Yang XW - Search Results

1

Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer's Disease Models.

Lee CYD, Daggett A, Gu X, Jiang LL, Langfelder P, Li X, Wang N, Zhao Y, Park CS, Cooper Y, Ferando I, Mody I, Coppola G, Xu H, Yang XW. Lee CYD, et al. Among authors: yang xw. Neuron. 2018 Mar 7;97(5):1032-1048.e5. doi: 10.1016/j.neuron.2018.02.002. Neuron. 2018. PMID: 29518357 Free PMC article.

2

Pathological cell-cell interactions elicited by a neuropathogenic form of mutant Huntingtin contribute to cortical pathogenesis in HD mice.

Gu X, Li C, Wei W, Lo V, Gong S, Li SH, Iwasato T, Itohara S, Li XJ, Mody I, Heintz N, Yang XW. Gu X, et al. Among authors: yang xw. Neuron. 2005 May 5;46(3):433-44. doi: 10.1016/j.neuron.2005.03.025. Neuron. 2005. PMID: 15882643 Free article.

3

Pathological cell-cell interactions are necessary for striatal pathogenesis in a conditional mouse model of Huntington's disease.

Gu X, André VM, Cepeda C, Li SH, Li XJ, Levine MS, Yang XW. Gu X, et al. Among authors: yang xw. Mol Neurodegener. 2007 Apr 30;2:8. doi: 10.1186/1750-1326-2-8. Mol Neurodegener. 2007. PMID: 17470275 Free PMC article.

4

Progressive synaptic pathology of motor cortical neurons in a BAC transgenic mouse model of Huntington's disease.

Spampanato J, Gu X, Yang XW, Mody I. Spampanato J, et al. Among authors: yang xw. Neuroscience. 2008 Dec 2;157(3):606-20. doi: 10.1016/j.neuroscience.2008.09.020. Epub 2008 Sep 18. Neuroscience. 2008. PMID: 18854207 Free PMC article.

5

Serines 13 and 16 are critical determinants of full-length human mutant huntingtin induced disease pathogenesis in HD mice.

Gu X, Greiner ER, Mishra R, Kodali R, Osmand A, Finkbeiner S, Steffan JS, Thompson LM, Wetzel R, Yang XW. Gu X, et al. Among authors: yang xw. Neuron. 2009 Dec 24;64(6):828-40. doi: 10.1016/j.neuron.2009.11.020. Neuron. 2009. PMID: 20064390 Free PMC article.

6

An antisense CAG repeat transcript at JPH3 locus mediates expanded polyglutamine protein toxicity in Huntington's disease-like 2 mice.

Wilburn B, Rudnicki DD, Zhao J, Weitz TM, Cheng Y, Gu X, Greiner E, Park CS, Wang N, Sopher BL, La Spada AR, Osmand A, Margolis RL, Sun YE, Yang XW. Wilburn B, et al. Among authors: yang xw. Neuron. 2011 May 12;70(3):427-40. doi: 10.1016/j.neuron.2011.03.021. Neuron. 2011. PMID: 21555070 Free PMC article.

7

Deletion of astroglial Dicer causes non-cell-autonomous neuronal dysfunction and degeneration.

Tao J, Wu H, Lin Q, Wei W, Lu XH, Cantle JP, Ao Y, Olsen RW, Yang XW, Mody I, Sofroniew MV, Sun YE. Tao J, et al. Among authors: yang xw. J Neurosci. 2011 Jun 1;31(22):8306-19. doi: 10.1523/JNEUROSCI.0567-11.2011. J Neurosci. 2011. PMID: 21632951 Free PMC article.

8

Network organization of the huntingtin proteomic interactome in mammalian brain.

Shirasaki DI, Greiner ER, Al-Ramahi I, Gray M, Boontheung P, Geschwind DH, Botas J, Coppola G, Horvath S, Loo JA, Yang XW. Shirasaki DI, et al. Among authors: yang xw. Neuron. 2012 Jul 12;75(1):41-57. doi: 10.1016/j.neuron.2012.05.024. Neuron. 2012. PMID: 22794259 Free PMC article.

9

Genetic manipulations of mutant huntingtin in mice: new insights into Huntington's disease pathogenesis.

Lee CY, Cantle JP, Yang XW. Lee CY, et al. Among authors: yang xw. FEBS J. 2013 Sep;280(18):4382-94. doi: 10.1111/febs.12418. Epub 2013 Jul 31. FEBS J. 2013. PMID: 23829302 Free PMC article. Review.

10

Huntington's disease: easing the NMDAR traffic jam.

Daggett A, Yang XW. Daggett A, et al. Among authors: yang xw. Nat Med. 2013 Aug;19(8):971-3. doi: 10.1038/nm.3283. Nat Med. 2013. PMID: 23921742 No abstract available.

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