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Pharmacological characterisation of CR6086, a potent prostaglandin E2 receptor 4 antagonist, as a new potential disease-modifying anti-rheumatic drug.
Caselli G, Bonazzi A, Lanza M, Ferrari F, Maggioni D, Ferioli C, Giambelli R, Comi E, Zerbi S, Perrella M, Letari O, Di Luccio E, Colovic M, Persiani S, Zanelli T, Mennuni L, Piepoli T, Rovati LC. Caselli G, et al. Among authors: bonazzi a. Arthritis Res Ther. 2018 Mar 1;20(1):39. doi: 10.1186/s13075-018-1537-8. Arthritis Res Ther. 2018. PMID: 29490676 Free PMC article.
Efficacy and safety of the first-in-class imidazoline-2 receptor ligand CR4056 in pain from knee osteoarthritis and disease phenotypes: a randomized, double-blind, placebo-controlled phase 2 trial.
Rovati LC, Brambilla N, Blicharski T, Connell J, Vitalini C, Bonazzi A, Giacovelli G, Girolami F, D'Amato M. Rovati LC, et al. Among authors: bonazzi a. Osteoarthritis Cartilage. 2020 Jan;28(1):22-30. doi: 10.1016/j.joca.2019.09.002. Epub 2019 Sep 14. Osteoarthritis Cartilage. 2020. PMID: 31526875 Free article. Clinical Trial.
Monoclonal anti-CD18 antibody prevents transcellular biosynthesis of cysteinyl leukotrienes in vitro and in vivo and protects against leukotriene-dependent increase in coronary vascular resistance and myocardial stiffness.
Sala A, Rossoni G, Berti F, Buccellati C, Bonazzi A, Maclouf J, Folco G. Sala A, et al. Among authors: bonazzi a. Circulation. 2000 Mar 28;101(12):1436-40. doi: 10.1161/01.cir.101.12.1436. Circulation. 2000. PMID: 10736289 Free article.
42 results