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Efficacy and safety of ridinilazole compared with vancomycin for the treatment of Clostridium difficile infection: a phase 2, randomised, double-blind, active-controlled, non-inferiority study.
Vickers RJ, Tillotson GS, Nathan R, Hazan S, Pullman J, Lucasti C, Deck K, Yacyshyn B, Maliakkal B, Pesant Y, Tejura B, Roblin D, Gerding DN, Wilcox MH; CoDIFy study group. Vickers RJ, et al. Among authors: yacyshyn b. Lancet Infect Dis. 2017 Jul;17(7):735-744. doi: 10.1016/S1473-3099(17)30235-9. Epub 2017 Apr 28. Lancet Infect Dis. 2017. PMID: 28461207 Free PMC article. Clinical Trial.
Human Clostridium difficile infection: inhibition of NHE3 and microbiota profile.
Engevik MA, Engevik KA, Yacyshyn MB, Wang J, Hassett DJ, Darien B, Yacyshyn BR, Worrell RT. Engevik MA, et al. Among authors: yacyshyn br, yacyshyn mb. Am J Physiol Gastrointest Liver Physiol. 2015 Mar 15;308(6):G497-509. doi: 10.1152/ajpgi.00090.2014. Epub 2014 Dec 31. Am J Physiol Gastrointest Liver Physiol. 2015. PMID: 25552580 Free PMC article.
Human Clostridium difficile infection: altered mucus production and composition.
Engevik MA, Yacyshyn MB, Engevik KA, Wang J, Darien B, Hassett DJ, Yacyshyn BR, Worrell RT. Engevik MA, et al. Among authors: yacyshyn br, yacyshyn mb. Am J Physiol Gastrointest Liver Physiol. 2015 Mar 15;308(6):G510-24. doi: 10.1152/ajpgi.00091.2014. Epub 2014 Dec 31. Am J Physiol Gastrointest Liver Physiol. 2015. PMID: 25552581 Free PMC article.
Clostridium difficile toxins A and B decrease intestinal SLC26A3 protein expression.
Coffing H, Priyamvada S, Anbazhagan AN, Salibay C, Engevik M, Versalovic J, Yacyshyn MB, Yacyshyn B, Tyagi S, Saksena S, Gill RK, Alrefai WA, Dudeja PK. Coffing H, et al. Among authors: yacyshyn b, yacyshyn mb. Am J Physiol Gastrointest Liver Physiol. 2018 Jul 1;315(1):G43-G52. doi: 10.1152/ajpgi.00307.2017. Epub 2018 Mar 29. Am J Physiol Gastrointest Liver Physiol. 2018. PMID: 29597352 Free PMC article.
71 results