Mach RH - Search Results

1

Design, synthesis, and in vitro evaluation of quinolinyl analogues for α-synuclein aggregation.

Yue X, Dhavale DD, Li J, Luo Z, Liu J, Yang H, Mach RH, Kotzbauer PT, Tu Z. Yue X, et al. Among authors: mach rh. Bioorg Med Chem Lett. 2018 Apr 1;28(6):1011-1019. doi: 10.1016/j.bmcl.2018.02.031. Epub 2018 Feb 16. Bioorg Med Chem Lett. 2018. PMID: 29482941 Free PMC article.

2

Effect of N-alkylation on the affinities of analogues of spiperone for dopamine D2 and serotonin 5-HT2 receptors.

Mach RH, Jackson JR, Luedtke RR, Ivins KJ, Molinoff PB, Ehrenkaufer RL. Mach RH, et al. J Med Chem. 1992 Feb 7;35(3):423-30. doi: 10.1021/jm00081a002. J Med Chem. 1992. PMID: 1531364

3

Dopamine D-2 receptor imaging radiopharmaceuticals: synthesis, radiolabeling, and in vitro binding of (R)-(+)- and (S)-(-)-3-iodo-2-hydroxy-6-methoxy-N- [(1-ethyl-2-pyrrolidinyl)methyl]benzamide.

Kung HF, Kasliwal R, Pan SG, Kung MP, Mach RH, Guo YZ. Kung HF, et al. Among authors: mach rh. J Med Chem. 1988 May;31(5):1039-43. doi: 10.1021/jm00400a027. J Med Chem. 1988. PMID: 2966245

4

18F-labeled benzamides for studying the dopamine D2 receptor with positron emission tomography.

Mach RH, Luedtke RR, Unsworth CD, Boundy VA, Nowak PA, Scripko JG, Elder ST, Jackson JR, Hoffman PL, Evora PH, et al. Mach RH, et al. J Med Chem. 1993 Nov 12;36(23):3707-20. doi: 10.1021/jm00075a028. J Med Chem. 1993. PMID: 8246241

5

Synthesis of 2-(2,3-dimethoxyphenyl)-4-(aminomethyl)imidazole analogues and their binding affinities for dopamine D(2) and D(3) receptors.

Huang Y, Luedtke RR, Freeman RA, Wu L, Mach RH. Huang Y, et al. Among authors: mach rh. Bioorg Med Chem. 2001 Dec;9(12):3113-22. doi: 10.1016/s0968-0896(01)00175-4. Bioorg Med Chem. 2001. PMID: 11711286

6

Synthesis and structure-activity relationships of N-(1-benzylpiperidin-4-yl)arylacetamide analogues as potent sigma1 receptor ligands.

Huang Y, Hammond PS, Wu L, Mach RH. Huang Y, et al. Among authors: mach rh. J Med Chem. 2001 Dec 6;44(25):4404-15. doi: 10.1021/jm010384j. J Med Chem. 2001. PMID: 11728186

7

Synthesis of 2-(5-bromo-2,3-dimethoxyphenyl)-5-(aminomethyl)-1H-pyrrole analogues and their binding affinities for dopamine D2, D3, and D4 receptors.

Mach RH, Huang Y, Freeman RA, Wu L, Blair S, Luedtke RR. Mach RH, et al. Bioorg Med Chem. 2003 Jan 17;11(2):225-33. doi: 10.1016/s0968-0896(02)00341-3. Bioorg Med Chem. 2003. PMID: 12470717

8

Conformationally-flexible benzamide analogues as dopamine D3 and sigma 2 receptor ligands.

Mach RH, Huang Y, Freeman RA, Wu L, Vangveravong S, Luedtke RR. Mach RH, et al. Bioorg Med Chem Lett. 2004 Jan 5;14(1):195-202. doi: 10.1016/j.bmcl.2003.09.083. Bioorg Med Chem Lett. 2004. PMID: 14684327

9

Synthesis and in vitro binding of N-phenyl piperazine analogs as potential dopamine D3 receptor ligands.

Chu W, Tu Z, McElveen E, Xu J, Taylor M, Luedtke RR, Mach RH. Chu W, et al. Among authors: mach rh. Bioorg Med Chem. 2005 Jan 3;13(1):77-87. doi: 10.1016/j.bmc.2004.09.054. Bioorg Med Chem. 2005. PMID: 15582454

10

Carbon-11 labeled sigma2 receptor ligands for imaging breast cancer.

Tu Z, Dence CS, Ponde DE, Jones L, Wheeler KT, Welch MJ, Mach RH. Tu Z, et al. Among authors: mach rh. Nucl Med Biol. 2005 Jul;32(5):423-30. doi: 10.1016/j.nucmedbio.2005.03.008. Nucl Med Biol. 2005. PMID: 15982571

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