Nagy GN - Search Results

1

Structural model of human dUTPase in complex with a novel proteinaceous inhibitor.

Nyíri K, Mertens HDT, Tihanyi B, Nagy GN, Kőhegyi B, Matejka J, Harris MJ, Szabó JE, Papp-Kádár V, Németh-Pongrácz V, Ozohanics O, Vékey K, Svergun DI, Borysik AJ, Vértessy BG. Nyíri K, et al. Among authors: nagy gn. Sci Rep. 2018 Mar 12;8(1):4326. doi: 10.1038/s41598-018-22145-8. Sci Rep. 2018. PMID: 29531348 Free PMC article.

2

Direct contacts between conserved motifs of different subunits provide major contribution to active site organization in human and mycobacterial dUTPases.

Takács E, Nagy G, Leveles I, Harmat V, Lopata A, Tóth J, Vértessy BG. Takács E, et al. FEBS Lett. 2010 Jul 16;584(14):3047-54. doi: 10.1016/j.febslet.2010.05.018. Epub 2010 May 21. FEBS Lett. 2010. PMID: 20493855 Free PMC article.

3

Evolutionary and mechanistic insights into substrate and product accommodation of CTP:phosphocholine cytidylyltransferase from Plasmodium falciparum.

Nagy GN, Marton L, Krámos B, Oláh J, Révész Á, Vékey K, Delsuc F, Hunyadi-Gulyás É, Medzihradszky KF, Lavigne M, Vial H, Cerdan R, Vértessy BG. Nagy GN, et al. FEBS J. 2013 Jul;280(13):3132-48. doi: 10.1111/febs.12282. Epub 2013 May 24. FEBS J. 2013. PMID: 23578277 Free article.

4

Preventive DNA repair by sanitizing the cellular (deoxy)nucleoside triphosphate pool.

Nagy GN, Leveles I, Vértessy BG. Nagy GN, et al. FEBS J. 2014 Sep;281(18):4207-23. doi: 10.1111/febs.12941. Epub 2014 Aug 18. FEBS J. 2014. PMID: 25052017 Free article. Review.

5

NLS copy-number variation governs efficiency of nuclear import--case study on dUTPases.

Róna G, Pálinkás HL, Borsos M, Horváth A, Scheer I, Benedek A, Nagy GN, Zagyva I, Vértessy BG. Róna G, et al. Among authors: nagy gn. FEBS J. 2014 Dec;281(24):5463-78. doi: 10.1111/febs.13086. Epub 2014 Oct 25. FEBS J. 2014. PMID: 25283549 Free article.

6

Composite aromatic boxes for enzymatic transformations of quaternary ammonium substrates.

Nagy GN, Marton L, Contet A, Ozohanics O, Ardelean LM, Révész A, Vékey K, Irimie FD, Vial H, Cerdan R, Vértessy BG. Nagy GN, et al. Angew Chem Int Ed Engl. 2014 Dec 1;53(49):13471-6. doi: 10.1002/anie.201408246. Epub 2014 Oct 5. Angew Chem Int Ed Engl. 2014. PMID: 25283789

7

Molecular Mechanism for the Thermo-Sensitive Phenotype of CHO-MT58 Cell Line Harbouring a Mutant CTP:Phosphocholine Cytidylyltransferase.

Marton L, Nagy GN, Ozohanics O, Lábas A, Krámos B, Oláh J, Vékey K, Vértessy BG. Marton L, et al. Among authors: nagy gn. PLoS One. 2015 Jun 17;10(6):e0129632. doi: 10.1371/journal.pone.0129632. eCollection 2015. PLoS One. 2015. PMID: 26083347 Free PMC article.

8

Corrigendum: Composite Aromatic Boxes for Enzymatic Transformations of Quaternary Ammonium Substrates.

Nagy GN, Marton L, Contet A, Ozohanics O, Ardelean LM, Révész Á, Vékey K, Irimie FD, Vial H, Cerdan R, Vértessy BG. Nagy GN, et al. Angew Chem Int Ed Engl. 2015 Jul 27;54(31):8866. doi: 10.1002/anie.201505314. Angew Chem Int Ed Engl. 2015. PMID: 26199125 No abstract available.

9

Potential steps in the evolution of a fused trimeric all-β dUTPase involve a catalytically competent fused dimeric intermediate.

Benedek A, Horváth A, Hirmondó R, Ozohanics O, Békési A, Módos K, Révész Á, Vékey K, Nagy GN, Vértessy BG. Benedek A, et al. Among authors: nagy gn. FEBS J. 2016 Sep;283(18):3268-86. doi: 10.1111/febs.13800. Epub 2016 Jul 27. FEBS J. 2016. PMID: 27380921 Free article.

10

Structural Characterization of Arginine Fingers: Identification of an Arginine Finger for the Pyrophosphatase dUTPases.

Nagy GN, Suardíaz R, Lopata A, Ozohanics O, Vékey K, Brooks BR, Leveles I, Tóth J, Vértessy BG, Rosta E. Nagy GN, et al. J Am Chem Soc. 2016 Nov 16;138(45):15035-15045. doi: 10.1021/jacs.6b09012. Epub 2016 Nov 4. J Am Chem Soc. 2016. PMID: 27740761 Free article.

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