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Page 1
JAK1/JAK2 inhibition by baricitinib in diabetic kidney disease: results from a Phase 2 randomized controlled clinical trial.
Tuttle KR, Brosius FC 3rd, Adler SG, Kretzler M, Mehta RL, Tumlin JA, Tanaka Y, Haneda M, Liu J, Silk ME, Cardillo TE, Duffin KL, Haas JV, Macias WL, Nunes FP, Janes JM. Tuttle KR, et al. Among authors: haas jv. Nephrol Dial Transplant. 2018 Nov 1;33(11):1950-1959. doi: 10.1093/ndt/gfx377. Nephrol Dial Transplant. 2018. PMID: 29481660 Free PMC article. Clinical Trial.
Associations of osteopontin and NT-proBNP with circulating miRNA levels in acute coronary syndrome.
Kwee LC, Neely ML, Grass E, Gregory SG, Roe MT, Ohman EM, Fox KAA, White HD, Armstrong PW, Bowsman LM, Haas JV, Duffin KL, Chan MY, Shah SH. Kwee LC, et al. Among authors: haas jv. Physiol Genomics. 2019 Oct 1;51(10):506-515. doi: 10.1152/physiolgenomics.00033.2019. Epub 2019 Sep 18. Physiol Genomics. 2019. PMID: 31530226 Free PMC article. Clinical Trial.
Effects of pharmacological inhibition of the sodium-dependent phosphate cotransporter 2b (NPT2b) on intestinal phosphate absorption in mouse and rat models.
Wang X, Xu Y, Yu X, Dey A, Zhang HY, Zink CM, Wodka D, Porter G, Matter WF, Porras L, Reidy CA, Peterson JA, Mattioni BE, Haas JV, Kowala MC, Wetterau JR. Wang X, et al. Among authors: haas jv. Pharmacol Res Perspect. 2022 Apr;10(2):e00938. doi: 10.1002/prp2.938. Pharmacol Res Perspect. 2022. PMID: 35194979 Free PMC article.
Genome-wide screen for modulation of hepatic apolipoprotein A-I (ApoA-I) secretion.
Miles RR, Perry W, Haas JV, Mosior MK, N'Cho M, Wang JW, Yu P, Calley J, Yue Y, Carter Q, Han B, Foxworthy P, Kowala MC, Ryan TP, Solenberg PJ, Michael LF. Miles RR, et al. Among authors: haas jv. J Biol Chem. 2013 Mar 1;288(9):6386-96. doi: 10.1074/jbc.M112.410092. Epub 2013 Jan 15. J Biol Chem. 2013. PMID: 23322769 Free PMC article.
The Discovery, Preclinical, and Early Clinical Development of Potent and Selective GPR40 Agonists for the Treatment of Type 2 Diabetes Mellitus (LY2881835, LY2922083, and LY2922470).
Hamdouchi C, Kahl SD, Patel Lewis A, Cardona GR, Zink RW, Chen K, Eessalu TE, Ficorilli JV, Marcelo MC, Otto KA, Wilbur KL, Lineswala JP, Piper JL, Coffey DS, Sweetana SA, Haas JV, Brooks DA, Pratt EJ, Belin RM, Deeg MA, Ma X, Cannady EA, Johnson JT, Yumibe NP, Chen Q, Maiti P, Montrose-Rafizadeh C, Chen Y, Reifel Miller A. Hamdouchi C, et al. Among authors: haas jv. J Med Chem. 2016 Dec 22;59(24):10891-10916. doi: 10.1021/acs.jmedchem.6b00892. Epub 2016 Nov 11. J Med Chem. 2016. PMID: 27749056
Assay Guidance Manual: Quantitative Biology and Pharmacology in Preclinical Drug Discovery.
Coussens NP, Sittampalam GS, Guha R, Brimacombe K, Grossman A, Chung TDY, Weidner JR, Riss T, Trask OJ, Auld D, Dahlin JL, Devanaryan V, Foley TL, McGee J, Kahl SD, Kales SC, Arkin M, Baell J, Bejcek B, Gal-Edd N, Glicksman M, Haas JV, Iversen PW, Hoeppner M, Lathrop S, Sayers E, Liu H, Trawick B, McVey J, Lemmon VP, Li Z, McManus O, Minor L, Napper A, Wildey MJ, Pacifici R, Chin WW, Xia M, Xu X, Lal-Nag M, Hall MD, Michael S, Inglese J, Simeonov A, Austin CP. Coussens NP, et al. Among authors: haas jv. Clin Transl Sci. 2018 Sep;11(5):461-470. doi: 10.1111/cts.12570. Epub 2018 Jul 24. Clin Transl Sci. 2018. PMID: 29877628 Free PMC article. Review.
Discovery of potent small-molecule inhibitors of lipoprotein(a) formation.
Diaz N, Perez C, Escribano AM, Sanz G, Priego J, Lafuente C, Barberis M, Calle L, Espinosa JF, Priest BT, Zhang HY, Nosie AK, Haas JV, Cannady E, Borel A, Schultze AE, Sauder JM, Hendle J, Weichert K, Nicholls SJ, Michael LF. Diaz N, et al. Among authors: haas jv. Nature. 2024 May;629(8013):945-950. doi: 10.1038/s41586-024-07387-z. Epub 2024 May 8. Nature. 2024. PMID: 38720069 Free PMC article.
Basic Guidelines for Reporting Non-Clinical Data.
Dahlin JL, Sittampalam GS, Coussens NP, Devanarayan V, Weidner JR, Iversen PW, Haas JV, Bronson DD, Trask, Jr. OJ, Wiernicki TR, Kahl SD. Dahlin JL, et al. Among authors: haas jv. 2019 Oct 1. In: Markossian S, Grossman A, Arkin M, Auld D, Austin C, Baell J, Brimacombe K, Chung TDY, Coussens NP, Dahlin JL, Devanarayan V, Foley TL, Glicksman M, Gorshkov K, Haas JV, Hall MD, Hoare S, Inglese J, Iversen PW, Lal-Nag M, Li Z, Manro JR, McGee J, McManus O, Pearson M, Riss T, Saradjian P, Sittampalam GS, Tarselli M, Trask OJ Jr, Weidner JR, Wildey MJ, Wilson K, Xia M, Xu X, editors. Assay Guidance Manual [Internet]. Bethesda (MD): Eli Lilly & Company and the National Center for Advancing Translational Sciences; 2004–. 2019 Oct 1. In: Markossian S, Grossman A, Arkin M, Auld D, Austin C, Baell J, Brimacombe K, Chung TDY, Coussens NP, Dahlin JL, Devanarayan V, Foley TL, Glicksman M, Gorshkov K, Haas JV, Hall MD, Hoare S, Inglese J, Iversen PW, Lal-Nag M, Li Z, Manro JR, McGee J, McManus O, Pearson M, Riss T, Saradjian P, Sittampalam GS, Tarselli M, Trask OJ Jr, Weidner JR, Wildey MJ, Wilson K, Xia M, Xu X, editors. Assay Guidance Manual [Internet]. Bethesda (MD): Eli Lilly & Company and the National Center for Advancing Translational Sciences; 2004–. PMID: 31774639 Free Books & Documents. Review.
19 results