Drennan CL - Search Results

1

3.3-Å resolution cryo-EM structure of human ribonucleotide reductase with substrate and allosteric regulators bound.

Brignole EJ, Tsai KL, Chittuluru J, Li H, Aye Y, Penczek PA, Stubbe J, Drennan CL, Asturias F. Brignole EJ, et al. Among authors: drennan cl. Elife. 2018 Feb 20;7:e31502. doi: 10.7554/eLife.31502. Elife. 2018. PMID: 29460780 Free PMC article.

2

The crystal structure of class II ribonucleotide reductase reveals how an allosterically regulated monomer mimics a dimer.

Sintchak MD, Arjara G, Kellogg BA, Stubbe J, Drennan CL. Sintchak MD, et al. Among authors: drennan cl. Nat Struct Biol. 2002 Apr;9(4):293-300. doi: 10.1038/nsb774. Nat Struct Biol. 2002. PMID: 11875520

3

Structural interconversions modulate activity of Escherichia coli ribonucleotide reductase.

Ando N, Brignole EJ, Zimanyi CM, Funk MA, Yokoyama K, Asturias FJ, Stubbe J, Drennan CL. Ando N, et al. Among authors: drennan cl. Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21046-51. doi: 10.1073/pnas.1112715108. Epub 2011 Dec 12. Proc Natl Acad Sci U S A. 2011. PMID: 22160671 Free PMC article.

4

The prototypic class Ia ribonucleotide reductase from Escherichia coli: still surprising after all these years.

Brignole EJ, Ando N, Zimanyi CM, Drennan CL. Brignole EJ, et al. Among authors: drennan cl. Biochem Soc Trans. 2012 Jun 1;40(3):523-30. doi: 10.1042/BST20120081. Biochem Soc Trans. 2012. PMID: 22616862 Free PMC article. Review.

5

Tangled up in knots: structures of inactivated forms of E. coli class Ia ribonucleotide reductase.

Zimanyi CM, Ando N, Brignole EJ, Asturias FJ, Stubbe J, Drennan CL. Zimanyi CM, et al. Among authors: drennan cl. Structure. 2012 Aug 8;20(8):1374-83. doi: 10.1016/j.str.2012.05.009. Epub 2012 Jun 21. Structure. 2012. PMID: 22727814 Free PMC article.

6

Clofarabine targets the large subunit (α) of human ribonucleotide reductase in live cells by assembly into persistent hexamers.

Aye Y, Brignole EJ, Long MJ, Chittuluru J, Drennan CL, Asturias FJ, Stubbe J. Aye Y, et al. Among authors: drennan cl. Chem Biol. 2012 Jul 27;19(7):799-805. doi: 10.1016/j.chembiol.2012.05.015. Chem Biol. 2012. PMID: 22840768 Free PMC article.

7

Generation of a stable, aminotyrosyl radical-induced α2β2 complex of Escherichia coli class Ia ribonucleotide reductase.

Minnihan EC, Ando N, Brignole EJ, Olshansky L, Chittuluru J, Asturias FJ, Drennan CL, Nocera DG, Stubbe J. Minnihan EC, et al. Among authors: drennan cl. Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):3835-40. doi: 10.1073/pnas.1220691110. Epub 2013 Feb 19. Proc Natl Acad Sci U S A. 2013. PMID: 23431160 Free PMC article.

8

The class III ribonucleotide reductase from Neisseria bacilliformis can utilize thioredoxin as a reductant.

Wei Y, Funk MA, Rosado LA, Baek J, Drennan CL, Stubbe J. Wei Y, et al. Among authors: drennan cl. Proc Natl Acad Sci U S A. 2014 Sep 9;111(36):E3756-65. doi: 10.1073/pnas.1414396111. Epub 2014 Aug 25. Proc Natl Acad Sci U S A. 2014. PMID: 25157154 Free PMC article.

9

An epitope tag alters phosphoglycerate dehydrogenase structure and impairs ability to support cell proliferation.

Mattaini KR, Brignole EJ, Kini M, Davidson SM, Fiske BP, Drennan CL, Vander Heiden MG. Mattaini KR, et al. Among authors: drennan cl. Cancer Metab. 2015 Apr 29;3:5. doi: 10.1186/s40170-015-0131-7. eCollection 2015. Cancer Metab. 2015. PMID: 25926973 Free PMC article.

10

The Structure of an Oxalate Oxidoreductase Provides Insight into Microbial 2-Oxoacid Metabolism.

Gibson MI, Brignole EJ, Pierce E, Can M, Ragsdale SW, Drennan CL. Gibson MI, et al. Among authors: drennan cl. Biochemistry. 2015 Jul 7;54(26):4112-20. doi: 10.1021/acs.biochem.5b00521. Epub 2015 Jun 24. Biochemistry. 2015. PMID: 26061898 Free PMC article.

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