, Wepf A, Williams D, Bergmann A, Gstaiger M, Arama E, Ribeiro PS, Meier P. Orme MH, et al. Among authors: meier p. Nat Commun. 2016 Mar 10;7:10972. doi: 10.1038/ncomms10972. Nat Commun. 2016. PMID: 26960254 Free PMC article.
MK2 Phosphorylates RIPK1 to Prevent TNF-Induced Cell Death.
Jaco I, Annibaldi A, Lalaoui N, Wilson R, Tenev T, Laurien L, Kim C, Jamal K, Wicky John S, Liccardi G, Chau D, Murphy JM, Brumatti G, Feltham R, Pasparakis M, Silke J, Meier P. Jaco I, et al. Among authors: meier p. Mol Cell. 2017 Jun 1;66(5):698-710.e5. doi: 10.1016/j.molcel.2017.05.003. Epub 2017 May 11. Mol Cell. 2017. PMID: 28506461 Free PMC article.
1,395 results