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Assessment of genetic integrity, splenic phagocytosis and cell death potential of (Z)-4-((1,5-dimethyl-3-oxo-2-phenyl-2,3dihydro-1H-pyrazol-4-yl) amino)-4-oxobut-2-enoic acid and its effect when combined with commercial chemotherapeutics.
Oliveira RJ, da Cruz Leite Santos N, Pesarini JR, de Oliveira BC, Berno CR, de Araújo FHS, da Silveira IOMF, Nascimento RO, Brochado Antoniolli-Silva ACM, Duenhas Monreal AC, Beatriz A, de Lima DP, da Silva Gomes R. Oliveira RJ, et al. Among authors: de oliveira bc, de araujo fhs, de lima dp. Genet Mol Biol. 2018 Jan-Mar;41(1):154-166. doi: 10.1590/1678-4685-GMB-2017-0091. Epub 2018 Feb 19. Genet Mol Biol. 2018. PMID: 29473933 Free PMC article.
(4-Methoxyphenyl)(3,4,5-trimethoxyphenyl)methanone inhibits tubulin polymerization, induces G2/M arrest, and triggers apoptosis in human leukemia HL-60 cells.
Magalhães HI, Wilke DV, Bezerra DP, Cavalcanti BC, Rotta R, de Lima DP, Beatriz A, Moraes MO, Diniz-Filho J, Pessoa C. Magalhães HI, et al. Among authors: de lima dp. Toxicol Appl Pharmacol. 2013 Oct 1;272(1):117-26. doi: 10.1016/j.taap.2013.06.001. Epub 2013 Jun 10. Toxicol Appl Pharmacol. 2013. PMID: 23756174
A novel cytosporone 3-Heptyl-4,6-dihydroxy-3H-isobenzofuran-1-one: synthesis; toxicological, apoptotic and immunomodulatory properties; and potentiation of mutagenic damage.
Oliveira RJ, Navarro SD, de Lima DP, Meza A, Pesarini JR, da Silva Gomes R, Karaziack CB, de Oliveira Mauro M, Cunha-Laura AL, Monreal AC, Romão W, Júnior VL, Beatriz A. Oliveira RJ, et al. Among authors: de oliveira mauro m, de lima dp. BMC Cancer. 2015 Jul 31;15:561. doi: 10.1186/s12885-015-1532-2. BMC Cancer. 2015. PMID: 26228542 Free PMC article.
42 results