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Assessment of genetic integrity, splenic phagocytosis and cell death potential of (Z)-4-((1,5-dimethyl-3-oxo-2-phenyl-2,3dihydro-1H-pyrazol-4-yl) amino)-4-oxobut-2-enoic acid and its effect when combined with commercial chemotherapeutics.
Oliveira RJ, da Cruz Leite Santos N, Pesarini JR, de Oliveira BC, Berno CR, de Araújo FHS, da Silveira IOMF, Nascimento RO, Brochado Antoniolli-Silva ACM, Duenhas Monreal AC, Beatriz A, de Lima DP, da Silva Gomes R. Oliveira RJ, et al. Among authors: berno cr. Genet Mol Biol. 2018 Jan-Mar;41(1):154-166. doi: 10.1590/1678-4685-GMB-2017-0091. Epub 2018 Feb 19. Genet Mol Biol. 2018. PMID: 29473933 Free PMC article.
Assessment of the toxicogenic effects and cell death potential of the ester (Z)-methyl 4-((1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)amino)-4-oxobut-2-anoate in combination with cisplatin, cyclophosphamide and doxorubicin.
Juliano Oliveira R, Pereira FPAN, Silveira IOMFD, Lima RV, Berno CR, Pesarini JR, Antoniolli-Silva ACMB, Monreal ACD, Adilson B, Lima DP, Gomes RDS. Juliano Oliveira R, et al. Among authors: berno cr. Genet Mol Biol. 2019 Apr-Jun;42(2):399-410. doi: 10.1590/1678-4685-GMB-2017-0279. Epub 2019 Jun 27. Genet Mol Biol. 2019. PMID: 31259359 Free PMC article.
4-Aminoantipyrine reduces toxic and genotoxic effects of doxorubicin, cisplatin, and cyclophosphamide in male mice.
Berno CR, Rós Bde T, da Silveira IO, Coelho HR, Antoniolli AC, Beatriz A, de Lima DP, Monreal AC, Sousa FG, da Silva Gomes R, Oliveira RJ. Berno CR, et al. Mutat Res Genet Toxicol Environ Mutagen. 2016 Jul;805:19-24. doi: 10.1016/j.mrgentox.2016.05.009. Epub 2016 May 20. Mutat Res Genet Toxicol Environ Mutagen. 2016. PMID: 27402479 Free article.