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Structural stability of purified human CFTR is systematically improved by mutations in nucleotide binding domain 1.
Yang Z, Hildebrandt E, Jiang F, Aleksandrov AA, Khazanov N, Zhou Q, An J, Mezzell AT, Xavier BM, Ding H, Riordan JR, Senderowitz H, Kappes JC, Brouillette CG, Urbatsch IL. Yang Z, et al. Among authors: jiang f. Biochim Biophys Acta Biomembr. 2018 May;1860(5):1193-1204. doi: 10.1016/j.bbamem.2018.02.006. Epub 2018 Feb 7. Biochim Biophys Acta Biomembr. 2018. PMID: 29425673 Free PMC article.
Folding correctors can restore CFTR posttranslational folding landscape by allosteric domain-domain coupling.
Soya N, Xu H, Roldan A, Yang Z, Ye H, Jiang F, Premchandar A, Veit G, Cole SPC, Kappes J, Hegedus T, Lukacs GL. Soya N, et al. Among authors: jiang f. bioRxiv [Preprint]. 2023 Oct 20:2023.10.19.563107. doi: 10.1101/2023.10.19.563107. bioRxiv. 2023. Update in: Nat Commun. 2023 Oct 27;14(1):6868. doi: 10.1038/s41467-023-42586-8 PMID: 37905074 Free PMC article. Updated. Preprint.
6,707 results