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cGAS surveillance of micronuclei links genome instability to innate immunity.
Mackenzie KJ, Carroll P, Martin CA, Murina O, Fluteau A, Simpson DJ, Olova N, Sutcliffe H, Rainger JK, Leitch A, Osborn RT, Wheeler AP, Nowotny M, Gilbert N, Chandra T, Reijns MAM, Jackson AP. Mackenzie KJ, et al. Among authors: chandra t. Nature. 2017 Aug 24;548(7668):461-465. doi: 10.1038/nature23449. Epub 2017 Jul 24. Nature. 2017. PMID: 28738408 Free PMC article.
Notch Signaling Mediates Secondary Senescence.
Teo YV, Rattanavirotkul N, Olova N, Salzano A, Quintanilla A, Tarrats N, Kiourtis C, Müller M, Green AR, Adams PD, Acosta JC, Bird TG, Kirschner K, Neretti N, Chandra T. Teo YV, et al. Among authors: chandra t. Cell Rep. 2019 Apr 23;27(4):997-1007.e5. doi: 10.1016/j.celrep.2019.03.104. Cell Rep. 2019. PMID: 31018144 Free PMC article.
Kidney Single-Cell Atlas Reveals Myeloid Heterogeneity in Progression and Regression of Kidney Disease.
Conway BR, O'Sullivan ED, Cairns C, O'Sullivan J, Simpson DJ, Salzano A, Connor K, Ding P, Humphries D, Stewart K, Teenan O, Pius R, Henderson NC, Bénézech C, Ramachandran P, Ferenbach D, Hughes J, Chandra T, Denby L. Conway BR, et al. Among authors: chandra t. J Am Soc Nephrol. 2020 Dec;31(12):2833-2854. doi: 10.1681/ASN.2020060806. Epub 2020 Sep 25. J Am Soc Nephrol. 2020. PMID: 32978267 Free PMC article.
Epigenetic age prediction.
Simpson DJ, Chandra T. Simpson DJ, et al. Among authors: chandra t. Aging Cell. 2021 Sep;20(9):e13452. doi: 10.1111/acel.13452. Epub 2021 Aug 20. Aging Cell. 2021. PMID: 34415665 Free PMC article. Review.
Cellular reprogramming and epigenetic rejuvenation.
Simpson DJ, Olova NN, Chandra T. Simpson DJ, et al. Among authors: chandra t. Clin Epigenetics. 2021 Sep 6;13(1):170. doi: 10.1186/s13148-021-01158-7. Clin Epigenetics. 2021. PMID: 34488874 Free PMC article. Review.
Probabilistic inference of epigenetic age acceleration from cellular dynamics.
Dabrowski JK, Yang EJ, Crofts SJC, Hillary RF, Simpson DJ, McCartney DL, Marioni RE, Kirschner K, Latorre-Crespo E, Chandra T. Dabrowski JK, et al. Among authors: chandra t. Nat Aging. 2024 Oct;4(10):1493-1507. doi: 10.1038/s43587-024-00700-5. Epub 2024 Sep 23. Nat Aging. 2024. PMID: 39313745 Free PMC article.
350 results