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Page 1
Transcriptional regulation by NR5A2 links differentiation and inflammation in the pancreas.
Cobo I, Martinelli P, Flández M, Bakiri L, Zhang M, Carrillo-de-Santa-Pau E, Jia J, Sánchez-Arévalo Lobo VJ, Megías D, Felipe I, Del Pozo N, Millán I, Thommesen L, Bruland T, Olson SH, Smith J, Schoonjans K, Bamlet WR, Petersen GM, Malats N, Amundadottir LT, Wagner EF, Real FX. Cobo I, et al. Among authors: megias d. Nature. 2018 Feb 22;554(7693):533-537. doi: 10.1038/nature25751. Epub 2018 Feb 14. Nature. 2018. PMID: 29443959 Free PMC article.
Reprogramming in vivo produces teratomas and iPS cells with totipotency features.
Abad M, Mosteiro L, Pantoja C, Cañamero M, Rayon T, Ors I, Graña O, Megías D, Domínguez O, Martínez D, Manzanares M, Ortega S, Serrano M. Abad M, et al. Among authors: megias d. Nature. 2013 Oct 17;502(7471):340-5. doi: 10.1038/nature12586. Epub 2013 Sep 11. Nature. 2013. PMID: 24025773
RAB7 controls melanoma progression by exploiting a lineage-specific wiring of the endolysosomal pathway.
Alonso-Curbelo D, Riveiro-Falkenbach E, Pérez-Guijarro E, Cifdaloz M, Karras P, Osterloh L, Megías D, Cañón E, Calvo TG, Olmeda D, Gómez-López G, Graña O, Sánchez-Arévalo Lobo VJ, Pisano DG, Wang HW, Ortiz-Romero P, Tormo D, Hoek K, Rodríguez-Peralto JL, Joyce JA, Soengas MS. Alonso-Curbelo D, et al. Among authors: megias d. Cancer Cell. 2014 Jul 14;26(1):61-76. doi: 10.1016/j.ccr.2014.04.030. Epub 2014 Jun 26. Cancer Cell. 2014. PMID: 24981740 Free article.
Intracellular autofluorescence: a biomarker for epithelial cancer stem cells.
Miranda-Lorenzo I, Dorado J, Lonardo E, Alcala S, Serrano AG, Clausell-Tormos J, Cioffi M, Megias D, Zagorac S, Balic A, Hidalgo M, Erkan M, Kleeff J, Scarpa A, Sainz B Jr, Heeschen C. Miranda-Lorenzo I, et al. Among authors: megias d. Nat Methods. 2014 Nov;11(11):1161-9. doi: 10.1038/nmeth.3112. Epub 2014 Sep 28. Nat Methods. 2014. PMID: 25262208
Lineage-specific roles of the cytoplasmic polyadenylation factor CPEB4 in the regulation of melanoma drivers.
Pérez-Guijarro E, Karras P, Cifdaloz M, Martínez-Herranz R, Cañón E, Graña O, Horcajada-Reales C, Alonso-Curbelo D, Calvo TG, Gómez-López G, Bellora N, Riveiro-Falkenbach E, Ortiz-Romero PL, Rodríguez-Peralto JL, Maestre L, Roncador G, de Agustín Asensio JC, Goding CR, Eyras E, Megías D, Méndez R, Soengas MS. Pérez-Guijarro E, et al. Among authors: megias d. Nat Commun. 2016 Nov 18;7:13418. doi: 10.1038/ncomms13418. Nat Commun. 2016. PMID: 27857118 Free PMC article.
Systems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the RNA binding protein CELF1.
Cifdaloz M, Osterloh L, Graña O, Riveiro-Falkenbach E, Ximénez-Embún P, Muñoz J, Tejedo C, Calvo TG, Karras P, Olmeda D, Miñana B, Gómez-López G, Cañon E, Eyras E, Guo H, Kappes F, Ortiz-Romero PL, Rodríguez-Peralto JL, Megías D, Valcárcel J, Soengas MS. Cifdaloz M, et al. Among authors: megias d. Nat Commun. 2017 Dec 21;8(1):2249. doi: 10.1038/s41467-017-02353-y. Nat Commun. 2017. PMID: 29269732 Free PMC article.
STAT3 labels a subpopulation of reactive astrocytes required for brain metastasis.
Priego N, Zhu L, Monteiro C, Mulders M, Wasilewski D, Bindeman W, Doglio L, Martínez L, Martínez-Saez E, Ramón Y Cajal S, Megías D, Hernández-Encinas E, Blanco-Aparicio C, Martínez L, Zarzuela E, Muñoz J, Fustero-Torre C, Piñeiro-Yáñez E, Hernández-Laín A, Bertero L, Poli V, Sanchez-Martinez M, Menendez JA, Soffietti R, Bosch-Barrera J, Valiente M. Priego N, et al. Among authors: megias d. Nat Med. 2018 Jul;24(7):1024-1035. doi: 10.1038/s41591-018-0044-4. Epub 2018 Jun 11. Nat Med. 2018. PMID: 29892069 Free article.
Fra-2-expressing macrophages promote lung fibrosis in mice.
Ucero AC, Bakiri L, Roediger B, Suzuki M, Jimenez M, Mandal P, Braghetta P, Bonaldo P, Paz-Ares L, Fustero-Torre C, Ximenez-Embun P, Hernandez AI, Megias D, Wagner EF. Ucero AC, et al. Among authors: megias d. J Clin Invest. 2019 May 28;129(8):3293-3309. doi: 10.1172/JCI125366. J Clin Invest. 2019. PMID: 31135379 Free PMC article.
Role of bulge epidermal stem cells and TSLP signaling in psoriasis.
Gago-Lopez N, Mellor LF, Megías D, Martín-Serrano G, Izeta A, Jimenez F, Wagner EF. Gago-Lopez N, et al. Among authors: megias d. EMBO Mol Med. 2019 Nov 7;11(11):e10697. doi: 10.15252/emmm.201910697. Epub 2019 Sep 26. EMBO Mol Med. 2019. PMID: 31556482 Free PMC article.
122 results