Jantos K - Search Results

1

Mitigating the Metabolic Liability of Carbonyl Reduction: Novel Calpain Inhibitors with P1' Extension.

Kling A, Jantos K, Mack H, Hornberger W, Backfisch G, Lao Y, Nijsen M, Rendenbach-Mueller B, Moeller A. Kling A, et al. Among authors: jantos k. ACS Med Chem Lett. 2018 Feb 4;9(3):221-226. doi: 10.1021/acsmedchemlett.7b00494. eCollection 2018 Mar 8. ACS Med Chem Lett. 2018. PMID: 29541364 Free PMC article.

2

Discovery of Novel and Highly Selective Inhibitors of Calpain for the Treatment of Alzheimer's Disease: 2-(3-Phenyl-1H-pyrazol-1-yl)-nicotinamides.

Kling A, Jantos K, Mack H, Hornberger W, Drescher K, Nimmrich V, Relo A, Wicke K, Hutchins CW, Lao Y, Marsh K, Moeller A. Kling A, et al. Among authors: jantos k. J Med Chem. 2017 Aug 24;60(16):7123-7138. doi: 10.1021/acs.jmedchem.7b00731. Epub 2017 Aug 15. J Med Chem. 2017. PMID: 28759231

3

Discovery of ABT-957: 1-Benzyl-5-oxopyrrolidine-2-carboxamides as selective calpain inhibitors with enhanced metabolic stability.

Jantos K, Kling A, Mack H, Hornberger W, Moeller A, Nimmrich V, Lao Y, Nijsen M. Jantos K, et al. Bioorg Med Chem Lett. 2019 Aug 1;29(15):1968-1973. doi: 10.1016/j.bmcl.2019.05.034. Epub 2019 May 18. Bioorg Med Chem Lett. 2019. PMID: 31133534

4

Exploring the differential recognition of DNA G-quadruplex targets by small molecules using dynamic combinatorial chemistry.

Bugaut A, Jantos K, Wietor JL, Rodriguez R, Sanders JK, Balasubramanian S. Bugaut A, et al. Among authors: jantos k. Angew Chem Int Ed Engl. 2008;47(14):2677-80. doi: 10.1002/anie.200705589. Angew Chem Int Ed Engl. 2008. PMID: 18300215 Free PMC article. No abstract available.

5

Oxazole-based peptide macrocycles: a new class of G-quadruplex binding ligands.

Jantos K, Rodriguez R, Ladame S, Shirude PS, Balasubramanian S. Jantos K, et al. J Am Chem Soc. 2006 Oct 25;128(42):13662-3. doi: 10.1021/ja064713e. J Am Chem Soc. 2006. PMID: 17044674 Free PMC article.

6

One-pot homolytic aromatic substitutions/HWE olefinations under microwave conditions for the formation of a small oxindole library.

Teichert A, Jantos K, Harms K, Studer A. Teichert A, et al. Among authors: jantos k. Org Lett. 2004 Sep 30;6(20):3477-80. doi: 10.1021/ol048759t. Org Lett. 2004. PMID: 15387527

7

Intermolecular radical addition and addition/cyclization reactions of alkoxyamines onto nonactivated alkenes.

Wetter C, Jantos K, Woithe K, Studer A. Wetter C, et al. Among authors: jantos k. Org Lett. 2003 Aug 7;5(16):2899-902. doi: 10.1021/ol034994k. Org Lett. 2003. PMID: 12889903

8

Synthesis of a deca-lithium cage containing an [(RN)2As(mu-NR)As(NR)2]4- tetraanion; a homologue of group 15 trianions of the type [E(NR)3]3-.

Bond AD, García F, Jantos K, Lawson GT, McPartlin M, Wright DS. Bond AD, et al. Among authors: jantos k. Chem Commun (Camb). 2002 Jun 21;(12):1276-7. doi: 10.1039/b202858a. Chem Commun (Camb). 2002. PMID: 12109113

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