Ruszczycky MW - Search Results

1

Mechanistic Implications of the Deamination of TDP-4-amino-4-deoxy-d-fucose Catalyzed by the Radical SAM Enzyme DesII.

Ko Y, Lin GM, Ruszczycky MW, Liu HW. Ko Y, et al. Among authors: ruszczycky mw. Biochemistry. 2018 Jun 5;57(22):3130-3133. doi: 10.1021/acs.biochem.8b00110. Epub 2018 Feb 28. Biochemistry. 2018. PMID: 29473739 Free PMC article.

2

Characterization and mechanistic studies of DesII: a radical S-adenosyl-L-methionine enzyme involved in the biosynthesis of TDP-D-desosamine.

Szu PH, Ruszczycky MW, Choi SH, Yan F, Liu HW. Szu PH, et al. Among authors: ruszczycky mw. J Am Chem Soc. 2009 Oct 7;131(39):14030-42. doi: 10.1021/ja903354k. J Am Chem Soc. 2009. PMID: 19746907 Free PMC article.

3

Stoichiometry of the redox neutral deamination and oxidative dehydrogenation reactions catalyzed by the radical SAM enzyme DesII.

Ruszczycky MW, Choi SH, Liu HW. Ruszczycky MW, et al. J Am Chem Soc. 2010 Feb 24;132(7):2359-69. doi: 10.1021/ja909451a. J Am Chem Soc. 2010. PMID: 20121093 Free PMC article.

4

Mechanistic studies of the radical S-adenosyl-L-methionine enzyme DesII: EPR characterization of a radical intermediate generated during its catalyzed dehydrogenation of TDP-D-quinovose.

Ruszczycky MW, Choi SH, Mansoorabadi SO, Liu HW. Ruszczycky MW, et al. J Am Chem Soc. 2011 May 18;133(19):7292-5. doi: 10.1021/ja201212f. Epub 2011 Apr 22. J Am Chem Soc. 2011. PMID: 21513273 Free PMC article.

5

Enzyme-catalysed [4+2] cycloaddition is a key step in the biosynthesis of spinosyn A.

Kim HJ, Ruszczycky MW, Choi SH, Liu YN, Liu HW. Kim HJ, et al. Among authors: ruszczycky mw. Nature. 2011 May 5;473(7345):109-12. doi: 10.1038/nature09981. Nature. 2011. PMID: 21544146 Free PMC article.

6

A fluoro analogue of UDP-α-D-glucuronic acid is an inhibitor of UDP-α-D-apiose/UDP-α-D-xylose synthase.

Choi SH, Ruszczycky MW, Zhang H, Liu HW. Choi SH, et al. Among authors: ruszczycky mw. Chem Commun (Camb). 2011 Sep 28;47(36):10130-2. doi: 10.1039/c1cc13140k. Epub 2011 Aug 9. Chem Commun (Camb). 2011. PMID: 21826368

7

Radical SAM enzymes in the biosynthesis of sugar-containing natural products.

Ruszczycky MW, Ogasawara Y, Liu HW. Ruszczycky MW, et al. Biochim Biophys Acta. 2012 Nov;1824(11):1231-44. doi: 10.1016/j.bbapap.2011.11.006. Epub 2011 Dec 7. Biochim Biophys Acta. 2012. PMID: 22172915 Free PMC article. Review.

8

Nucleophilic participation of reduced flavin coenzyme in mechanism of UDP-galactopyranose mutase.

Sun HG, Ruszczycky MW, Chang WC, Thibodeaux CJ, Liu HW. Sun HG, et al. Among authors: ruszczycky mw. J Biol Chem. 2012 Feb 10;287(7):4602-8. doi: 10.1074/jbc.M111.312538. Epub 2011 Dec 20. J Biol Chem. 2012. PMID: 22187430 Free PMC article.

9

Current developments and challenges in the search for a naturally selected Diels-Alderase.

Kim HJ, Ruszczycky MW, Liu HW. Kim HJ, et al. Among authors: ruszczycky mw. Curr Opin Chem Biol. 2012 Apr;16(1-2):124-31. doi: 10.1016/j.cbpa.2011.12.017. Epub 2012 Jan 17. Curr Opin Chem Biol. 2012. PMID: 22260931 Free PMC article. Review.

10

EPR-kinetic isotope effect study of the mechanism of radical-mediated dehydrogenation of an alcohol by the radical SAM enzyme DesII.

Ruszczycky MW, Choi SH, Liu HW. Ruszczycky MW, et al. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2088-93. doi: 10.1073/pnas.1209446110. Epub 2013 Jan 17. Proc Natl Acad Sci U S A. 2013. PMID: 23329328 Free PMC article.

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