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Page 1
Novel gene variants associated with cardiovascular disease in systemic lupus erythematosus and rheumatoid arthritis.
Leonard D, Svenungsson E, Dahlqvist J, Alexsson A, Ärlestig L, Taylor KE, Sandling JK, Bengtsson C, Frodlund M, Jönsen A, Eketjäll S, Jensen-Urstad K, Gunnarsson I, Sjöwall C, Bengtsson AA, Eloranta ML, Syvänen AC, Rantapää-Dahlqvist S, Criswell LA, Rönnblom L. Leonard D, et al. Among authors: syvanen ac. Ann Rheum Dis. 2018 Jul;77(7):1063-1069. doi: 10.1136/annrheumdis-2017-212614. Epub 2018 Mar 7. Ann Rheum Dis. 2018. PMID: 29514802 Free PMC article.
Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus.
Sigurdsson S, Nordmark G, Göring HH, Lindroos K, Wiman AC, Sturfelt G, Jönsen A, Rantapää-Dahlqvist S, Möller B, Kere J, Koskenmies S, Widén E, Eloranta ML, Julkunen H, Kristjansdottir H, Steinsson K, Alm G, Rönnblom L, Syvänen AC. Sigurdsson S, et al. Among authors: syvanen ac. Am J Hum Genet. 2005 Mar;76(3):528-37. doi: 10.1086/428480. Epub 2005 Jan 18. Am J Hum Genet. 2005. PMID: 15657875 Free PMC article.
Comprehensive evaluation of the genetic variants of interferon regulatory factor 5 (IRF5) reveals a novel 5 bp length polymorphism as strong risk factor for systemic lupus erythematosus.
Sigurdsson S, Göring HH, Kristjansdottir G, Milani L, Nordmark G, Sandling JK, Eloranta ML, Feng D, Sangster-Guity N, Gunnarsson I, Svenungsson E, Sturfelt G, Jönsen A, Truedsson L, Barnes BJ, Alm G, Rönnblom L, Syvänen AC. Sigurdsson S, et al. Among authors: syvanen ac. Hum Mol Genet. 2008 Mar 15;17(6):872-81. doi: 10.1093/hmg/ddm359. Epub 2007 Dec 6. Hum Mol Genet. 2008. PMID: 18063667
A risk haplotype of STAT4 for systemic lupus erythematosus is over-expressed, correlates with anti-dsDNA and shows additive effects with two risk alleles of IRF5.
Sigurdsson S, Nordmark G, Garnier S, Grundberg E, Kwan T, Nilsson O, Eloranta ML, Gunnarsson I, Svenungsson E, Sturfelt G, Bengtsson AA, Jönsen A, Truedsson L, Rantapää-Dahlqvist S, Eriksson C, Alm G, Göring HH, Pastinen T, Syvänen AC, Rönnblom L. Sigurdsson S, et al. Among authors: syvanen ac. Hum Mol Genet. 2008 Sep 15;17(18):2868-76. doi: 10.1093/hmg/ddn184. Epub 2008 Jun 25. Hum Mol Genet. 2008. PMID: 18579578 Free PMC article.
A STAT4 risk allele is associated with ischaemic cerebrovascular events and anti-phospholipid antibodies in systemic lupus erythematosus.
Svenungsson E, Gustafsson J, Leonard D, Sandling J, Gunnarsson I, Nordmark G, Jönsen A, Bengtsson AA, Sturfelt G, Rantapää-Dahlqvist S, Elvin K, Sundin U, Garnier S, Simard JF, Sigurdsson S, Padyukov L, Syvänen AC, Rönnblom L. Svenungsson E, et al. Among authors: syvanen ac. Ann Rheum Dis. 2010 May;69(5):834-40. doi: 10.1136/ard.2009.115535. Epub 2009 Sep 17. Ann Rheum Dis. 2010. PMID: 19762360
HLA-DRB1*04/*13 alleles are associated with vascular disease and antiphospholipid antibodies in systemic lupus erythematosus.
Lundström E, Gustafsson JT, Jönsen A, Leonard D, Zickert A, Elvin K, Sturfelt G, Nordmark G, Bengtsson AA, Sundin U, Källberg H, Sandling JK, Syvänen AC, Klareskog L, Gunnarsson I, Rönnblom L, Padyukov L, Svenungsson E. Lundström E, et al. Among authors: syvanen ac. Ann Rheum Dis. 2013 Jun;72(6):1018-25. doi: 10.1136/annrheumdis-2012-201760. Epub 2012 Aug 14. Ann Rheum Dis. 2013. PMID: 22893315
Genes identified in Asian SLE GWASs are also associated with SLE in Caucasian populations.
Wang C, Ahlford A, Järvinen TM, Nordmark G, Eloranta ML, Gunnarsson I, Svenungsson E, Padyukov L, Sturfelt G, Jönsen A, Bengtsson AA, Truedsson L, Eriksson C, Rantapää-Dahlqvist S, Sjöwall C, Julkunen H, Criswell LA, Graham RR, Behrens TW, Kere J, Rönnblom L, Syvänen AC, Sandling JK. Wang C, et al. Among authors: syvanen ac. Eur J Hum Genet. 2013 Sep;21(9):994-9. doi: 10.1038/ejhg.2012.277. Epub 2012 Dec 19. Eur J Hum Genet. 2013. PMID: 23249952 Free PMC article.
Coronary heart disease in systemic lupus erythematosus is associated with interferon regulatory factor-8 gene variants.
Leonard D, Svenungsson E, Sandling JK, Berggren O, Jönsen A, Bengtsson C, Wang C, Jensen-Urstad K, Granstam SO, Bengtsson AA, Gustafsson JT, Gunnarsson I, Rantapää-Dahlqvist S, Nordmark G, Eloranta ML, Syvänen AC, Rönnblom L. Leonard D, et al. Among authors: syvanen ac. Circ Cardiovasc Genet. 2013 Jun;6(3):255-63. doi: 10.1161/CIRCGENETICS.113.000044. Epub 2013 May 9. Circ Cardiovasc Genet. 2013. PMID: 23661672
350 results