Hildebrandt E - Search Results

1

Structural stability of purified human CFTR is systematically improved by mutations in nucleotide binding domain 1.

Yang Z, Hildebrandt E, Jiang F, Aleksandrov AA, Khazanov N, Zhou Q, An J, Mezzell AT, Xavier BM, Ding H, Riordan JR, Senderowitz H, Kappes JC, Brouillette CG, Urbatsch IL. Yang Z, et al. Among authors: hildebrandt e. Biochim Biophys Acta Biomembr. 2018 May;1860(5):1193-1204. doi: 10.1016/j.bbamem.2018.02.006. Epub 2018 Feb 7. Biochim Biophys Acta Biomembr. 2018. PMID: 29425673 Free PMC article.

2

Substitution of Yor1p NBD1 residues improves the thermal stability of Human Cystic Fibrosis Transmembrane Conductance Regulator.

Xavier BM, Hildebrandt E, Jiang F, Ding H, Kappes JC, Urbatsch IL. Xavier BM, et al. Among authors: hildebrandt e. Protein Eng Des Sel. 2017 Oct 1;30(10):729-741. doi: 10.1093/protein/gzx054. Protein Eng Des Sel. 2017. PMID: 29053845 Free PMC article.

3

A survey of detergents for the purification of stable, active human cystic fibrosis transmembrane conductance regulator (CFTR).

Hildebrandt E, Zhang Q, Cant N, Ding H, Dai Q, Peng L, Fu Y, DeLucas LJ, Ford R, Kappes JC, Urbatsch IL. Hildebrandt E, et al. Biochim Biophys Acta. 2014 Nov;1838(11):2825-37. doi: 10.1016/j.bbamem.2014.07.016. Epub 2014 Jul 24. Biochim Biophys Acta. 2014. PMID: 25065669 Free PMC article.

4

A stable human-cell system overexpressing cystic fibrosis transmembrane conductance regulator recombinant protein at the cell surface.

Hildebrandt E, Mulky A, Ding H, Dai Q, Aleksandrov AA, Bajrami B, Diego PA, Wu X, Ray M, Naren AP, Riordan JR, Yao X, DeLucas LJ, Urbatsch IL, Kappes JC. Hildebrandt E, et al. Mol Biotechnol. 2015 May;57(5):391-405. doi: 10.1007/s12033-014-9830-5. Mol Biotechnol. 2015. PMID: 25577540 Free PMC article.

5

Specific stabilization of CFTR by phosphatidylserine.

Hildebrandt E, Khazanov N, Kappes JC, Dai Q, Senderowitz H, Urbatsch IL. Hildebrandt E, et al. Biochim Biophys Acta Biomembr. 2017 Feb;1859(2):289-293. doi: 10.1016/j.bbamem.2016.11.013. Epub 2016 Nov 30. Biochim Biophys Acta Biomembr. 2017. PMID: 27913277 Free PMC article.

6

Membrane protein stability can be compromised by detergent interactions with the extramembranous soluble domains.

Yang Z, Wang C, Zhou Q, An J, Hildebrandt E, Aleksandrov LA, Kappes JC, DeLucas LJ, Riordan JR, Urbatsch IL, Hunt JF, Brouillette CG. Yang Z, et al. Among authors: hildebrandt e. Protein Sci. 2014 Jun;23(6):769-89. doi: 10.1002/pro.2460. Epub 2014 May 3. Protein Sci. 2014. PMID: 24652590 Free PMC article.

7

Domain-interface dynamics of CFTR revealed by stabilizing nanobodies.

Sigoillot M, Overtus M, Grodecka M, Scholl D, Garcia-Pino A, Laeremans T, He L, Pardon E, Hildebrandt E, Urbatsch I, Steyaert J, Riordan JR, Govaerts C. Sigoillot M, et al. Among authors: hildebrandt e. Nat Commun. 2019 Jun 14;10(1):2636. doi: 10.1038/s41467-019-10714-y. Nat Commun. 2019. PMID: 31201318 Free PMC article.

8

A gene optimization strategy that enhances production of fully functional P-glycoprotein in Pichia pastoris.

Bai J, Swartz DJ, Protasevich II, Brouillette CG, Harrell PM, Hildebrandt E, Gasser B, Mattanovich D, Ward A, Chang G, Urbatsch IL. Bai J, et al. Among authors: hildebrandt e. PLoS One. 2011;6(8):e22577. doi: 10.1371/journal.pone.0022577. Epub 2011 Aug 3. PLoS One. 2011. PMID: 21826197 Free PMC article.

9

Erratum to: A Stable Human-Cell System Overexpressing Cystic Fibrosis Transmembrane Conductance Regulator Recombinant Protein at the Cell Surface.

Hildebrandt E, Ding H, Mulky A, Dai Q, Aleksandrov AA, Bajrami B, Diego PA, Wu X, Ray M, Naren AP, Riordan JR, Yao X, DeLucas LJ, Urbatsch IL, Kappes JC. Hildebrandt E, et al. Mol Biotechnol. 2015 May;57(5):406. doi: 10.1007/s12033-015-9857-2. Mol Biotechnol. 2015. PMID: 25808031 No abstract available.

10

Large-scale analysis of protein expression changes in human keratinocytes immortalized by human papilloma virus type 16 E6 and E7 oncogenes.

Merkley MA, Hildebrandt E, Podolsky RH, Arnouk H, Ferris DG, Dynan WS, Stöppler H. Merkley MA, et al. Among authors: hildebrandt e. Proteome Sci. 2009 Aug 23;7:29. doi: 10.1186/1477-5956-7-29. Proteome Sci. 2009. PMID: 19698150 Free PMC article.

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