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Convergent Therapeutic Strategies to Overcome the Heterogeneity of Acquired Resistance in BRAFV600E Colorectal Cancer.
Hazar-Rethinam M, Kleyman M, Han GC, Liu D, Ahronian LG, Shahzade HA, Chen L, Parikh AR, Allen JN, Clark JW, Kwak EL, Faris JE, Murphy JE, Hong TS, Van Seventer EE, Nadres B, Hong CB, Gurski JM Jr, Jessop NA, Dias-Santagata D, Iafrate AJ, Van Allen EM, Corcoran RB. Hazar-Rethinam M, et al. Among authors: kleyman m. Cancer Discov. 2018 Apr;8(4):417-427. doi: 10.1158/2159-8290.CD-17-1227. Epub 2018 Feb 5. Cancer Discov. 2018. PMID: 29431697 Free PMC article.
B Cells Promote Pancreatic Tumorigenesis.
Roghanian A, Fraser C, Kleyman M, Chen J. Roghanian A, et al. Among authors: kleyman m. Cancer Discov. 2016 Mar;6(3):230-2. doi: 10.1158/2159-8290.CD-16-0100. Cancer Discov. 2016. PMID: 26951836 Free article.
Naturally occurring dominant resistance mutations to hepatitis C virus protease and polymerase inhibitors in treatment-naïve patients.
Kuntzen T, Timm J, Berical A, Lennon N, Berlin AM, Young SK, Lee B, Heckerman D, Carlson J, Reyor LL, Kleyman M, McMahon CM, Birch C, Schulze Zur Wiesch J, Ledlie T, Koehrsen M, Kodira C, Roberts AD, Lauer GM, Rosen HR, Bihl F, Cerny A, Spengler U, Liu Z, Kim AY, Xing Y, Schneidewind A, Madey MA, Fleckenstein JF, Park VM, Galagan JE, Nusbaum C, Walker BD, Lake-Bakaar GV, Daar ES, Jacobson IM, Gomperts ED, Edlin BR, Donfield SM, Chung RT, Talal AH, Marion T, Birren BW, Henn MR, Allen TM. Kuntzen T, et al. Among authors: kleyman m. Hepatology. 2008 Dec;48(6):1769-78. doi: 10.1002/hep.22549. Hepatology. 2008. PMID: 19026009 Free PMC article.
Anticancer immunity induced by a synthetic tumor-targeted CD137 agonist.
Upadhyaya P, Lahdenranta J, Hurov K, Battula S, Dods R, Haines E, Kleyman M, Kristensson J, Kublin J, Lani R, Ma J, Mudd G, Repash E, Van Rietschoten K, Stephen T, You F, Harrison H, Chen L, McDonnell K, Brandish P, Keen N. Upadhyaya P, et al. Among authors: kleyman m. J Immunother Cancer. 2021 Jan;9(1):e001762. doi: 10.1136/jitc-2020-001762. J Immunother Cancer. 2021. PMID: 33500260 Free PMC article.
MFSD7C switches mitochondrial ATP synthesis to thermogenesis in response to heme.
Li Y, Ivica NA, Dong T, Papageorgiou DP, He Y, Brown DR, Kleyman M, Hu G, Chen WW, Sullivan LB, Del Rosario A, Hammond PT, Vander Heiden MG, Chen J. Li Y, et al. Among authors: kleyman m. Nat Commun. 2020 Sep 24;11(1):4837. doi: 10.1038/s41467-020-18607-1. Nat Commun. 2020. PMID: 32973183 Free PMC article.
An mRNA-based platform for the delivery of pathogen-specific IgA into mucosal secretions.
Deal CE, Richards AF, Yeung T, Maron MJ, Wang Z, Lai YT, Fritz BR, Himansu S, Narayanan E, Liu D, Koleva R, Licht S, Hsiao CJ, Rajlic IL, Koch H, Kleyman M, Pulse ME, Weiss WJ, Doering JE, Lindberg SK, Mantis NJ, Carfi A, Plante OJ. Deal CE, et al. Among authors: kleyman m. Cell Rep Med. 2023 Nov 21;4(11):101253. doi: 10.1016/j.xcrm.2023.101253. Epub 2023 Nov 1. Cell Rep Med. 2023. PMID: 37918405 Free PMC article.
Artificial Intelligence, Healthcare, Clinical Genomics, and Pharmacogenomics Approaches in Precision Medicine.
Abdelhalim H, Berber A, Lodi M, Jain R, Nair A, Pappu A, Patel K, Venkat V, Venkatesan C, Wable R, Dinatale M, Fu A, Iyer V, Kalove I, Kleyman M, Koutsoutis J, Menna D, Paliwal M, Patel N, Patel T, Rafique Z, Samadi R, Varadhan R, Bolla S, Vadapalli S, Ahmed Z. Abdelhalim H, et al. Among authors: kleyman m. Front Genet. 2022 Jul 6;13:929736. doi: 10.3389/fgene.2022.929736. eCollection 2022. Front Genet. 2022. PMID: 35873469 Free PMC article. Review.
18 results