Gonzalez N - Search Results

1

Relevance of small GTPase Rac1 pathway in drug and radio-resistance mechanisms: Opportunities in cancer therapeutics.

Cardama GA, Alonso DF, Gonzalez N, Maggio J, Gomez DE, Rolfo C, Menna PL. Cardama GA, et al. Among authors: gonzalez n. Crit Rev Oncol Hematol. 2018 Apr;124:29-36. doi: 10.1016/j.critrevonc.2018.01.012. Epub 2018 Feb 4. Crit Rev Oncol Hematol. 2018. PMID: 29548483 Review.

2

Pharmacological inhibition of Rac1-PAK1 axis restores tamoxifen sensitivity in human resistant breast cancer cells.

Gonzalez N, Cardama GA, Comin MJ, Segatori VI, Pifano M, Alonso DF, Gomez DE, Menna PL. Gonzalez N, et al. Cell Signal. 2017 Jan;30:154-161. doi: 10.1016/j.cellsig.2016.12.002. Epub 2016 Dec 7. Cell Signal. 2017. PMID: 27939839

3

Rho GTPases as therapeutic targets in cancer (Review).

Cardama GA, Gonzalez N, Maggio J, Menna PL, Gomez DE. Cardama GA, et al. Among authors: gonzalez n. Int J Oncol. 2017 Oct;51(4):1025-1034. doi: 10.3892/ijo.2017.4093. Epub 2017 Aug 9. Int J Oncol. 2017. PMID: 28848995 Free PMC article. Review.

4

[Rho GTPases as molecular targets in cancer. Strategies and therapeutic opportunities].

Maggio J, González N, Cardama GA, Gomez DE. Maggio J, et al. Among authors: gonzalez n. Medicina (B Aires). 2017;77(6):497-504. Medicina (B Aires). 2017. PMID: 29223942 Free article. Review. Spanish.

5

Preclinical development of novel Rac1-GEF signaling inhibitors using a rational design approach in highly aggressive breast cancer cell lines.

Cardama GA, Comin MJ, Hornos L, Gonzalez N, Defelipe L, Turjanski AG, Alonso DF, Gomez DE, Menna PL. Cardama GA, et al. Among authors: gonzalez n. Anticancer Agents Med Chem. 2014;14(6):840-51. doi: 10.2174/18715206113136660334. Anticancer Agents Med Chem. 2014. PMID: 24066799 Free PMC article.

6

Proapoptotic and antiinvasive activity of Rac1 small molecule inhibitors on malignant glioma cells.

Cardama GA, Gonzalez N, Ciarlantini M, Gandolfi Donadío L, Comin MJ, Alonso DF, Menna PL, Gomez DE. Cardama GA, et al. Among authors: gonzalez n. Onco Targets Ther. 2014 Oct 30;7:2021-33. doi: 10.2147/OTT.S67998. eCollection 2014. Onco Targets Ther. 2014. PMID: 25378937 Free PMC article.

7

Computational and in vitro Pharmacodynamics Characterization of 1A-116 Rac1 Inhibitor: Relevance of Trp56 in Its Biological Activity.

González N, Cardama GA, Chinestrad P, Robles-Valero J, Rodríguez-Fdez S, Lorenzo-Martín LF, Bustelo XR, Lorenzano Menna P, Gomez DE. González N, et al. Front Cell Dev Biol. 2020 Apr 15;8:240. doi: 10.3389/fcell.2020.00240. eCollection 2020. Front Cell Dev Biol. 2020. PMID: 32351958 Free PMC article.

8

Pharmacological Rac1 inhibitors with selective apoptotic activity in human acute leukemic cell lines.

Cabrera M, Echeverria E, Lenicov FR, Cardama G, Gonzalez N, Davio C, Fernández N, Menna PL. Cabrera M, et al. Among authors: gonzalez n. Oncotarget. 2017 Oct 4;8(58):98509-98523. doi: 10.18632/oncotarget.21533. eCollection 2017 Nov 17. Oncotarget. 2017. PMID: 29228706 Free PMC article.

9

Preclinical Efficacy and Toxicology Evaluation of RAC1 Inhibitor 1A-116 in Human Glioblastoma Models.

Cardama GA, Maggio J, Valdez Capuccino L, Gonzalez N, Matiller V, Ortega HH, Perez GR, Demarco IA, Spitzer E, Gomez DE, Lorenzano Menna P, Alonso DF. Cardama GA, et al. Among authors: gonzalez n. Cancers (Basel). 2022 Sep 30;14(19):4810. doi: 10.3390/cancers14194810. Cancers (Basel). 2022. PMID: 36230732 Free PMC article.

10

Peptide Agonists of Vasopressin V2 Receptor Reduce Expression of Neuroendocrine Markers and Tumor Growth in Human Lung and Prostate Tumor Cells.

Pifano M, Garona J, Capobianco CS, Gonzalez N, Alonso DF, Ripoll GV. Pifano M, et al. Among authors: gonzalez n. Front Oncol. 2017 Jan 30;7:11. doi: 10.3389/fonc.2017.00011. eCollection 2017. Front Oncol. 2017. PMID: 28194370 Free PMC article.

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