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Mitochondrial fission protein Drp1 inhibition promotes cardiac mesodermal differentiation of human pluripotent stem cells.
Hoque A, Sivakumaran P, Bond ST, Ling NXY, Kong AM, Scott JW, Bandara N, Hernández D, Liu GS, Wong RCB, Ryan MT, Hausenloy DJ, Kemp BE, Oakhill JS, Drew BG, Pébay A, Lim SY. Hoque A, et al. Among authors: ryan mt. Cell Death Discov. 2018 Mar 5;4:39. doi: 10.1038/s41420-018-0042-9. eCollection 2018 Dec. Cell Death Discov. 2018. PMID: 29531836 Free PMC article.
Deficiency in Apoptosis-Inducing Factor Recapitulates Chronic Kidney Disease via Aberrant Mitochondrial Homeostasis.
Coughlan MT, Higgins GC, Nguyen TV, Penfold SA, Thallas-Bonke V, Tan SM, Ramm G, Van Bergen NJ, Henstridge DC, Sourris KC, Harcourt BE, Trounce IA, Robb PM, Laskowski A, McGee SL, Genders AJ, Walder K, Drew BG, Gregorevic P, Qian H, Thomas MC, Jerums G, Macisaac RJ, Skene A, Power DA, Ekinci EI, Wijeyeratne XW, Gallo LA, Herman-Edelstein M, Ryan MT, Cooper ME, Thorburn DR, Forbes JM. Coughlan MT, et al. Among authors: ryan mt. Diabetes. 2016 Apr;65(4):1085-98. doi: 10.2337/db15-0864. Epub 2016 Jan 28. Diabetes. 2016. PMID: 26822084
Loss of BIM increases mitochondrial oxygen consumption and lipid oxidation, reduces adiposity and improves insulin sensitivity in mice.
Wali JA, Galic S, Tan CY, Gurzov EN, Frazier AE, Connor T, Ge J, Pappas EG, Stroud D, Varanasi LC, Selck C, Ryan MT, Thorburn DR, Kemp BE, Krishnamurthy B, Kay TW, McGee SL, Thomas HE. Wali JA, et al. Among authors: ryan mt. Cell Death Differ. 2018 Jan;25(1):217-225. doi: 10.1038/cdd.2017.168. Epub 2017 Oct 20. Cell Death Differ. 2018. PMID: 29053141 Free PMC article.
Recent advances into the understanding of mitochondrial fission.
Elgass K, Pakay J, Ryan MT, Palmer CS. Elgass K, et al. Among authors: ryan mt. Biochim Biophys Acta. 2013 Jan;1833(1):150-61. doi: 10.1016/j.bbamcr.2012.05.002. Epub 2012 May 10. Biochim Biophys Acta. 2013. PMID: 22580041 Free article. Review.
233 results