O'Prey J - Search Results

1

Autophagy Inhibition Mediates Apoptosis Sensitization in Cancer Therapy by Relieving FOXO3a Turnover.

Fitzwalter BE, Towers CG, Sullivan KD, Andrysik Z, Hoh M, Ludwig M, O'Prey J, Ryan KM, Espinosa JM, Morgan MJ, Thorburn A. Fitzwalter BE, et al. Among authors: o prey j. Dev Cell. 2018 Mar 12;44(5):555-565.e3. doi: 10.1016/j.devcel.2018.02.014. Dev Cell. 2018. PMID: 29533771 Free PMC article.

2

Extracellular adenosine sensing-a metabolic cell death priming mechanism downstream of p53.

Long JS, Crighton D, O'Prey J, Mackay G, Zheng L, Palmer TM, Gottlieb E, Ryan KM. Long JS, et al. Mol Cell. 2013 May 9;50(3):394-406. doi: 10.1016/j.molcel.2013.03.016. Epub 2013 Apr 18. Mol Cell. 2013. PMID: 23603120 Free article.

3

DRAM, a p53-induced modulator of autophagy, is critical for apoptosis.

Crighton D, Wilkinson S, O'Prey J, Syed N, Smith P, Harrison PR, Gasco M, Garrone O, Crook T, Ryan KM. Crighton D, et al. Cell. 2006 Jul 14;126(1):121-34. doi: 10.1016/j.cell.2006.05.034. Cell. 2006. PMID: 16839881 Free article.

4

Tumor antigen LRRC15 impedes adenoviral infection: implications for virus-based cancer therapy.

O'Prey J, Wilkinson S, Ryan KM. O'Prey J, et al. J Virol. 2008 Jun;82(12):5933-9. doi: 10.1128/JVI.02273-07. Epub 2008 Apr 2. J Virol. 2008. PMID: 18385238 Free PMC article.

5

Oncogene-induced sensitization to chemotherapy-induced death requires induction as well as deregulation of E2F1.

Helgason GV, O'Prey J, Ryan KM. Helgason GV, et al. Cancer Res. 2010 May 15;70(10):4074-80. doi: 10.1158/0008-5472.CAN-09-2876. Epub 2010 May 11. Cancer Res. 2010. PMID: 20460519 Free PMC article.

6

Does androgen-ablation therapy (AAT) associated autophagy have a pro-survival effect in LNCaP human prostate cancer cells?

Bennett HL, Stockley J, Fleming JT, Mandal R, O'Prey J, Ryan KM, Robson CN, Leung HY. Bennett HL, et al. BJU Int. 2013 Apr;111(4):672-82. doi: 10.1111/j.1464-410X.2012.11409.x. Epub 2012 Aug 16. BJU Int. 2013. PMID: 22897391

7

p73 regulates DRAM-independent autophagy that does not contribute to programmed cell death.

Crighton D, O'Prey J, Bell HS, Ryan KM. Crighton D, et al. Cell Death Differ. 2007 Jun;14(6):1071-9. doi: 10.1038/sj.cdd.4402108. Epub 2007 Feb 16. Cell Death Differ. 2007. PMID: 17304243

8

Phosphorylation of Puma modulates its apoptotic function by regulating protein stability.

Fricker M, O'Prey J, Tolkovsky AM, Ryan KM. Fricker M, et al. Cell Death Dis. 2010 Jul 29;1(7):e59. doi: 10.1038/cddis.2010.38. Cell Death Dis. 2010. PMID: 21364664 Free PMC article.

9

mTORC1-independent autophagy regulates receptor tyrosine kinase phosphorylation in colorectal cancer cells via an mTORC2-mediated mechanism.

Lampada A, O'Prey J, Szabadkai G, Ryan KM, Hochhauser D, Salomoni P. Lampada A, et al. Cell Death Differ. 2017 Jun;24(6):1045-1062. doi: 10.1038/cdd.2017.41. Epub 2017 May 5. Cell Death Differ. 2017. PMID: 28475179 Free PMC article.

10

DRAM-4 and DRAM-5 are compensatory regulators of autophagy and cell survival in nutrient-deprived conditions.

Barthet VJA, Mrschtik M, Kania E, McEwan DG, Croft D, O'Prey J, Long JS, Ryan KM. Barthet VJA, et al. Among authors: o prey j. FEBS J. 2022 Jul;289(13):3752-3769. doi: 10.1111/febs.16365. Epub 2022 Feb 4. FEBS J. 2022. PMID: 35060334 Free PMC article.

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