Kinman LM - Search Results

1

Long-Acting Profile of 4 Drugs in 1 Anti-HIV Nanosuspension in Nonhuman Primates for 5 Weeks After a Single Subcutaneous Injection.

McConnachie LA, Kinman LM, Koehn J, Kraft JC, Lane S, Lee W, Collier AC, Ho RJY. McConnachie LA, et al. Among authors: kinman lm. J Pharm Sci. 2018 Jul;107(7):1787-1790. doi: 10.1016/j.xphs.2018.03.005. Epub 2018 Mar 13. J Pharm Sci. 2018. PMID: 29548975 Free PMC article.

2

Long-acting combination anti-HIV drug suspension enhances and sustains higher drug levels in lymph node cells than in blood cells and plasma.

Kraft JC, McConnachie LA, Koehn J, Kinman L, Collins C, Shen DD, Collier AC, Ho RJ. Kraft JC, et al. AIDS. 2017 Mar 27;31(6):765-770. doi: 10.1097/QAD.0000000000001405. AIDS. 2017. PMID: 28099191 Free PMC article.

3

Mechanism-based pharmacokinetic (MBPK) models describe the complex plasma kinetics of three antiretrovirals delivered by a long-acting anti-HIV drug combination nanoparticle formulation.

Kraft JC, McConnachie LA, Koehn J, Kinman L, Sun J, Collier AC, Collins C, Shen DD, Ho RJY. Kraft JC, et al. J Control Release. 2018 Apr 10;275:229-241. doi: 10.1016/j.jconrel.2018.02.003. Epub 2018 Feb 10. J Control Release. 2018. PMID: 29432823 Free PMC article.

4

Integration of Computational and Experimental Approaches to Elucidate Mechanisms of First-Pass Lymphatic Drug Sequestration and Long-Acting Pharmacokinetics of the Injectable Triple-HIV Drug Combination TLC-ART 101.

Perazzolo S, Shireman LM, McConnachie LA, Koehn J, Kinman L, Lee W, Lane S, Collier AC, Shen DD, Ho RJY. Perazzolo S, et al. Among authors: kinman l. J Pharm Sci. 2020 May;109(5):1789-1801. doi: 10.1016/j.xphs.2020.01.016. Epub 2020 Jan 29. J Pharm Sci. 2020. PMID: 32006525 Free PMC article.

5

Optimization of lipid-indinavir complexes for localization in lymphoid tissues of HIV-infected macaques.

Kinman L, Bui T, Larsen K, Tsai CC, Anderson D, Morton WR, Hu SL, Ho RJ. Kinman L, et al. J Acquir Immune Defic Syndr. 2006 Jun;42(2):155-61. doi: 10.1097/01.qai.0000214822.33905.87. J Acquir Immune Defic Syndr. 2006. PMID: 16760797

6

Lipid-drug association enhanced HIV-1 protease inhibitor indinavir localization in lymphoid tissues and viral load reduction: a proof of concept study in HIV-2287-infected macaques.

Kinman L, Brodie SJ, Tsai CC, Bui T, Larsen K, Schmidt A, Anderson D, Morton WR, Hu SL, Ho RJ. Kinman L, et al. J Acquir Immune Defic Syndr. 2003 Dec 1;34(4):387-97. doi: 10.1097/00126334-200312010-00005. J Acquir Immune Defic Syndr. 2003. PMID: 14615656

7

HIV in central nervous system and behavioral development: an HIV-2287 macaque model of AIDS.

Kinman LM, Worlein JM, Leigh J, Bielefeldt-Ohmann H, Anderson DM, Hu SL, Morton WR, Anderson BD, Ho RJ. Kinman LM, et al. AIDS. 2004 Jul 2;18(10):1363-70. doi: 10.1097/01.aids.0000131307.62828.a1. AIDS. 2004. PMID: 15199312

8

Inhibition of P-glycoprotein activity at the primate blood-brain barrier increases the distribution of nelfinavir into the brain but not into the cerebrospinal fluid.

Kaddoumi A, Choi SU, Kinman L, Whittington D, Tsai CC, Ho RJ, Anderson BD, Unadkat JD. Kaddoumi A, et al. Drug Metab Dispos. 2007 Sep;35(9):1459-62. doi: 10.1124/dmd.107.016220. Epub 2007 Jun 25. Drug Metab Dispos. 2007. PMID: 17591677

9

Cognitive and motor deficits associated with HIV-2(287) infection in infant pigtailed macaques: a nonhuman primate model of pediatric neuro-AIDS.

Worlein JM, Leigh J, Larsen K, Kinman L, Schmidt A, Ochs H, Ho RJ. Worlein JM, et al. J Neurovirol. 2005 Feb;11(1):34-45. doi: 10.1080/13550280590901732. J Neurovirol. 2005. PMID: 15804957

10

Characterization of a maternal-fetal HIV transmission model using pregnant macaques infected with HIV-2(287).

Ho RJ, Larsen K, Kinman L, Sherbert C, Wang XY, Finn E, Nosbisch C, Schmidt A, Anderson D, Hu SL, Agy M, Ochs H, Morton WR, Unadkat JD. Ho RJ, et al. J Med Primatol. 2001 Jun;30(3):131-40. doi: 10.1111/j.1600-0684.2001.tb00001.x. J Med Primatol. 2001. PMID: 11515668

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