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Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation.
Huang H, Weng H, Sun W, Qin X, Shi H, Wu H, Zhao BS, Mesquita A, Liu C, Yuan CL, Hu YC, Hüttelmaier S, Skibbe JR, Su R, Deng X, Dong L, Sun M, Li C, Nachtergaele S, Wang Y, Hu C, Ferchen K, Greis KD, Jiang X, Wei M, Qu L, Guan JL, He C, Yang J, Chen J. Huang H, et al. Among authors: deng x. Nat Cell Biol. 2018 Mar;20(3):285-295. doi: 10.1038/s41556-018-0045-z. Epub 2018 Feb 23. Nat Cell Biol. 2018. PMID: 29476152 Free PMC article.
Role of N6-methyladenosine modification in cancer.
Deng X, Su R, Feng X, Wei M, Chen J. Deng X, et al. Curr Opin Genet Dev. 2018 Feb;48:1-7. doi: 10.1016/j.gde.2017.10.005. Epub 2017 Oct 14. Curr Opin Genet Dev. 2018. PMID: 29040886 Free PMC article. Review.
R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling.
Su R, Dong L, Li C, Nachtergaele S, Wunderlich M, Qing Y, Deng X, Wang Y, Weng X, Hu C, Yu M, Skibbe J, Dai Q, Zou D, Wu T, Yu K, Weng H, Huang H, Ferchen K, Qin X, Zhang B, Qi J, Sasaki AT, Plas DR, Bradner JE, Wei M, Marcucci G, Jiang X, Mulloy JC, Jin J, He C, Chen J. Su R, et al. Among authors: deng x. Cell. 2018 Jan 11;172(1-2):90-105.e23. doi: 10.1016/j.cell.2017.11.031. Epub 2017 Dec 14. Cell. 2018. PMID: 29249359 Free PMC article.
METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification.
Weng H, Huang H, Wu H, Qin X, Zhao BS, Dong L, Shi H, Skibbe J, Shen C, Hu C, Sheng Y, Wang Y, Wunderlich M, Zhang B, Dore LC, Su R, Deng X, Ferchen K, Li C, Sun M, Lu Z, Jiang X, Marcucci G, Mulloy JC, Yang J, Qian Z, Wei M, He C, Chen J. Weng H, et al. Among authors: deng x. Cell Stem Cell. 2018 Feb 1;22(2):191-205.e9. doi: 10.1016/j.stem.2017.11.016. Epub 2017 Dec 28. Cell Stem Cell. 2018. PMID: 29290617 Free PMC article.
Author Correction: Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation.
Huang H, Weng H, Sun W, Qin X, Shi H, Wu H, Zhao BS, Mesquita A, Liu C, Yuan CL, Hu YC, Hüttelmaier S, Skibbe JR, Su R, Deng X, Dong L, Sun M, Li C, Nachtergaele S, Wang Y, Hu C, Ferchen K, Greis KD, Jiang X, Wei M, Qu L, Guan JL, He C, Yang J, Chen J. Huang H, et al. Among authors: deng x. Nat Cell Biol. 2018 Sep;20(9):1098. doi: 10.1038/s41556-018-0102-7. Nat Cell Biol. 2018. PMID: 29880862
Critical Enzymatic Functions of FTO in Obesity and Cancer.
Deng X, Su R, Stanford S, Chen J. Deng X, et al. Front Endocrinol (Lausanne). 2018 Jul 30;9:396. doi: 10.3389/fendo.2018.00396. eCollection 2018. Front Endocrinol (Lausanne). 2018. PMID: 30105001 Free PMC article. Review.
Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally.
Huang H, Weng H, Zhou K, Wu T, Zhao BS, Sun M, Chen Z, Deng X, Xiao G, Auer F, Klemm L, Wu H, Zuo Z, Qin X, Dong Y, Zhou Y, Qin H, Tao S, Du J, Liu J, Lu Z, Yin H, Mesquita A, Yuan CL, Hu YC, Sun W, Su R, Dong L, Shen C, Li C, Qing Y, Jiang X, Wu X, Sun M, Guan JL, Qu L, Wei M, Müschen M, Huang G, He C, Yang J, Chen J. Huang H, et al. Among authors: deng x. Nature. 2019 Mar;567(7748):414-419. doi: 10.1038/s41586-019-1016-7. Epub 2019 Mar 13. Nature. 2019. PMID: 30867593 Free PMC article.
Homoharringtonine exhibits potent anti-tumor effect and modulates DNA epigenome in acute myeloid leukemia by targeting SP1/TET1/5hmC.
Li C, Dong L, Su R, Bi Y, Qing Y, Deng X, Zhou Y, Hu C, Yu M, Huang H, Jiang X, Li X, He X, Zou D, Shen C, Han L, Sun M, Skibbe J, Ferchen K, Qin X, Weng H, Huang H, Song C, Chen J, Jin J. Li C, et al. Among authors: deng x. Haematologica. 2020 Jan;105(1):148-160. doi: 10.3324/haematol.2018.208835. Epub 2019 Apr 11. Haematologica. 2020. PMID: 30975912 Free PMC article.
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