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Page 1
Structural stability of purified human CFTR is systematically improved by mutations in nucleotide binding domain 1.
Yang Z, Hildebrandt E, Jiang F, Aleksandrov AA, Khazanov N, Zhou Q, An J, Mezzell AT, Xavier BM, Ding H, Riordan JR, Senderowitz H, Kappes JC, Brouillette CG, Urbatsch IL. Yang Z, et al. Among authors: urbatsch il. Biochim Biophys Acta Biomembr. 2018 May;1860(5):1193-1204. doi: 10.1016/j.bbamem.2018.02.006. Epub 2018 Feb 7. Biochim Biophys Acta Biomembr. 2018. PMID: 29425673 Free PMC article.
A stable human-cell system overexpressing cystic fibrosis transmembrane conductance regulator recombinant protein at the cell surface.
Hildebrandt E, Mulky A, Ding H, Dai Q, Aleksandrov AA, Bajrami B, Diego PA, Wu X, Ray M, Naren AP, Riordan JR, Yao X, DeLucas LJ, Urbatsch IL, Kappes JC. Hildebrandt E, et al. Among authors: urbatsch il. Mol Biotechnol. 2015 May;57(5):391-405. doi: 10.1007/s12033-014-9830-5. Mol Biotechnol. 2015. PMID: 25577540 Free PMC article.
Interactions and cooperativity between P-glycoprotein structural domains determined by thermal unfolding provides insights into its solution structure and function.
Yang Z, Zhou Q, Mok L, Singh A, Swartz DJ, Urbatsch IL, Brouillette CG. Yang Z, et al. Among authors: urbatsch il. Biochim Biophys Acta Biomembr. 2017 Jan;1859(1):48-60. doi: 10.1016/j.bbamem.2016.10.009. Epub 2016 Oct 23. Biochim Biophys Acta Biomembr. 2017. PMID: 27783926 Free PMC article.
Specific stabilization of CFTR by phosphatidylserine.
Hildebrandt E, Khazanov N, Kappes JC, Dai Q, Senderowitz H, Urbatsch IL. Hildebrandt E, et al. Among authors: urbatsch il. Biochim Biophys Acta Biomembr. 2017 Feb;1859(2):289-293. doi: 10.1016/j.bbamem.2016.11.013. Epub 2016 Nov 30. Biochim Biophys Acta Biomembr. 2017. PMID: 27913277 Free PMC article.
Domain-interface dynamics of CFTR revealed by stabilizing nanobodies.
Sigoillot M, Overtus M, Grodecka M, Scholl D, Garcia-Pino A, Laeremans T, He L, Pardon E, Hildebrandt E, Urbatsch I, Steyaert J, Riordan JR, Govaerts C. Sigoillot M, et al. Nat Commun. 2019 Jun 14;10(1):2636. doi: 10.1038/s41467-019-10714-y. Nat Commun. 2019. PMID: 31201318 Free PMC article.
Erratum to: A Stable Human-Cell System Overexpressing Cystic Fibrosis Transmembrane Conductance Regulator Recombinant Protein at the Cell Surface.
Hildebrandt E, Ding H, Mulky A, Dai Q, Aleksandrov AA, Bajrami B, Diego PA, Wu X, Ray M, Naren AP, Riordan JR, Yao X, DeLucas LJ, Urbatsch IL, Kappes JC. Hildebrandt E, et al. Among authors: urbatsch il. Mol Biotechnol. 2015 May;57(5):406. doi: 10.1007/s12033-015-9857-2. Mol Biotechnol. 2015. PMID: 25808031 No abstract available.
83 results