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Aging is associated with a systemic length-associated transcriptome imbalance.
Stoeger T, Grant RA, McQuattie-Pimentel AC, Anekalla KR, Liu SS, Tejedor-Navarro H, Singer BD, Abdala-Valencia H, Schwake M, Tetreault MP, Perlman H, Balch WE, Chandel NS, Ridge KM, Sznajder JI, Morimoto RI, Misharin AV, Budinger GRS, Nunes Amaral LA. Stoeger T, et al. Among authors: grant ra. Nat Aging. 2022 Dec;2(12):1191-1206. doi: 10.1038/s43587-022-00317-6. Epub 2022 Dec 9. Nat Aging. 2022. PMID: 37118543 Free PMC article.
Prolonged exposure to lung-derived cytokines is associated with inflammatory activation of microglia in patients with COVID-19.
Grant RA, Poor TA, Sichizya L, Diaz E, Bailey JI, Soni S, Senkow KJ, Pérez-Leonor XG, Abdala-Valencia H, Lu Z, Donnelly HK, Tighe RM, Lomasney JW, Wunderink RG, Singer BD, Misharin AV, Budinger GS. Grant RA, et al. bioRxiv [Preprint]. 2023 Jul 28:2023.07.28.550765. doi: 10.1101/2023.07.28.550765. bioRxiv. 2023. Update in: JCI Insight. 2024 Mar 19;9(8):e178859. doi: 10.1172/jci.insight.178859 PMID: 37546860 Free PMC article. Updated. Preprint.
Nuclear receptor signaling via NHR-49/MDT-15 regulates stress resilience and proteostasis in response to reproductive and metabolic cues.
Sala AJ, Grant RA, Imran G, Morton C, Brielmann RM, Bott LC, Watts J, Morimoto RI. Sala AJ, et al. bioRxiv [Preprint]. 2023 Apr 25:2023.04.25.537803. doi: 10.1101/2023.04.25.537803. bioRxiv. 2023. Update in: Genes Dev. 2024 Jun 25;38(9-10):380-392. doi: 10.1101/gad.351829.124 PMID: 37162952 Free PMC article. Updated. Preprint.
Circuits between infected macrophages and T cells in SARS-CoV-2 pneumonia.
Grant RA, Morales-Nebreda L, Markov NS, Swaminathan S, Querrey M, Guzman ER, Abbott DA, Donnelly HK, Donayre A, Goldberg IA, Klug ZM, Borkowski N, Lu Z, Kihshen H, Politanska Y, Sichizya L, Kang M, Shilatifard A, Qi C, Lomasney JW, Argento AC, Kruser JM, Malsin ES, Pickens CO, Smith SB, Walter JM, Pawlowski AE, Schneider D, Nannapaneni P, Abdala-Valencia H, Bharat A, Gottardi CJ, Budinger GRS, Misharin AV, Singer BD, Wunderink RG; NU SCRIPT Study Investigators. Grant RA, et al. Nature. 2021 Feb;590(7847):635-641. doi: 10.1038/s41586-020-03148-w. Epub 2021 Jan 11. Nature. 2021. PMID: 33429418 Free PMC article.
Machine learning links unresolving secondary pneumonia to mortality in patients with severe pneumonia, including COVID-19.
Gao CA, Markov NS, Stoeger T, Pawlowski A, Kang M, Nannapaneni P, Grant RA, Pickens C, Walter JM, Kruser JM, Rasmussen L, Schneider D, Starren J, Donnelly HK, Donayre A, Luo Y, Budinger GRS, Wunderink RG, Misharin AV, Singer BD; NU SCRIPT Study Investigators. Gao CA, et al. Among authors: grant ra. J Clin Invest. 2023 Jun 15;133(12):e170682. doi: 10.1172/JCI170682. J Clin Invest. 2023. PMID: 37104035 Free PMC article.
Prolonged exposure to lung-derived cytokines is associated with activation of microglia in patients with COVID-19.
Grant RA, Poor TA, Sichizya L, Diaz E, Bailey JI, Soni S, Senkow KJ, Pérez-Leonor XG, Abdala-Valencia H, Lu Z, Donnelly HK, Simons LM, Ozer EA, Tighe RM, Lomasney JW, Wunderink RG, Singer BD, Misharin AV, Budinger GRS; Northwestern University Successful Clinical Response In Pneumonia Therapy (NU SCRIPT) Investigators. Grant RA, et al. JCI Insight. 2024 Mar 19;9(8):e178859. doi: 10.1172/jci.insight.178859. JCI Insight. 2024. PMID: 38502186 Free PMC article.
2,402 results