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[11C](R)-Rolipram positron emission tomography detects DISC1 inhibition of phosphodiesterase type 4 in live Disc1 locus-impaired mice.
Ooms M, Tsujikawa T, Lohith TG, Mabins SN, Zoghbi SS, Sumitomo A, Jaaro-Peled H, Kimura Y, Telu S, Pike VW, Tomoda T, Innis RB, Sawa A, Fujita M. Ooms M, et al. Among authors: lohith tg. J Cereb Blood Flow Metab. 2019 Jul;39(7):1306-1313. doi: 10.1177/0271678X18758997. Epub 2018 Feb 12. J Cereb Blood Flow Metab. 2019. PMID: 29430995 Free PMC article.
Evaluation of novel N1-methyl-2-phenylindol-3-ylglyoxylamides as a new chemotype of 18 kDa translocator protein-selective ligand suitable for the development of positron emission tomography radioligands.
Pike VW, Taliani S, Lohith TG, Owen DR, Pugliesi I, Da Pozzo E, Hong J, Zoghbi SS, Gunn RN, Parker CA, Rabiner EA, Fujita M, Innis RB, Martini C, Da Settimo F. Pike VW, et al. Among authors: lohith tg. J Med Chem. 2011 Jan 13;54(1):366-73. doi: 10.1021/jm101230g. Epub 2010 Dec 6. J Med Chem. 2011. PMID: 21133364 Free PMC article.
Brain and whole-body imaging in rhesus monkeys of 11C-NOP-1A, a promising PET radioligand for nociceptin/orphanin FQ peptide receptors.
Kimura Y, Fujita M, Hong J, Lohith TG, Gladding RL, Zoghbi SS, Tauscher JA, Goebl N, Rash KS, Chen Z, Pedregal C, Barth VN, Pike VW, Innis RB. Kimura Y, et al. Among authors: lohith tg. J Nucl Med. 2011 Oct;52(10):1638-45. doi: 10.2967/jnumed.111.091181. Epub 2011 Aug 30. J Nucl Med. 2011. PMID: 21880575 Free PMC article.
11C-ER176, a Radioligand for 18-kDa Translocator Protein, Has Adequate Sensitivity to Robustly Image All Three Affinity Genotypes in Human Brain.
Ikawa M, Lohith TG, Shrestha S, Telu S, Zoghbi SS, Castellano S, Taliani S, Da Settimo F, Fujita M, Pike VW, Innis RB; Biomarkers Consortium Radioligand Project Team. Ikawa M, et al. Among authors: lohith tg. J Nucl Med. 2017 Feb;58(2):320-325. doi: 10.2967/jnumed.116.178996. Epub 2016 Nov 17. J Nucl Med. 2017. PMID: 27856631 Free PMC article.
25 results