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Imaging of tumor-associated macrophage dynamics during immunotherapy using a CD163-specific nanobody-based immunotracer.
Lauwers Y, De Groof TWM, Vincke C, Van Craenenbroeck J, Jumapili NA, Barthelmess RM, Courtoy G, Waelput W, De Pauw T, Raes G, Devoogdt N, Van Ginderachter JA. Lauwers Y, et al. Among authors: de pauw t. Proc Natl Acad Sci U S A. 2024 Dec 24;121(52):e2409668121. doi: 10.1073/pnas.2409668121. Epub 2024 Dec 18. Proc Natl Acad Sci U S A. 2024. PMID: 39693339 Free PMC article.
Toxicity Profile of eBAT, a Bispecific Ligand-Targeted Toxin Directed to EGFR and uPAR, in Mice and a Clinical Dog Model.
Dicovitsky RH, Schappa JT, Schulte AJ, Lang HP, Kuerbitz E, Roberts S, DePauw TA, Lewellen M, Winter AL, Stuebner K, Buettner M, Reid K, Bergsrud K, Pracht S, Chehadeh A, Feiock C, O'Sullivan MG, Carlson T, Armstrong AR, Meritet D, Henson MS, Weigel BJ, Modiano JF, Borgatti A, Vallera DA. Dicovitsky RH, et al. Toxins (Basel). 2024 Aug 26;16(9):376. doi: 10.3390/toxins16090376. Toxins (Basel). 2024. PMID: 39330834 Free PMC article.
Specific imaging of CD8 + T-Cell dynamics with a nanobody radiotracer against human CD8β.
De Groof TWM, Lauwers Y, De Pauw T, Saxena M, Vincke C, Van Craenenbroeck J, Chapon C, Le Grand R, Raes G, Naninck T, Van Ginderachter JA, Devoogdt N. De Groof TWM, et al. Among authors: de pauw t. Eur J Nucl Med Mol Imaging. 2024 Dec;52(1):193-207. doi: 10.1007/s00259-024-06896-3. Epub 2024 Sep 2. Eur J Nucl Med Mol Imaging. 2024. PMID: 39218831 Free PMC article.
Current status and future expectations of nanobodies in oncology trials.
De Pauw T, De Mey L, Debacker JM, Raes G, Van Ginderachter JA, De Groof TWM, Devoogdt N. De Pauw T, et al. Expert Opin Investig Drugs. 2023 Jul-Dec;32(8):705-721. doi: 10.1080/13543784.2023.2249814. Epub 2023 Aug 28. Expert Opin Investig Drugs. 2023. PMID: 37638538 Review.
13 results