Wold EA - Search Results

1

Therapeutic Potential of Oridonin and Its Analogs: From Anticancer and Antiinflammation to Neuroprotection.

Xu J, Wold EA, Ding Y, Shen Q, Zhou J. Xu J, et al. Among authors: wold ea. Molecules. 2018 Feb 22;23(2):474. doi: 10.3390/molecules23020474. Molecules. 2018. PMID: 29470395 Free PMC article. Review.

2

BH4 domain of Bcl-2 as a novel target for cancer therapy.

Liu Z, Wild C, Ding Y, Ye N, Chen H, Wold EA, Zhou J. Liu Z, et al. Among authors: wold ea. Drug Discov Today. 2016 Jun;21(6):989-96. doi: 10.1016/j.drudis.2015.11.008. Epub 2015 Nov 26. Drug Discov Today. 2016. PMID: 26631752 Free PMC article. Review.

3

Discovery and development of natural product oridonin-inspired anticancer agents.

Ding Y, Ding C, Ye N, Liu Z, Wold EA, Chen H, Wild C, Shen Q, Zhou J. Ding Y, et al. Among authors: wold ea. Eur J Med Chem. 2016 Oct 21;122:102-117. doi: 10.1016/j.ejmech.2016.06.015. Epub 2016 Jun 13. Eur J Med Chem. 2016. PMID: 27344488 Free PMC article. Review.

4

Therapeutic Potential of Spirooxindoles as Antiviral Agents.

Ye N, Chen H, Wold EA, Shi PY, Zhou J. Ye N, et al. Among authors: wold ea. ACS Infect Dis. 2016 Jun 10;2(6):382-92. doi: 10.1021/acsinfecdis.6b00041. Epub 2016 May 5. ACS Infect Dis. 2016. PMID: 27627626 Free PMC article. Review.

5

Drug Discovery Targeting Bromodomain-Containing Protein 4.

Liu Z, Wang P, Chen H, Wold EA, Tian B, Brasier AR, Zhou J. Liu Z, et al. Among authors: wold ea. J Med Chem. 2017 Jun 8;60(11):4533-4558. doi: 10.1021/acs.jmedchem.6b01761. Epub 2017 Mar 2. J Med Chem. 2017. PMID: 28195723 Free PMC article. Review.

6

Regio- and Stereospecific Synthesis of Oridonin D-Ring Aziridinated Analogues for the Treatment of Triple-Negative Breast Cancer via Mediated Irreversible Covalent Warheads.

Ding Y, Li D, Ding C, Wang P, Liu Z, Wold EA, Ye N, Chen H, White MA, Shen Q, Zhou J. Ding Y, et al. Among authors: wold ea. J Med Chem. 2018 Apr 12;61(7):2737-2752. doi: 10.1021/acs.jmedchem.7b01514. Epub 2018 Mar 20. J Med Chem. 2018. PMID: 29528645 Free PMC article.

7

Design, Synthesis, and Characterization of 4-Undecylpiperidine-2-carboxamides as Positive Allosteric Modulators of the Serotonin (5-HT) 5-HT_2C Receptor.

Wild CT, Miszkiel JM, Wold EA, Soto CA, Ding C, Hartley RM, White MA, Anastasio NC, Cunningham KA, Zhou J. Wild CT, et al. Among authors: wold ea. J Med Chem. 2019 Jan 10;62(1):288-305. doi: 10.1021/acs.jmedchem.8b00401. Epub 2018 Apr 13. J Med Chem. 2019. PMID: 29620897 Free PMC article.

8

Allosteric Modulation of Class A GPCRs: Targets, Agents, and Emerging Concepts.

Wold EA, Chen J, Cunningham KA, Zhou J. Wold EA, et al. J Med Chem. 2019 Jan 10;62(1):88-127. doi: 10.1021/acs.jmedchem.8b00875. Epub 2018 Aug 28. J Med Chem. 2019. PMID: 30106578 Free PMC article. Review.

9

Orphan Receptor GPR88 as an Emerging Neurotherapeutic Target.

Ye N, Li B, Mao Q, Wold EA, Tian S, Allen JA, Zhou J. Ye N, et al. Among authors: wold ea. ACS Chem Neurosci. 2019 Jan 16;10(1):190-200. doi: 10.1021/acschemneuro.8b00572. Epub 2018 Dec 20. ACS Chem Neurosci. 2019. PMID: 30540906 Free PMC article. Review.

10

GPCR Allosteric Modulators: Mechanistic Advantages and Therapeutic Applications.

Wold EA, Zhou J. Wold EA, et al. Curr Top Med Chem. 2018;18(23):2002-2006. doi: 10.2174/1568026619999190101151837. Curr Top Med Chem. 2018. PMID: 30621563 Free PMC article.

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